Adjuvant Market by Application, Type and Geography - Forecast And Analysis 2023-2027

Adjuvant Market Size 2023-2027

 The adjuvant market size is forecast to increase by USD 1.89 billion at a CAGR of 6.71% between 2022 and 2027. The market's expansion hinges on several critical factors. First, the surge in vaccination initiatives globally is playing a pivotal role in driving market growth as governments and organizations prioritize immunization programs. Second, the escalating prevalence of infectious diseases worldwide has intensified the demand for pharmaceutical and biotechnology solutions, particularly in developing regions. Third, continuous advancements in biotechnology, including innovative drug delivery systems and precision medicine, are reshaping the industry landscape and attracting significant investments. Our comprehensive report delves into these factors, offering a detailed analysis of the current market scenario. Additionally, we provide a thorough examination of historical data spanning from 2017 to 2021. This historical perspective allows for a deeper understanding of market trends, challenges, and opportunities over the years, providing invaluable insights for stakeholders and decision-makers in the pharmaceutical and biotechnology sectors.

What will be the size of the Market During the Forecast Period?

Market Forecast 2023-2027

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Market Segmentation

This report extensively covers market segmentation by application (farming, veterinary medicine, medical and pharmacy, and others), type (agricultural adjuvant and vaccine adjuvant), and geography (North America, Europe, Asia, and Rest of World (ROW)). It also includes an in-depth analysis of drivers, trends, and challenges.

Market Dynamics

The global market is witnessing significant growth due to the increasing demand for effective vaccines against various diseases such as Influenza, Tuberculosis, Cholera, Polio, Measles, Malaria, HIV, and TB. Adjuvants play a crucial role in enhancing the immune response to vaccine antigens. Diphtheria, Tetanus, and Whooping cough are some diseases for which subunit vaccines and recombinant vaccines are being developed, requiring the use of adjuvants for optimal efficacy. Aluminum hydroxide and aluminum salts are commonly used adjuvants in vaccines due to their ability to stimulate humoral immunity and T cell responses. Other adjuvants include oil-based emulsions, bacterial compounds, and lipids. Private and public sector investors are actively participating in vaccine production and research, with companies like Adjuvance Technologies leading the way in developing new assistant technologies. The Respiratory syncytial virus is an emerging target for adjuvant development, with aluminum salts and bacterial compounds being explored as potential adjuvants. Our researchers studied the data for years, with 2022 as the base year and 2023 as the estimated year, and presented the key drivers, trends, and challenges for the market.   

Key Driver- Increasing vaccination initiatives

The global market for adjuvants is experiencing significant growth due to the heightened importance of vaccination programs and preventative healthcare, particularly in emerging nations. It plays a crucial role in enhancing vaccine effectiveness by stimulating the immune system, thereby increasing protection against various infectious diseases such as Influenza, Tuberculosis, Cholera, Polio, Measles, Malaria, HIV, and TB. The demand for assistant vaccines is increasing as governments prioritize immunization efforts, especially in areas where specific diseases are prevalent, like dengue fever in Southeast Asia and malaria in sub-Saharan Africa.

Moreover, the market encompasses various segments, including Aluminium adjuvanted vaccines, Anthrax vaccine, and assistant emulsions. Key adjuvant types include Squalene, Shark liver oil, saponin-based adjuvants, and particulate adjuvants. These are used in both human and veterinary vaccine production, with applications in diseases such as Diphtheria, Tetanus, Whooping cough, and others. Despite their benefits, it may pose side effects, including swelling and distal paresthesia at injection sites. Hence, such factors are expected to fuel market growth during the forecast period. 

Significant Trends- Rise of nanotechnology

The market has experienced significant growth due to advancements in nanotechnology, particularly in the creation of adjuvants based on nanoparticles. These innovative assistant enhance vaccine efficacy by precisely delivering antigens to immune cells, resulting in a stronger and more targeted immune response. Diseases such as Influenza, Tuberculosis, Cholera, Polio, Measles, Malaria, HIV, and TB have benefited from these advancements in vaccine production.

However, concerns regarding side effects and high toxicity, often associated with aluminum adjuvanted vaccines, have led government authorities to closely monitor their use. Pharmaceutical and biotechnology companies have responded by developing alternative assistants, such as squalene, shark liver oil, saponin-based adjuvants, and particulate adjuvants, for intramuscular and subcutaneous administration. Hence, the development of nanotechnology is expected to propel market growth during the targeted forecast period. 

Challenge- Safety concerns with adjuvants

The use of adjuvants in vaccine production for various infectious diseases, including Influenza, Tuberculosis, Cholera, Polio, Measles, Malaria, HIV, and TB, is crucial. However, safety concerns, such as side effects and high toxicity, can hinder market growth. For instance, the H1N1 influenza pandemic led to increased risks of side effects like narcolepsy and Guillain-Barre syndrome from certain adjuvants like AS03 and Pandemrix. To mitigate such risks, thorough preclinical and clinical assessments are necessary.

Moreover, adjuvants, such as Aluminium adjuvanted vaccines, Anthrax vaccine, and assistant emulsions segment, are used in the subcutaneous route and can cause swelling and ulnar nerve damage, leading to distal paresthesia. Government authorities and pharmaceutical, biotechnology companies are developing using Squalene, Shark liver oil, and pathogen components, as well as saponin-based and particulate for intramuscular and subcutaneous administration. Hence, such afctors are hindering the market during the forecast period.

Market Segmentation by Application, Type, Geography

Application Segment Analysis

The farming segment will account for a major share of the market's growth during the forecast period.?The global market experienced growth in 2022 due to increased usage in farming for enhancing agrochemical efficiency and boosting crop output. Factors driving this trend include the need for sustainable farming methods, advancements in adjuvant compositions, and the expanding global population.

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The farming segment was valued at USD 2.10 billion in 2017 and continued to grow until 2021.?In the pharmaceutical and biotechnology sectors, adjuvants are utilized in vaccine production to enhance immunity against various diseases such as Influenza, Tuberculosis, Cholera, Polio, Measles, Malaria, HIV, and TB. However, concerns regarding side effects and high toxicity, particularly with aluminum adjuvanted vaccines, persist. Adjuvant emulsions, pathogen components, saponin-based adjuvants, and particulate adjuvants are key segments.  Therefore, the demand for adjuvants is expected to increase from the farming application segment, which will drive the growth of the market during the forecast period. 

Type Segment Analysis

Based on type, the market has been segmented into agricultural adjuvant and vaccine adjuvant. The agricultural adjuvant?segment will account for the largest share of this segment.? The vaccine market encompasses various types of adjuvants used in Sub unit, Recombinant, Conjugate, DNA, and Live attenuated vaccines. Aluminum hydroxide is commonly used to enhance Humoral immunity and T cell responses. Private and public sector investors are increasingly funding Adjuvance Technologies to develop vaccines against diseases like Respiratory syncytial virus. Market growth is driven by the need for effective adjuvants to boost vaccine efficacy. Key players include Aluminum salts, Oil based emulsions, Bacterial compounds, Lipids, and Nucleic acids. Forecast scenarios suggest a Conservative, Base, or Optimistic growth trajectory. Patents and developer strength, as well as pipeline strength, are crucial factors influencing market dynamics. Other adjuvants include inactivated vaccines and adjuvants based on patented technologies. Thus, such factors will grow the demand and is expected to boost the growth of the market during the forecast period. 

Regional Analysis

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North America is estimated to contribute 37% to the growth by 2027. Technavio’s analysts have elaborately explained the regional trends, drivers, and challenges that are expected to shape the market during the forecast period. The market in North America is primarily driven by the healthcare and agriculture sectors. In healthcare, adjuvants such as aluminum hydroxide, oil-based emulsions, bacterial compounds, lipids, and nucleic acids are used to enhance the effectiveness of various types of vaccines, including subunit, recombinant, conjugate, DNA, live attenuated, and inactivated vaccines.

Moreover, these adjuvants boost humoral immunity and T cell responses, increasing vaccine potency. In agriculture, they are utilized to improve the efficiency of pesticides and herbicides. Aluminum salts and other they are employed to enhance the performance of these chemicals. Private and public sector investors are investing heavily in Adjuvance Technologies to develop cutting-edge solutions. Key focus areas include enhancing the efficacy of vaccines against diseases like Respiratory syncytial virus and addressing safety concerns. The market is forecasted to grow under conservative, base, and optimistic scenarios. Key players include those with strong developer and pipeline strengths. Patents play a crucial role in market competition. Hence, such factors will boost the growth of the market in this region during the forecast period.

Who are the Major Market Companies?

Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.

Solvay SA: The company offers adjuvant products such as rainfastness, wetting, compatibility, and other tank mix adjuvants.

We also have detailed analyses of the market’s competitive landscape and offer information on 20 market companies, including:

BASF SE, BRANDT Inc., Clariant International Ltd., Corteva Inc., Croda International Plc, Dow Chemical Co., GarrCo Products Inc., Huntsman International LLC, Innvictis Crop Care LLC, J.R. Simplot Co., Lamberti SpA, Land O Lakes Inc., Marubeni Corp., Nichino Europe Co. Ltd., Nouryon Chemicals Holding BV, Nufarm Ltd., RAG Stiftung, Stepan Co., and Wilbur Ellis Holdings Inc. 

Technavio report provides an in-depth market growth analysis of the market and its players through combined qualitative and quantitative data. The analysis classifies companies into categories based on their business approaches, including pure-play, category-focused, industry-focused, and diversified. Companies are specially categorized into dominant, leading, strong, tentative, and weak, based on their quantitative data analysis.  

Segment Overview

The market research report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Million" for the period 2023 to 2027, as well as historical data from 2017 to 2021 for the following segments.

• Application Outlook 
  • Farming
  • Veterinary medicine
  • Medical and pharmacy
  • Others

• Type Outlook 
  • Agricultural adjuvant
  • Vaccine adjuvant

• Region Outlook 
  • North America
    • The U.S.
    • Canada
  • Europe
    • The U.K.
    • Germany
    • France
    • Rest of Europe
  • Asia
    • China
    • India
  • Rest of the World 
    • Brazil 
    • Argentina
    • Australia

Market Analyst Overview

Adjuvants are essential components in vaccines and therapeutic proteins, enhancing the immune response to antigens. The global market is witnessing significant growth due to the increasing demand for effective vaccines and therapeutic proteins. The market is driven by factors such as the rising prevalence of infectious diseases, increasing government funding for vaccine research, and technological advancements in Private sector investors and adjuvant development. Cholecystokinin (CCK) and MALP-2 are some of the adjuvants used in vaccines and therapeutic proteins. CCK is a neuropeptide that plays a role in digestion and has been shown to enhance the immune response to antigens. MALP-2 is a bacterial protein that stimulates the immune system and is used as an adjuvant in various vaccines.

The market for adjuvants is segmented based on type, application, and region. The market for adjuvants in therapeutic proteins is expected to grow at a significant rate due to the increasing demand for effective therapeutic proteins. The market for adjuvants in vaccines is also expected to grow at a significant rate due to the increasing demand for effective vaccines. The market for adjuvants is competitive, with key players including companies such as DSM, Optimistic track, Seppic, and Invivogen. These companies are investing in research and development to develop new adjuvants and expand their product portfolios. In conclusion, the global Market is expected to grow significantly due to the increasing demand for effective vaccines and therapeutic proteins. The market is driven by factors such as the rising prevalence of infectious diseases, increasing government funding for vaccine research, and technological advancements in adjuvant development.

Market Scope
Report Coverage	Details
Page number	155
Base year	2022
Historic period	2017-2021
Forecast period	2023-2027
Growth momentum & CAGR	Accelerate at a CAGR of 6.71%
Market growth 2023-2027	USD 1.89 billion
Market structure	Fragmented
YoY growth 2022-2023(%)	6.57
Regional analysis	North America, Europe, Asia, and Rest of World (ROW)
Performing market contribution	North America at 37%
Key countries	US, France, Germany, China, and India
Competitive landscape	Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks
Key companies profiled	BASF SE, BRANDT Inc., Clariant International Ltd., Corteva Inc., Croda International Plc, Dow Chemical Co., GarrCo Products Inc., Huntsman International LLC, Innvictis Crop Care LLC, J.R. Simplot Co., Lamberti SpA, Land O Lakes Inc., Marubeni Corp., Nichino Europe Co. Ltd., Nouryon Chemicals Holding BV, Nufarm Ltd., RAG Stiftung, Solvay SA, Stepan Co., and Wilbur Ellis Holdings Inc.
Market dynamics	Parent market analysis, Market forecasting, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, market report, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for the forecast period.
Customization purview	If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

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What are the Key Data Covered in this Market Research Report?

• CAGR of the market during the forecast period
• Detailed information on factors that will drive the growth of the market between 2023 and 2027
• Precise estimation of the market size and its contribution to the market in focus on the parent market
• Accurate predictions about upcoming trends and changes in consumer behavior
• Growth of the market across North America, Europe, Asia, and Rest of World (ROW)
• A thorough market growth and forecasting analysis of the market’s competitive landscape and detailed information about companies
• Comprehensive market research and growth analysis of factors that will challenge the growth of market companies

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