Bone Grafts and Substitutes Market by Product, Application, and Geography - Forecast and Analysis 2023-2027

Published: Feb 2023 Pages: 173 SKU: IRTNTR73350

Bone Grafts and Substitutes Market Forecast 2023-2027

The bone grafts and substitutes market is estimated to increase by USD 1.45 billion and grow at a CAGR of 8.71% between 2022 and 2027. Primary factors that are driving the market growth include the growing prevalence of orthopedic conditions, the increasing demand for dental bone grafts, and the rising investment in clinical trials. Market expansion is notably propelled by the increasing prevalence of orthopedic conditions. As per the Arthritis Foundation, it's projected that by 2050, approximately 130 million individuals worldwide will suffer from degenerative joint diseases like osteoarthritis. These conditions necessitate treatments such as addressing fractures and dislocations in the lower extremities, performing total and partial hip replacements, and conducting spinal fusions. Utilized post-cervical or lumbar spine surgeries,  growth stimulation devices administer low-intensity electrical signals to stimulate the innate healing process, particularly for spinal fusion procedures.

What will be the Size of the Bone Grafts and Substitutes Market During the Forecast Period?

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Market Segmentation

This report extensively covers market segmentation by product (xenografts, allografts, synthetic bone grafts, and DBM), application (spinal fusion, trauma, craniomaxillofacial, joint reconstruction, and dental bone grafting), and geography (North America, Europe, Asia, and Rest of World (ROW)). It also includes an in-depth analysis of drivers, trends, and challenges.

By Product

The market share growth by the xenografts segment will be significant during the forecast period. Xenografts are defined as transplants between closely related species. They serve as biological dressings that protect wounds from bacterial and physical trauma. The growth of this segment is attributed to factors such as the increasing prevalence of knee and hip injuries, technological advances such as 3D-printed implants, and new product launches by key players.

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The xenografts segment was valued at USD 1.24 billion in 2017 and continued to grow until 2021. Xenografts are widely used for R&D, as they create microenvironments closer to a tumor's physiological and pathological conditions. Therefore, the growth of the xenograft segment is expected to drive the global bone graft and substitute market during the forecast period.

Key Regions

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North America is estimated to contribute 33% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.

The growth of the market in the region is attributed to factors such as the rising prevalence of orthopedic conditions, product launches, favorable reimbursement for orthopedic implants, and awareness initiatives by governments and non-profit organizations. The increase in the prevalence of orthopedic conditions will augment the demand in the region. For instance, according to the CDC, the prevalence of arthritis in the US is expected to increase in the coming years. Vendors are promoting the use by providing performance guarantees. For instance, in February 2022, Orthofix Medical announced the launch of Opus BA, a synthetic bioactive bone graft solution. Therefore, the launch of new products and approvals for the inclusion of new indications are expected to drive market growth during the forecast period. 

Market Dynamics and Customer Landscape

The Market is experiencing notable growth, driven by the increasing prevalence of conditions such as degenerative disc disease (DDD), fractured bones, and facial fractures due to sports injuries, falls, and road accidents. With a growing geriatric population and rising demand for minimally invasive surgeries, the market for bone grafts and substitutes is witnessing significant traction. These products play a crucial role in orthopedic procedures such as joint reconstruction, spinal fusion, and dental bone grafts, addressing a wide range of conditions, including hip fractures, spinal injuries, and bone cancer. Synthetic substitutes, including powders, granules, pastes, and putties, offer viable alternatives to traditional bone tissue grafts, meeting the regulatory standards set by authorities and providing surgeons with versatile options for patient care. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.

Key Market Driver

The growing prevalence of orthopedic conditions is notably driving market growth. According to the Arthritis Foundation, by 2050, 130 million people across the world will have degenerative joint diseases or disorders such as osteoarthritis. They are used for treating conditions such as fractures and dislocation of the lower extremities, total and partial hip replacements, and spinal fusions. A growth stimulation device is used for spinal fusion after cervical or lumbar spine surgery to deliver low-intensity electrical signals, which stimulate the natural healing process. Various companies offer growth stimulation devices. For instance, Orthofix Medical Inc. has developed Physio-Stim for hip fractures. Therefore, the increasing prevalence of injuries and the availability of a wide variety of products are expected to drive the market during the forecast period.

Significant Market Trend

The growing adoption of minimally invasive surgeries is a key trend influencing the market growth. Minimally invasive surgeries provide various benefits to patients, such as less pain and discomfort, low chances of infection and bleeding, shorter hospital stays, reduced chances of scars, and quick recovery. Minimally invasive surgeries are used for various procedures, such as arthroscopy, joint replacement, and spine fusion. The grafting technique is a new, minimally invasive technique that leads to improved outcomes with less pain and fewer complications. The presence of specialist orthopedic care centers is expected to increase the adoption of minimally invasive surgeries. Thus, the growing adoption of minimally invasive surgeries is expected to increase their use, which will fuel the market growth during the forecast period.

Major Market Challenge

The high costs associated with implants and procedures may impede bone grafts and substitute market growth. Orthopedic implants are used for the treatment of conditions related to the joints, spine, and maxillofacial injuries. The cost depends on their applications and features. For instance, the cost of a simple graft is higher than the cost of synthetic substitutes. The high costs can increase the cost burden on end-users and patients. For instance, the average cost of inpatient bone grafting procedures ranges from USD 25,000 to USD 30,000. Post-surgical diagnostic tests can further increase the cost burden. For instance, the average cost of a CT scan ranges between USD 750 and USD 1,300 per orthopedic procedure. Such factors are expected to hinder the growth of the market during the forecast period.

Key Market Customer Landscape

The report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.

Global Market Customer Landscape

Who are the Major Bone Grafts and Substitutes Market Companies?

Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.

  • AlloSource - The company offers solutions for bone grafts and substitutes, which comprise demineralized bone matrix in a reverse phase medium.

The report also includes detailed analyses of the competitive landscape of the market and information about 15 market vendors, including:

  • Arthrex Inc.
  • Baxter International Inc.
  • Bioventus LLC
  • Geistlich Pharma AG
  • Integra Lifesciences Holdings Corp.
  • Johnson and Johnson
  • Medtronic Plc
  • MTF Biologics
  • NovaBone Products LLC
  • Nuvasive Inc.
  • Orthofix Medical Inc.
  • OST Laboratories
  • RTI Surgical Inc.
  • SeaSpine Holdings Corp.
  • Smith and Nephew plc

Qualitative and quantitative analysis of vendors has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize vendors as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize vendors as dominant, leading, strong, tentative, and weak.

Segment Overview

The report forecasts market growth by revenue at global, regional, and country levels and provides an analysis of the latest trends and growth opportunities from 2017 to 2027. 

  • Product Outlook
    • Xenografts 
    • Allografts 
    • Synthetic bone grafts 
    • DBM 
  • Application Outlook 
    • Spinal fusion
    • Trauma 
    • Craniomaxillofacial 
    • Joint reconstruction 
    • Dental bone grafting
  • Region Outlook 
    • North America
      • The U.S.
      • Canada
    • Europe
      • The U.K.
      • Germany
      • France
      • Rest of Europe
    • Asia
      • China
      • India
    • ROW
      • Australia
      • Argentina
      • Rest of the world

Market Analyst Overview

The Market is experiencing rapid growth fueled by rising cases of bone disorders, fractures, and degeneration, necessitating effective treatment options. With advancements in medical technology, orthopedic procedures like joint replacements, spine surgeries, and fracture repairs are becoming increasingly common, driving the demand for bone grafts and substitutes. Players in the market are innovating with biocomposites, synthetic substitutes, and cell-based matrices to facilitate bone regeneration and repair. Surgeons utilize a variety of materials, including ceramics, polymers, and sterile calcium phosphate resorbable fillers, to address diverse orthopedic needs. The market is also witnessing increased adoption of minimally invasive procedures and long bone graft substitutes, catering to the growing geriatric population and addressing orthopedic disorders prevalent in medical tourism destinations. Regulatory authorities play a crucial role in ensuring the safety and efficacy of these products amidst growing healthcare infrastructure and demand.

Moreover, the market is experiencing significant growth within the healthcare sector, driven by factors such as bone fractures, degeneration, and diseases like osteoporosis and bone cancer. Surgeons frequently utilize bone grafts and substitutes in procedures ranging from joint replacements to craniomaxillofacial surgeries, addressing conditions such as spinal deformities and facial fractures. Technologies like HCCP and products like Osteo-P Synthetic Bone Graft Substitute offer innovative solutions for bone repair and regeneration. The market also benefits from the rising demand for medical tourism and the increasing incidence of road accidents and sports injuries necessitating fracture repair and spinal fusion surgeries. Regulatory frameworks ensure the safety and efficacy of bone graft materials, supporting the market's expansion in catering to diverse orthopedic needs.

Additionally, the market is witnessing substantial growth amidst increasing concerns related to bone degeneration, fractures, and spinal disorders. Allografts, bone morphogenic proteins (BMP), and sterile calcium phosphate resorbable bone void fillers are among the key substitutes utilized in orthopedic and craniomaxillofacial surgeries. Surgeons often rely on ceramic composites and HCCP technology to address degenerative disc disease (DDD) and joint replacement procedures, including knee and lumbar spinal fusion surgeries. The market is also buoyed by advancements in dental implant surgical procedures and foot & ankle surgeries, catering to the growing demand from the healthcare sector and medical tourism industry. Regulatory frameworks play a crucial role in ensuring the safety and efficacy of bone grafts and substitutes as organizations like Graftys and Renovos continue to innovate to meet the evolving needs of patients and surgeons alike.

Bone Grafts and Substitutes Market Scope

Report Coverage

Details

Page number

173

Base year

2022

Historic period

2017-2021

Forecast period

2023-2027

Growth momentum & CAGR

Accelerate at a CAGR of 8.71%

Market growth 2023-2027

USD 1.45 billion

Market structure

Fragmented

YoY growth 2022-2023(%)

7.69

Regional analysis

North America, Europe, Asia, and Rest of World (ROW)

Performing market contribution

North America at 33%

Key countries

US, Germany, UK, China, and Japan

Competitive landscape

 Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks

Key companies profiled

AlloSource, Arthrex Inc., Baxter International Inc., Bioventus LLC, Geistlich Pharma AG, Integra Lifesciences Holdings Corp., Johnson and Johnson, Medtronic Plc, MTF Biologics, NovaBone Products LLC, Nuvasive Inc., Orthofix Medical Inc., OST Laboratories, RTI Surgical Inc., SeaSpine Holdings Corp., Smith and Nephew plc, Stryker Corp., TBF TISSUE ENGINEERING, Xtant Medical Inc., and Zimmer Biomet Holdings Inc.

Market dynamics

Parent market analysis, Market forecasting, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period.

Customization purview

If our market research report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

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What are the Key Data Covered in this Market Report?

  • CAGR of the market during the forecast period
  • Detailed information on factors that will drive the market growth and forecasting of the market between 2023 and 2027
  • Precise estimation of the size of the market size and its contribution to the parent market
  • Accurate predictions about upcoming market trends and analysis and changes in consumer behavior
  • Growth of the market industry across Europe, North America, APAC, South America, and Middle East and Africa
  • Thorough market growth analysis of the market’s competitive landscape and detailed information about vendors
  • Comprehensive market analysis and report on the factors that will challenge the market research and growth of market companies

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1 Executive Summary

  • 1.1 Market overview
    • Exhibit 01: Executive Summary – Chart on Market Overview
    • Exhibit 02: Executive Summary – Data Table on Market Overview
    • Exhibit 03: Executive Summary – Chart on Global Market Characteristics
    • Exhibit 04: Executive Summary – Chart on Market by Geography
    • Exhibit 05: Executive Summary – Chart on Market Segmentation by Product
    • Exhibit 06: Executive Summary – Chart on Market Segmentation by Application
    • Exhibit 07: Executive Summary – Chart on Incremental Growth
    • Exhibit 08: Executive Summary – Data Table on Incremental Growth
    • Exhibit 09: Executive Summary – Chart on Vendor Market Positioning

2 Market Landscape

  • 2.1 Market ecosystem
    • Exhibit 10: Parent market
    • Exhibit 11: Market Characteristics

3 Market Sizing

  • 3.1 Market definition
    • Exhibit 12: Offerings of vendors included in the market definition
  • 3.2 Market segment analysis
    • Exhibit 13: Market segments
  • 3.3 Market size 2022
    • 3.4 Market outlook: Forecast for 2022-2027
      • Exhibit 14: Chart on Global - Market size and forecast 2022-2027 ($ million)
      • Exhibit 15: Data Table on Global - Market size and forecast 2022-2027 ($ million)
      • Exhibit 16: Chart on Global Market: Year-over-year growth 2022-2027 (%)
      • Exhibit 17: Data Table on Global Market: Year-over-year growth 2022-2027 (%)

    4 Historic Market Size

    • 4.1 Global bone grafts and substitutes market 2017 - 2021
      • Exhibit 18: Historic Market Size – Data Table on Global bone grafts and substitutes market 2017 - 2021 ($ million)
    • 4.2 Product Segment Analysis 2017 - 2021
      • Exhibit 19: Historic Market Size – Product Segment 2017 - 2021 ($ million)
    • 4.3 Application Segment Analysis 2017 - 2021
      • Exhibit 20: Historic Market Size – Application Segment 2017 - 2021 ($ million)
    • 4.4 Geography Segment Analysis 2017 - 2021
      • Exhibit 21: Historic Market Size – Geography Segment 2017 - 2021 ($ million)
    • 4.5 Country Segment Analysis 2017 - 2021
      • Exhibit 22: Historic Market Size – Country Segment 2017 - 2021 ($ million)

    5 Five Forces Analysis

    • 5.1 Five forces summary
      • Exhibit 23: Five forces analysis - Comparison between 2022 and 2027
    • 5.2 Bargaining power of buyers
      • Exhibit 24: Chart on Bargaining power of buyers – Impact of key factors 2022 and 2027
    • 5.3 Bargaining power of suppliers
      • Exhibit 25: Bargaining power of suppliers – Impact of key factors in 2022 and 2027
    • 5.4 Threat of new entrants
      • Exhibit 26: Threat of new entrants – Impact of key factors in 2022 and 2027
    • 5.5 Threat of substitutes
      • Exhibit 27: Threat of substitutes – Impact of key factors in 2022 and 2027
    • 5.6 Threat of rivalry
      • Exhibit 28: Threat of rivalry – Impact of key factors in 2022 and 2027
    • 5.7 Market condition
      • Exhibit 29: Chart on Market condition - Five forces 2022 and 2027

    6 Market Segmentation by Product

    • 6.1 Market segments
      • Exhibit 30: Chart on Product - Market share 2022-2027 (%)
      • Exhibit 31: Data Table on Product - Market share 2022-2027 (%)
    • 6.2 Comparison by Product
      • Exhibit 32: Chart on Comparison by Product
      • Exhibit 33: Data Table on Comparison by Product
    • 6.3 Xenografts - Market size and forecast 2022-2027
      • Exhibit 34: Chart on Xenografts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 35: Data Table on Xenografts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 36: Chart on Xenografts - Year-over-year growth 2022-2027 (%)
      • Exhibit 37: Data Table on Xenografts - Year-over-year growth 2022-2027 (%)
    • 6.4 Allografts - Market size and forecast 2022-2027
      • Exhibit 38: Chart on Allografts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 39: Data Table on Allografts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 40: Chart on Allografts - Year-over-year growth 2022-2027 (%)
      • Exhibit 41: Data Table on Allografts - Year-over-year growth 2022-2027 (%)
    • 6.5 Synthetic bone grafts - Market size and forecast 2022-2027
      • Exhibit 42: Chart on Synthetic bone grafts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 43: Data Table on Synthetic bone grafts - Market size and forecast 2022-2027 ($ million)
      • Exhibit 44: Chart on Synthetic bone grafts - Year-over-year growth 2022-2027 (%)
      • Exhibit 45: Data Table on Synthetic bone grafts - Year-over-year growth 2022-2027 (%)
    • 6.6 DBM - Market size and forecast 2022-2027
      • Exhibit 46: Chart on DBM - Market size and forecast 2022-2027 ($ million)
      • Exhibit 47: Data Table on DBM - Market size and forecast 2022-2027 ($ million)
      • Exhibit 48: Chart on DBM - Year-over-year growth 2022-2027 (%)
      • Exhibit 49: Data Table on DBM - Year-over-year growth 2022-2027 (%)
    • 6.7 Market opportunity by Product
      • Exhibit 50: Market opportunity by Product ($ million)
      • Exhibit 51: Data Table on Market opportunity by Product ($ million)

    7 Market Segmentation by Application

    • 7.1 Market segments
      • Exhibit 52: Chart on Application - Market share 2022-2027 (%)
      • Exhibit 53: Data Table on Application - Market share 2022-2027 (%)
    • 7.2 Comparison by Application
      • Exhibit 54: Chart on Comparison by Application
      • Exhibit 55: Data Table on Comparison by Application
    • 7.3 Spinal fusion - Market size and forecast 2022-2027
      • Exhibit 56: Chart on Spinal fusion - Market size and forecast 2022-2027 ($ million)
      • Exhibit 57: Data Table on Spinal fusion - Market size and forecast 2022-2027 ($ million)
      • Exhibit 58: Chart on Spinal fusion - Year-over-year growth 2022-2027 (%)
      • Exhibit 59: Data Table on Spinal fusion - Year-over-year growth 2022-2027 (%)
    • 7.4 Trauma - Market size and forecast 2022-2027
      • Exhibit 60: Chart on Trauma - Market size and forecast 2022-2027 ($ million)
      • Exhibit 61: Data Table on Trauma - Market size and forecast 2022-2027 ($ million)
      • Exhibit 62: Chart on Trauma - Year-over-year growth 2022-2027 (%)
      • Exhibit 63: Data Table on Trauma - Year-over-year growth 2022-2027 (%)
    • 7.5 Craniomaxillofacial - Market size and forecast 2022-2027
      • Exhibit 64: Chart on Craniomaxillofacial - Market size and forecast 2022-2027 ($ million)
      • Exhibit 65: Data Table on Craniomaxillofacial - Market size and forecast 2022-2027 ($ million)
      • Exhibit 66: Chart on Craniomaxillofacial - Year-over-year growth 2022-2027 (%)
      • Exhibit 67: Data Table on Craniomaxillofacial - Year-over-year growth 2022-2027 (%)
    • 7.6 Joint reconstruction - Market size and forecast 2022-2027
      • Exhibit 68: Chart on Joint reconstruction - Market size and forecast 2022-2027 ($ million)
      • Exhibit 69: Data Table on Joint reconstruction - Market size and forecast 2022-2027 ($ million)
      • Exhibit 70: Chart on Joint reconstruction - Year-over-year growth 2022-2027 (%)
      • Exhibit 71: Data Table on Joint reconstruction - Year-over-year growth 2022-2027 (%)
    • 7.7 Dental bone grafting - Market size and forecast 2022-2027
      • Exhibit 72: Chart on Dental bone grafting - Market size and forecast 2022-2027 ($ million)
      • Exhibit 73: Data Table on Dental bone grafting - Market size and forecast 2022-2027 ($ million)
      • Exhibit 74: Chart on Dental bone grafting - Year-over-year growth 2022-2027 (%)
      • Exhibit 75: Data Table on Dental bone grafting - Year-over-year growth 2022-2027 (%)
    • 7.8 Market opportunity by Application
      • Exhibit 76: Market opportunity by Application ($ million)
      • Exhibit 77: Data Table on Market opportunity by Application ($ million)

    8 Customer Landscape

    • 8.1 Customer landscape overview
      • Exhibit 78: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria

    9 Geographic Landscape

    • 9.1 Geographic segmentation
      • Exhibit 79: Chart on Market share by geography 2022-2027 (%)
      • Exhibit 80: Data Table on Market share by geography 2022-2027 (%)
    • 9.2 Geographic comparison
      • Exhibit 81: Chart on Geographic comparison
      • Exhibit 82: Data Table on Geographic comparison
    • 9.3 North America - Market size and forecast 2022-2027
      • Exhibit 83: Chart on North America - Market size and forecast 2022-2027 ($ million)
      • Exhibit 84: Data Table on North America - Market size and forecast 2022-2027 ($ million)
      • Exhibit 85: Chart on North America - Year-over-year growth 2022-2027 (%)
      • Exhibit 86: Data Table on North America - Year-over-year growth 2022-2027 (%)
    • 9.4 Europe - Market size and forecast 2022-2027
      • Exhibit 87: Chart on Europe - Market size and forecast 2022-2027 ($ million)
      • Exhibit 88: Data Table on Europe - Market size and forecast 2022-2027 ($ million)
      • Exhibit 89: Chart on Europe - Year-over-year growth 2022-2027 (%)
      • Exhibit 90: Data Table on Europe - Year-over-year growth 2022-2027 (%)
    • 9.5 Asia - Market size and forecast 2022-2027
      • Exhibit 91: Chart on Asia - Market size and forecast 2022-2027 ($ million)
      • Exhibit 92: Data Table on Asia - Market size and forecast 2022-2027 ($ million)
      • Exhibit 93: Chart on Asia - Year-over-year growth 2022-2027 (%)
      • Exhibit 94: Data Table on Asia - Year-over-year growth 2022-2027 (%)
    • 9.6 Rest of World (ROW) - Market size and forecast 2022-2027
      • Exhibit 95: Chart on Rest of World (ROW) - Market size and forecast 2022-2027 ($ million)
      • Exhibit 96: Data Table on Rest of World (ROW) - Market size and forecast 2022-2027 ($ million)
      • Exhibit 97: Chart on Rest of World (ROW) - Year-over-year growth 2022-2027 (%)
      • Exhibit 98: Data Table on Rest of World (ROW) - Year-over-year growth 2022-2027 (%)
    • 9.7 US - Market size and forecast 2022-2027
      • Exhibit 99: Chart on US - Market size and forecast 2022-2027 ($ million)
      • Exhibit 100: Data Table on US - Market size and forecast 2022-2027 ($ million)
      • Exhibit 101: Chart on US - Year-over-year growth 2022-2027 (%)
      • Exhibit 102: Data Table on US - Year-over-year growth 2022-2027 (%)
    • 9.8 Germany - Market size and forecast 2022-2027
      • Exhibit 103: Chart on Germany - Market size and forecast 2022-2027 ($ million)
      • Exhibit 104: Data Table on Germany - Market size and forecast 2022-2027 ($ million)
      • Exhibit 105: Chart on Germany - Year-over-year growth 2022-2027 (%)
      • Exhibit 106: Data Table on Germany - Year-over-year growth 2022-2027 (%)
    • 9.9 UK - Market size and forecast 2022-2027
      • Exhibit 107: Chart on UK - Market size and forecast 2022-2027 ($ million)
      • Exhibit 108: Data Table on UK - Market size and forecast 2022-2027 ($ million)
      • Exhibit 109: Chart on UK - Year-over-year growth 2022-2027 (%)
      • Exhibit 110: Data Table on UK - Year-over-year growth 2022-2027 (%)
    • 9.10 China - Market size and forecast 2022-2027
      • Exhibit 111: Chart on China - Market size and forecast 2022-2027 ($ million)
      • Exhibit 112: Data Table on China - Market size and forecast 2022-2027 ($ million)
      • Exhibit 113: Chart on China - Year-over-year growth 2022-2027 (%)
      • Exhibit 114: Data Table on China - Year-over-year growth 2022-2027 (%)
    • 9.11 Japan - Market size and forecast 2022-2027
      • Exhibit 115: Chart on Japan - Market size and forecast 2022-2027 ($ million)
      • Exhibit 116: Data Table on Japan - Market size and forecast 2022-2027 ($ million)
      • Exhibit 117: Chart on Japan - Year-over-year growth 2022-2027 (%)
      • Exhibit 118: Data Table on Japan - Year-over-year growth 2022-2027 (%)
    • 9.12 Market opportunity by geography
      • Exhibit 119: Market opportunity by geography ($ million)
      • Exhibit 120: Data Tables on Market opportunity by geography ($ million)

    10 Drivers, Challenges, and Trends

    • 10.1 Market drivers
      • 10.2 Market challenges
        • 10.3 Impact of drivers and challenges
          • Exhibit 121: Impact of drivers and challenges in 2022 and 2027
        • 10.4 Market trends

          11 Vendor Landscape

          • 11.1 Overview
            • 11.2 Vendor landscape
              • Exhibit 122: Overview on Criticality of inputs and Factors of differentiation
            • 11.3 Landscape disruption
              • Exhibit 123: Overview on factors of disruption
            • 11.4 Industry risks
              • Exhibit 124: Impact of key risks on business

            12 Vendor Analysis

            • 12.1 Vendors covered
              • Exhibit 125: Vendors covered
            • 12.2 Market positioning of vendors
              • Exhibit 126: Matrix on vendor position and classification
            • 12.3 AlloSource
              • Exhibit 127: AlloSource - Overview
              • Exhibit 128: AlloSource - Product / Service
              • Exhibit 129: AlloSource - Key offerings
            • 12.4 Arthrex Inc.
              • Exhibit 130: Arthrex Inc. - Overview
              • Exhibit 131: Arthrex Inc. - Product / Service
              • Exhibit 132: Arthrex Inc. - Key offerings
            • 12.5 Baxter International Inc.
              • Exhibit 133: Baxter International Inc. - Overview
              • Exhibit 134: Baxter International Inc. - Business segments
              • Exhibit 135: Baxter International Inc. - Key news
              • Exhibit 136: Baxter International Inc. - Key offerings
              • Exhibit 137: Baxter International Inc. - Segment focus
            • 12.6 Bioventus LLC
              • Exhibit 138: Bioventus LLC - Overview
              • Exhibit 139: Bioventus LLC - Business segments
              • Exhibit 140: Bioventus LLC - Key news
              • Exhibit 141: Bioventus LLC - Key offerings
              • Exhibit 142: Bioventus LLC - Segment focus
            • 12.7 Geistlich Pharma AG
              • Exhibit 143: Geistlich Pharma AG - Overview
              • Exhibit 144: Geistlich Pharma AG - Product / Service
              • Exhibit 145: Geistlich Pharma AG - Key offerings
            • 12.8 Integra Lifesciences Holdings Corp.
              • Exhibit 146: Integra Lifesciences Holdings Corp. - Overview
              • Exhibit 147: Integra Lifesciences Holdings Corp. - Business segments
              • Exhibit 148: Integra Lifesciences Holdings Corp. - Key news
              • Exhibit 149: Integra Lifesciences Holdings Corp. - Key offerings
              • Exhibit 150: Integra Lifesciences Holdings Corp. - Segment focus
            • 12.9 Johnson and Johnson
              • Exhibit 151: Johnson and Johnson - Overview
              • Exhibit 152: Johnson and Johnson - Business segments
              • Exhibit 153: Johnson and Johnson - Key news
              • Exhibit 154: Johnson and Johnson - Key offerings
              • Exhibit 155: Johnson and Johnson - Segment focus
            • 12.10 Medtronic Plc
              • Exhibit 156: Medtronic Plc - Overview
              • Exhibit 157: Medtronic Plc - Business segments
              • Exhibit 158: Medtronic Plc - Key news
              • Exhibit 159: Medtronic Plc - Key offerings
              • Exhibit 160: Medtronic Plc - Segment focus
            • 12.11 MTF Biologics
              • Exhibit 161: MTF Biologics - Overview
              • Exhibit 162: MTF Biologics - Product / Service
              • Exhibit 163: MTF Biologics - Key offerings
            • 12.12 NovaBone Products LLC
              • Exhibit 164: NovaBone Products LLC - Overview
              • Exhibit 165: NovaBone Products LLC - Product / Service
              • Exhibit 166: NovaBone Products LLC - Key offerings
            • 12.13 Nuvasive Inc.
              • Exhibit 167: Nuvasive Inc. - Overview
              • Exhibit 168: Nuvasive Inc. - Business segments
              • Exhibit 169: Nuvasive Inc. - Key news
              • Exhibit 170: Nuvasive Inc. - Key offerings
              • Exhibit 171: Nuvasive Inc. - Segment focus
            • 12.14 Orthofix Medical Inc.
              • Exhibit 172: Orthofix Medical Inc. - Overview
              • Exhibit 173: Orthofix Medical Inc. - Business segments
              • Exhibit 174: Orthofix Medical Inc. - Key news
              • Exhibit 175: Orthofix Medical Inc. - Key offerings
              • Exhibit 176: Orthofix Medical Inc. - Segment focus
            • 12.15 OST Laboratories
              • Exhibit 177: OST Laboratories - Overview
              • Exhibit 178: OST Laboratories - Product / Service
              • Exhibit 179: OST Laboratories - Key offerings
            • 12.16 Smith and Nephew plc
              • Exhibit 180: Smith and Nephew plc - Overview
              • Exhibit 181: Smith and Nephew plc - Business segments
              • Exhibit 182: Smith and Nephew plc - Key news
              • Exhibit 183: Smith and Nephew plc - Key offerings
              • Exhibit 184: Smith and Nephew plc - Segment focus
            • 12.17 Stryker Corp.
              • Exhibit 185: Stryker Corp. - Overview
              • Exhibit 186: Stryker Corp. - Business segments
              • Exhibit 187: Stryker Corp. - Key news
              • Exhibit 188: Stryker Corp. - Key offerings
              • Exhibit 189: Stryker Corp. - Segment focus

            13 Appendix

            • 13.1 Scope of the report
              • 13.2 Inclusions and exclusions checklist
                • Exhibit 190: Inclusions checklist
                • Exhibit 191: Exclusions checklist
              • 13.3 Currency conversion rates for US$
                • Exhibit 192: Currency conversion rates for US$
              • 13.4 Research methodology
                • Exhibit 193: Research methodology
                • Exhibit 194: Validation techniques employed for market sizing
                • Exhibit 195: Information sources
              • 13.5 List of abbreviations
                • Exhibit 196: List of abbreviations

              Research Framework

              Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.

              INFORMATION SOURCES

              Primary sources

              • Manufacturers and suppliers
              • Channel partners
              • Industry experts
              • Strategic decision makers

              Secondary sources

              • Industry journals and periodicals
              • Government data
              • Financial reports of key industry players
              • Historical data
              • Press releases

              DATA ANALYSIS

              Data Synthesis

              • Collation of data
              • Estimation of key figures
              • Analysis of derived insights

              Data Validation

              • Triangulation with data models
              • Reference against proprietary databases
              • Corroboration with industry experts

              REPORT WRITING

              Qualitative

              • Market drivers
              • Market challenges
              • Market trends
              • Five forces analysis

              Quantitative

              • Market size and forecast
              • Market segmentation
              • Geographical insights
              • Competitive landscape

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              bone grafts and substitutes market

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              Key Questions Answered

              • What are the key global market and the regional market share?
              • What are the revenue-generating key market segments?
              • What are the key factors driving and challenging this market’s growth?
              • Who are the key market vendors and their growth strategies?
              • What are the latest trends influencing the growth of this market?
              • What are the variables influencing the market growth in the primary regions?
              • What are the factors influencing the growth of the parent market?

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              • Data on revenue-generating market segments
              • Details on the market shares of various regions
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