Cell Culture Consumables Market by Application, and Geography - Forecast and Analysis 2023-2027

Cell Culture Consumables Market Forecast 2023-2027

The cell culture consumables market size is estimated to grow by USD 23.73 billion at a CAGR of 22.3% between 2022 and 2027. The increase in the production of cell culture-based viral vaccines is driven by the need for more effective and scalable vaccine production methods, particularly in response to outbreaks of infectious diseases. The growing demand for monoclonal antibodies is driven by their effectiveness in treating a variety of diseases, including cancer, autoimmune disorders, and infectious diseases. The increased focus on stem cell research is driving demand for stem cell-based therapies and products, as researchers explore new ways to treat diseases and regenerate damaged tissues.

What will be the size of the Cell Culture Consumables Market During the Forecast Period?

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Market Segmentation

This market report extensively covers market segmentation by application (biopharmaceutical production, cancer research, and others) and geography (North America, Europe, Asia, and Rest of World). It also includes an in-depth analysis of drivers, trends, and challenges. Furthermore, the report consists of historic market data from 2017 to 2021.

By Application

The market share growth by the biopharmaceutical production segment will be significant during the forecast period. The biopharmaceutical production segment held the largest market share in 2022 among all applications due to the recurrent purchase of media, sera, and reagents for various cell culture applications, such as the production of vaccines and recombinant therapeutic proteins.

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The biopharmaceutical production segment had a value of USD 2.97 billion in 2017 and has grown steadily since then. The technology has been widely employed for vaccine production since the 1950s, with various vaccines being created using animal cultures for diseases such as polio, rubella, chickenpox, mumps, and measles. Due to the significant increase in the incidence of infectious diseases in recent years, manufacturers have been prompted to develop new drugs, vaccines, and biopharmaceutical agents using these methods. These consumables are also used to produce protein therapeutics, including peptides, recombinant proteins, and monoclonal antibodies. While bacterial or yeast cultures are used to produce pharmaceutical proteins like insulin, albumin, and growth hormones, mammalian cultures are utilized to produce human proteins with high therapeutic potentials such as tissue plasminogen activators, clotting factors, and erythropoietin. Furthermore, pharmaceutical recombinant proteins are increasingly used to treat various illnesses, including diabetes, anemia, cancer, and hepatitis, which is driving demand for these consumables since they are employed in these techniques. Significant progress in this technology, such as media development, feeding strategies, cell line engineering, and metabolism, has been made due to intensive research, and this is also fueling the growth of this sector. Therefore, these factors are expected to drive the growth of the biopharmaceutical production segment in the global market during the forecast period.

By Region

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North America is estimated to contribute 46% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.

North America accounted for the largest market share in 2022 and is expected to retain its market-leading position through the forecast period. This can be attributed to the growing research on stem cells and cancer, increasing healthcare expenditure in the region, and the presence of key vendors in the region. Several key vendors of the market, including Danaher, Thermo Fisher, General Electric, and Corning, have their headquarters in North America, which drives the market. These companies are significantly investing in the R&D and establishment of new manufacturing facilities with well-equipped cell culture processing units. For instance, in October 2019, Thermo Fisher Scientific introduced the first culture media that can remain stable when stored at room temperature. Similarly, in December 2019, Thermo Fisher established a USD 90 million viral vector manufacturing facility in Massachusetts, US. Such expansions will increase the product offerings by companies and their visibility in the region, as well as drive the demand for cell culture consumables.

Additionally, market research on stem cells and cancer, owing to the increasing incidences of cancer in the region, is also driving the market growth. The growing number of cancer cases fuels the need for cell-based therapies and vaccines, which, in turn, increases the demand for these consumables required in their preparation. The increasing incidences of cancer in the region also lead to an increase in healthcare expenditure. For instance, according to the Centers for Medicare and Medicaid Services (CMS), US healthcare spending grew by 2.7% in 2021. Furthermore, in 2019, the FDA and the US Department of Agriculture (USDA) announced their first formal agreement to regulate cell-cultured food products that are derived from the cells of poultry and livestock. With the increasing focus on research, technological advances in this technology are expected to increase, which will, in turn, drive the market in the US. Therefore, all the above-mentioned factors are expected to drive the market in North America during the forecast period.

Market Dynamics and Customer Landscape

The market is driven by the increasing demand for monoclonal antibodies in treating chronic diseases, including cancer. Biopharmaceutical and biotechnology companies, such as Danaher, Thermo Fisher, General Electric, and Corning, are key players in the market. Industry trend analysis, market pricing, and patent analysis play a crucial role in shaping market dynamics. Conference and webinar materials provide valuable insights for key stakeholders to understand buying behavior and secure funding for cell-based research. Cell culture technologies are advancing rapidly, creating opportunities for growth in the cell culture consumables market. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.

Key Market Driver

The growing demand for monoclonal antibodies is notably driving market growth. Monoclonal antibodies are synthetic immune cells produced in laboratories to substitute antibodies, fueling the biopharmaceutical and biotechnology sectors. They find extensive use in research, diagnostics, and immunotherapy across various fields, including medicine, biochemistry, and diagnostic imaging. These antibodies are pivotal in treating diseases like cancer, psoriasis, rheumatoid arthritis, and Crohn's disease. Large-scale manufacturing facilities, utilizing batch, continuous, and perfusion culture methods, drive global market growth. For example, Lonza's facility in Singapore boasts a range of mammalian bioreactors, contributing to market expansion alongside other key players like Danaher, Thermo Fisher, and General Electric. This trend is expected to persist, driven by industry trend analysis, market demand, and cell-based research advancements.

Significant Market Trends

Advances in cell culture media formulation and development are emerging trends in the market. There have been several advances in the formulation and development of culture media. One trend that is gaining prominence in the market is the elimination of animal-origin components in the development of cell culture media. This has resolved many shortcomings of the early formulations and has facilitated the development of a number of highly successful alternatives. For instance, the use of serum-free and chemically defined media for bioproduction has led to a reduction in batch-to-batch variability. Most biopharmaceutical manufacturing companies have switched to serum-free media and chemically defined media to reduce the risk of variation during manufacturing processes. 

Additionally, the focus is also shifting toward the development of more specified media instead of all-purpose media. The development of customized media formulations is aimed at maximizing the precise needs of end-users. The requirement of highly individualized processes will result in the diversification of cell culture media and create the need for further optimization around a specific protocol or process. Thus, the advances in these media formulation and development are likely to positively impact the growth of the market during the forecast period.

Major Market Challenge

The high risk of cell culture contamination is a major challenge impeding the market growth. Although these consumables are produced in a highly sterile and safe environment, there is still a high risk of contamination. The contamination can occur due to impurities in the media, sera, water, endotoxins, detergents, and plasticizers during production. They are prone to various forms of contamination, including chemical, biological, and cross-contamination. Chemical contamination of these includes adulteration of media, presence of improperly purified water, production of endotoxins by gram-negative bacteria, generation of free radicals due to the exposure of media to fluorescent lights, and plasticizers from plastic storage and tubing.  Contamination can also occur due to the presence of impurities in gases used in CO2 incubators, as well as detergents and disinfectants that are left in the equipment.

Additionally, biological culture contamination can occur due to adulteration by yeast, bacteria, viruses, moulds, protozoa, invertebrates, and mycoplasmas. Bacteria and fungi are virtually present everywhere and can quickly colonize and flourish in cell cultures. Moreover, viral contamination is difficult to detect as viruses are small and difficult to eliminate from media. Cross-contamination can occur due to infection from one cell line to another or due to the lack of aseptic conditions while obtaining cell lines from cell banks. The contamination of cell culture consumables can lead to significant financial losses for vendors. Therefore, such factors will impede the growth of the market during the forecast period.

Key Market Customer Landscape

The market report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.

Global Market Customer Landscape

Who are the Major Cell Culture Consumables Market Companies?

Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.

Euroclone SpA - The company specializes in a single segment and provides a range of products including cell biology, lab equipment, LAL test, molecular biology, laparoscopy, and more. Their primary focus is on the production of cell culture consumables.

The report also includes detailed analyses of the competitive landscape of the market and information about 15 market players, including:

• Agilent Technologies Inc.
• Corning Inc.
• Danaher Corp.
• Eppendorf SE
• General Electric Co.
• HiMedia Laboratories Pvt. Ltd.
• InvivoGen Corp.
• Lonza Group Ltd.
• Merck KGaA
• PromoCell GmbH
• Sartorius AG
• Thermo Fisher Scientific Inc.
• Becton Dickinson and Co.
• LGC Ltd.
• Standard BioTools Inc.

Qualitative and quantitative analysis of vendors has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize vendors as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize vendors as dominant, leading, robust, tentative, and weak.

Segment Overview

The market report forecasts market growth by revenue at global, regional & country levels and analyzes the latest trends and growth opportunities from 2017 to 2027. 

• Application Outlook 
  • Biopharmaceutical production
  • Cancer research
  • Others

• Region Outlook 
  • North America
    • The U.S.
    • Canada
  • Europe
    • The U.K.
    • Germany
    • France
    • Rest of Europe
  • Asia
    • China
    • India
    • Vietnam
    • Others
  • Rest of World
    • Saudi Arabia
    • South Africa
    • Brazil
    • Others

Market Analyst Overview

The market is driven by advancements in 2D cell cultures and 3D cell cultures, offering biopharmaceutical manufacturers innovative solutions. Accessories like autoclaves and biosafety cabinets ensure a safe environment. Advanced technologies like cell counters and cell debris formation analysis improve efficiency. Cell factory systems/cell stacks enhance cell yield, crucial for cell-based vaccines. Capital investment in these technologies is essential for the biopharmaceutical sector.

The market addresses challenges like plastic waste through recycling efforts. It supports preclinical/clinical research with production volumes and batches. Refrigerators & freezers are crucial for storage equipment, ensuring regulatory guidelines compliance. Roller/roux bottles aid in regenerative medicine research. Sera, media, and reagents are essential for stem cell therapy. Single-use bioprocessing systems and single-use bioreactors provide efficient solutions in limited space while ensuring sterilization. The market also includes supporting equipment for various research needs.

The market offers carbon dioxide incubators for optimal cell growth. Centrifuges aid in cell separation and analysis. Changeovers between cultures are facilitated by multiwell plates and flasks. While conventional bioreactors are used, there are limitations in producing high-density cell cultures. Corning Incorporated provides various consumables. Cryostorage systems ensure cell viability. Disposal of plastic consumables considers the environmental impact. Emerging economies drive market growth. Filtration systems prevent cross-contamination risk. Microcarriers support the growth. Microscopes are essential for observation. Petri dishes are used for various applications.

Cell Culture Consumables Market Scope
Report Coverage	Details
Page number	154
Base year	2022
Historic period	2017-2021
Forecast period	2023-2027
Growth momentum & CAGR	Accelerate at a CAGR of 22.3%
Market growth 2023-2027	USD 23.73 billion
Market structure	Fragmented
YoY growth 2022-2023(%)	21.6
Regional analysis	North America, Europe, Asia, and Rest of World (ROW)
Performing market contribution	North America at 46%
Key countries	US, Germany, UK, China, and Japan
Competitive landscape	Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks
Key companies profiled	Agilent Technologies Inc., Corning Inc., Danaher Corp., Eppendorf SE, Euroclone SpA, General Electric Co., HiMedia Laboratories Pvt. Ltd., InvivoGen Corp., Lonza Group Ltd., Merck KGaA, PromoCell GmbH, Sartorius AG, Thermo Fisher Scientific Inc., Becton Dickinson and Co., Bio Techne Corp., LGC Ltd., Standard BioTools Inc., Tecan Trading AG, FUJIFILM Corp., and Miltenyi Biotec B.V. and Co. KG
Market dynamics	Parent market analysis, Market Forecasting, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period.
Customization purview	If our market report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

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What are the Key Data Covered in this Market Research Report?

• CAGR of the market during the forecast period
• Detailed information on factors that will drive the market growth and forecasting of the market between 2023 and 2027
• Precise estimation of the size of the market size and its contribution to the parent market
• Accurate predictions about upcoming market trends and analysis and changes in consumer behavior
• Growth of the market industry across Europe, North America, APAC, South America, and Middle East and Africa
• Thorough market growth analysis of the market’s competitive landscape and detailed information about companies
• Comprehensive market analysis and report on the factors that will challenge the market research and growth of market companies

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