Pulmonary Arterial Hypertension - A Pipeline Analysis Report
Published: Jun 2018 | Pages: 179 | SKU: IRTNTR22379 |
Overview of the drug development pipeline for pulmonary arterial hypertension
PAH, a specific type of pulmonary hypertension, occurs due to scarred tissue in small pulmonary arteries that reduces the diameter of the arteries and results in high blood pressure in lungs. With the accumulation of scarred tissue, the right side of the heart needs to pump blood faster and will overwork. This overworking of the heart may be consequent in heart failure. According to report, almost 44.9% of patients in the UK underwent treatment for PAH in several pulmonary hypertension centers. Technavio’s market research analysts have predicted that with the introduction and development of strategies such as IPAH and APAH to treat pulmonary arterial hypertension, the global pulmonary arterial hypertension market will witness growth in the forthcoming years.
According to this pipeline analysis report, most of the drug development molecules in the pipeline are under the pre-clinical drug development stage. Our market research analysts have also identified that significant amount of drug molecules are under the phase I/II and phase II drug development stage. The pipeline landscape in the pipeline analysis report also mentions the percentage of drug development molecules that are in the phase I stage and several discontinued molecules.
Companies covered
This pipeline analysis report provides a detailed analysis of the companies that are involved in the development of drug development molecules for the treatment of PAH. In addition to providing information on the various stages of molecules developed by companies for different indications, this pipeline analysis report also provides information about the drug development molecules discontinued by companies.
Some of the companies covered in this pipeline analysis report are:
- ACCELERON PHARMA
- ARENA PHARMACEUTICALS
- GALECTIN THERAPEUTICS
- GLAXOSMITHKLINE
Therapeutic assessment of the drug development pipeline for pulmonary arterial hypertension by route of administration
- Oral
- Intravenous (IV)
- Subcutaneous
- Inhalation
- IV+subcutaneous
- Transdermal
The oral route of administration (ROA) involves the administration of drug substances through mouth cavity. It has been observed that the majority of total therapeutics are being developed for oral administration
Therapeutic assessment of the drug development pipeline for pulmonary arterial hypertension by therapeutic modalities
- Small molecule
- Biological
- Recombinant fusion protein
- Monoclonal antibody
According to this pipeline analysis report, majority of the molecules in the drug development pipeline for pulmonary arterial hypertension are being developed as small molecules. These molecules are chemically manufactured active substances that bind with specific biological macromolecules and act as an effector and alter the activity of the target cell. The low molecular weight of these molecules enables them to enter the body easily.
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PART 01: EXECUTIVE SUMMARY
PART 02: SCOPE OF THE REPORT
PART 03: RESEARCH METHODOLOGY
PART 04: INTRODUCTION
PART 05: MAJOR REGULATORY AUTHORITIES
- US
- Europe
- China
PART 06: PIPELINE LANDSCAPE
PART 07: COMPARATIVE ANALYSIS
- Discovery stage molecules
- Pre-clinical stage molecules
- Inactive and discontinued molecules
PART 08: INDICATION ANALYSIS
PART 09: THERAPEUTIC ASSESSMENT (THERAPY BASED)
PART 10: THERAPEUTIC ASSESSMENT (ROA BASED)
PART 11: THERAPEUTIC ASSESSMENT BY TARGET
PART 12: KEY COMPANIES
- Active companies: Category and parameters
PART 13: APPENDIX
- List of abbreviations
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
- Manufacturers and suppliers
- Channel partners
- Industry experts
- Strategic decision makers
Secondary sources
- Industry journals and periodicals
- Government data
- Financial reports of key industry players
- Historical data
- Press releases
DATA ANALYSIS
Data Synthesis
- Collation of data
- Estimation of key figures
- Analysis of derived insights
Data Validation
- Triangulation with data models
- Reference against proprietary databases
- Corroboration with industry experts
REPORT WRITING
Qualitative
- Market drivers
- Market challenges
- Market trends
- Five forces analysis
Quantitative
- Market size and forecast
- Market segmentation
- Geographical insights
- Competitive landscape
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Key Questions Answered
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- Who are the key market vendors and their growth strategies?
- What are the latest trends influencing the growth of this market?
- What are the variables influencing the market growth in the primary regions?
- What are the factors influencing the growth of the parent market?
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