Chromatography Resins Market by Technique, Application, and Geography - Forecast and Analysis 2021-2025

The chromatography resins market share is expected to increase by USD 1.21 billion from 2020 to 2025, and the market's growth momentum will accelerate at a CAGR of 8.95%.

This chromatography resins market research report provides valuable insights on the post-COVID-19 impact on the market, which will help companies evaluate their business approaches. Furthermore, this report extensively covers chromatography resins market segmentation by technique (affinity, ion exchange, hydrophobic interaction, size exclusion, and multimodal), application (pharmaceutical and biotechnology, food and beverages, drug discovery, diagnostics and analytical, and others), and geography (North America, APAC, Europe, MEA, and South America). The chromatography resins market report also offers information on several market vendors, including Avantor Inc., Bio-Rad Laboratories Inc., Danaher Corp., DuPont de Nemours Inc., Merck KGaA, Mitsubishi Chemical Holdings Corp., PerkinElmer Inc., Repligen Corp., Sartorius AG, and Thermo Fisher Scientific Inc. among others.

What will the Chromatography Resins Market Size be During the Forecast Period?

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Chromatography Resins Market: Key Drivers, Trends, and Challenges

Based on our research output, there has been a neutral impact on the market growth during and post COVID-19 era. The increasing r&d in biopharmaceuticals is notably driving the chromatography resins market growth, although factors such as the high price of affinity chromatography resin may impede the market growth. Our research analysts have studied the historical data and deduced the key market drivers and the COVID-19 pandemic impact on the chromatography resins market industry. The holistic analysis of the drivers will help in deducing end goals and refining marketing strategies to gain a competitive edge.

Key Chromatography Resins Market Driver

One of the key factors driving the data center market is the increasing R&D in biopharmaceuticals. Chromatography plays a crucial role in the purification of biopharmaceuticals. It is also held accountable for a considerable portion of downstream processing efforts, which involve time and cost. Therefore, there is consistent pressure to improve the productivity and efficiency of the process. Several developments in large-scale chromatography processes have been witnessed in the market, including the development of new resin properties, such as enhancing Protein A for use in capturing mAb, implementing single-use technologies, and exploring the continuous potential of chromatography on a commercial scale, and the increasing use of automation. Furthermore, a new platform technology based on affinity chromatography resins has been introduced by Thermo Fisher Scientific, focusing on large-scale production capability. This new platform is intended to address challenges in the purification of mAbs, blood factors, antibody fragments, gene therapy vectors, and viral vaccines. The new affinity resins are effective for small antibody fragments, new antibody types, and fusion proteins, whereas Protein A chromatography is ineffective due to their binding with other portions of immunoglobin G. Protein A is still used in chromatography to purify standard mAbs from solutions. Furthermore, the high cost of this purification process keeps the improvement of Protein A resin's performance always in focus.

Key Chromatography Resins Market Trend

The rising number of CROs and CMOs in the pharmaceutical and biotechnology industries is another factor supporting the data center market growth in the forecast period. Pharmaceutical companies are witnessing globalization. The globally converging quality standards lead to more documentation, cost, and time for the manufacturers. Being a tightly regulated industry, it is important for pharmaceutical companies to comply with the rules and regulations. Furthermore, pharmaceutical companies are outsourcing to eliminate the risk of development. Companies form strategic alliances with CROs and CMOs, which are paid in the form of shares, royalties, or milestone payments. Over the past few years, in-house processes have been outsourced to external providers, and the number of CROs and CMOs has been increasing because of the growing demands from the biotechnology and pharmaceutical industries. Moreover, outsourcing the processes to CROs and CMOs helps pharmaceutical companies access expertise and specialist knowledge that is not available in-house, therefore avoiding or lowering costs and minimizing investments. The rise in integrated partnerships proves to be beneficial in shortening the new drug development time, thus simplifying the supply chain from preclinical to commercial supply and reducing the time-to-market. This also proves favorable for pharmaceutical and biotechnology companies as they are able to focus on their core business.

Key Chromatography Resins Market Challenge

The high price of affinity chromatography resin will be a major challenge for the data center market during the forecast period. The chromatography technique consists of capturing and refining desired molecules and the removal of impurities and aggregates arising from host cells. In bioprocessing, chromatography is the main operational unit. However, it also has major downstream bottlenecks because of the usage of costly chromatographic resins. Affinity chromatography resin is still the most commonly used resin used during the capture step that is capable of achieving high purity, selectivity, and yield. Based on the biophysical properties of the target protein, the types of affinity ligands used vary. Affinity adsorbents were previously based on biospecific or biological ligands such as enzymes, lectins, immunoglobulins, and bacterial proteins. This was until camelid-derived single-domain antibody fragments and engineered antibodies like affibodies were developed recently. These limitations are mainly connected to the production cost, toxicity, and low stability during cleaning-in-place and sterilization-in-place treatments and lot-to-lot variability of biomolecules. This has led to the emergence of reasonably priced synthetic pseudo-biospecific affinity ligands such as hydrophobic ligands, immobilized metals, dyes, and biomimetic ligands. Furthermore, other affinity approaches such as continuous chromatography, expanded-bed chromatography, and monolithic chromatography are being applied to reduce bioprocessing costs and downstream steps.

This chromatography resins market analysis report also provides detailed information on other upcoming trends and challenges that will have a far-reaching effect on the market growth. The actionable insights on the trends and challenges will help companies evaluate and develop growth strategies for 2021-2025.

Parent Market Analysis

Technavio categorizes the global chromatography resins market as a part of the global specialty chemicals market. Our research report has extensively covered external factors influencing the parent market growth potential in the coming years, which will determine the levels of growth of the chromatography resins market during the forecast period.

Who are the Major Chromatography Resins Market Vendors?

The report analyzes the market's competitive landscape and offers information on several market vendors, including:

 

• Avantor Inc.
• Bio-Rad Laboratories Inc.
• Danaher Corp.
• DuPont de Nemours Inc.
• Merck KGaA
• Mitsubishi Chemical Holdings Corp.
• PerkinElmer Inc.
• Repligen Corp.
• Sartorius AG
• Thermo Fisher Scientific Inc.

 

This statistical study of the chromatography resins market encompasses successful business strategies deployed by the key vendors. The chromatography resins market is concentrated and the vendors are deploying growth strategies such as developing high-quality products for various end-users, including the food and beverage and pharmaceutical industries, and increase in investment in R&D for drug discovery to compete in the market.

Product Insights and News

• Avantor Inc. - The company offers chromatography resins under the brand J.T.Baker as J.T.Baker BAKERBOND PROchievA.
• Mitsubishi Chemical Holdings Corp. - The company offers the DIAION HP20SS series SEPABEADS SP20SS series which is capable of advanced separation and purification in chromatographic separation.

To make the most of the opportunities and recover from the post-COVID-19 impact, market vendors should focus more on the growth prospects in the fast-growing segments, while maintaining their positions in the slow-growing segments.

The chromatography resins market forecast report offers in-depth insights into key vendor profiles. The profiles include information on the production, sustainability, and prospects of the leading companies.

Chromatography Resins Market Value Chain Analysis

Our report provides extensive information on the value chain analysis for the chromatography resins market, which vendors can leverage to gain a competitive advantage during the forecast period. The end-to-end understanding of the value chain is essential in profit margin optimization and evaluation of business strategies. The data available in our value chain analysis segment can help vendors drive costs and enhance customer services during the forecast period.

The value chain of the global specialty chemicals market includes the following core components:

• Inputs
• Inbound logistics
• Operations
• Outbound logistics
• Marketing and sales
• Service
• Support activities
• Innovation

The report has further elucidated other innovative approaches being followed by manufacturer providers to ensure a sustainable market presence.

 

Which are the Key Regions for Chromatography Resins Market?

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41% of the market's growth will originate from North America during the forecast period. The US is the key market for the chromatography resins market in North America. Market growth in this region will be faster than the growth of the market in other regions.

The ever-increasing demand for pharmaceutical drugs and products, along with the growth of the food and beverages market will facilitate the chromatography resins market growth in North America over the forecast period. This market research report entails detailed information on the competitive intelligence, marketing gaps, and regional opportunities in store for vendors, which will assist in creating efficient business plans.

COVID Impact and Recovery Analysis

The outbreak of COVID-19 affected all the countries in North America, especially the US. The rise in the number of COVID-19 cases during the second wave of the pandemic in the first half of 2021 led to the re-imposition of partial lockdowns in several countries, including the US, Canada, and Mexico. In addition, most manufacturing units for non-essential and non-urgent products, including those related to specialty chemicals, were closed or operating at a lower production capacity as per the government's guidelines. These measures negatively affected the growth of the chromatography resins market in the region in 2020, and the impact is expected to continue in 2021 as well. However, with the resumption of normal business activities, along with the various disease containment measures in place, the chromatography resins market in North America is expected to stabilize in late 2021. The market is also expected to register accelerating growth during the latter half of the forecast period.

What are the Revenue-generating Technique Segments in the Chromatography Resins Market?

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The chromatography resins market share growth by the affinity segments. The affinity segment will be significant during the forecast period. Affinity chromatography is the most powerful of all other chromatography methods as it offers high selectivity, high capacity, and high resolution. Reversible interactions can be biospecific, such as antibodies binding to protein A, or non-bispecific such as histidine-tagged proteins bound to metal ions during the process of immobilized metal ion affinity chromatography (IMAC).

This report provides an accurate prediction of the contribution of all the segments to the growth of the chromatography resins market size and actionable market insights on the post-COVID-19 impact on each segment.

 

Chromatography Resins Market Scope
Report Coverage	Details
Page number	120
Base year	2020
Forecast period	2021-2025
Growth momentum & CAGR	Accelerate at a CAGR of 8.95%
Market growth 2021-2025	$ 1.21 billion
Market structure	Concentrated
YoY growth (%)	8.57
Regional analysis	North America, APAC, Europe, MEA, South America, and
Performing market contribution	North America at 41%
Key consumer countries	US, China, Japan, Germany, and Canada
Competitive landscape	Leading companies, Competitive strategies, Consumer engagement scope
Key companies profiled	Avantor Inc., Bio-Rad Laboratories Inc., Danaher Corp., DuPont de Nemours Inc., Merck KGaA, Mitsubishi Chemical Holdings Corp., PerkinElmer Inc., Repligen Corp., Sartorius AG, and Thermo Fisher Scientific Inc.
Market dynamics	Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period
Customization purview	If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

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What are the Key Data Covered in this Chromatography Resins Market Report?

• CAGR of the market during the forecast period 2021-2025
• Detailed information on factors that will drive chromatography resins market growth during the next five years
• Precise estimation of the chromatography resins market size and its contribution to the parent market
• Accurate predictions on upcoming trends and changes in consumer behavior
• The growth of the chromatography resins industry across North America, APAC, Europe, MEA, and South America
• A thorough analysis of the market's competitive landscape and detailed information on vendors
• Comprehensive details of factors that will challenge the growth of chromatography resins market vendors

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