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The freeze drying equipment market size is estimated to grow by USD 3,061.95 million accelerating at a CAGR of 9.01% between 2023 and 2027. This freeze-drying equipment market report extensively covers market segmentation by Product (tray style, manifold, and rotary), Application (biotechnology, food processing, pharmaceuticals, surgical procedures, and others), and Geography (Europe, APAC, North America, South America, and Middle East and Africa). It also includes an in-depth analysis of drivers, trends, and challenges. Furthermore, the report includes historic market data from 2017 to 2021.
Report Coverage |
Details |
Page number |
163 |
Base year |
2022 |
Historic period |
2017-2021 |
Forecast period |
2023-2027 |
Growth momentum & CAGR |
Accelerate at a CAGR of 9.01% |
Market growth 2023-2027 |
USD 3061.95 million |
Market YoY |
Fragmented |
YoY growth 2022-2023(%) |
8.58 |
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Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
The market growth is being driven significantly by the benefits of freeze-drying over conventional drying. This technology has been utilized for more than three decades to stabilize various chemical components and is gaining increasing usage in the pharmaceutical and biotechnology industries due to its potential advantages over conventional drying methods such as crystallization, filtration, and precipitation.
The primary benefit of freeze-drying over conventional drying is the preservation of the chemical and biological potency and homogeneity of the final products. Furthermore, freeze-drying allows for easy dispensing and metering before final packaging, as well as protection against solution effects and chemical degradation. Compared to dry powder fills, freeze-drying can also increase the speed of rehydration. Additionally, freeze-dried products can remain in their original state for years in appropriate packaging and storage conditions due to their low moisture content.
In contrast, conventionally dried products have a higher moisture content than freeze-dried products, which makes them a breeding ground for mold and organisms. Consequently, conventionally dried products have a shorter shelf life than freeze-dried products. Moreover, freeze-drying allows samples to dry in their original containers, reducing the risk of altering their initial state. Thus, these benefits are likely to fuel the growth of the market during the forecast period.
The market is witnessing an emerging trend of smart freeze dryers. Companies are investing in research and development to achieve cost synergies and optimize processes to increase efficiency, lower operating costs, and reduce emissions. As remote monitoring technologies become more widely adopted for optimized results, the freeze-drying industry is following suit.
Vendors in the market have introduced smart freeze dryers, which offer increased reliability and affordability. These dryers are based on standardized modules and are designed to meet the specific size and technology requirements of each customer. In addition to being cost-effective, these dryers also facilitate planning, validation, and documentation, significantly reducing delivery times. These factors are expected to drive the adoption of smart freeze dryers, thereby driving the market growth during the forecast period.
The market growth is being impeded by the emergence of potential alternatives to freeze-drying. Various methods such as spray drying, spray freeze-drying, atmospheric spray freeze-drying, and vacuum foam drying have emerged as potential alternatives to freeze-drying for producing dry formations of biopharmaceuticals. Among these, spray freeze-drying has gained popularity in recent years and has emerged as the most mature alternative to lyophilization. In spray freeze-drying, the sublimation and secondary drying of frozen particles are faster than those in conventional freeze-drying due to the increased surface area of the frozen starting material. Additionally, it allows for the engineering of particle size and shape, enabling delivery methods that are infeasible with other drying techniques. Furthermore, it can process materials under atmospheric pressure and offers energy savings.
Vacuum foam drying has also emerged as a potential approach in recent years for preserving sensitive biological materials. It is a short, simple, and industrially economical process for preserving biologics, which can offer better processing and storage stability to products such as bovine serum albumin compared to freeze-drying. Hence, the growing popularity of such alternatives is expected to constrain the growth of the global market during the forecast period.
The tray-style segment was valued at USD 2,419.30 million in 2017 and continued to grow until 2021. Tray-style freeze dryers are known to be more advanced and larger in size when compared to manifold freeze dryers. The primary benefit of tray-style freeze dryers is that they allow products to freeze in place and perform both primary and secondary freeze-drying, leading to the driest possible final product. Moreover, they can handle bulk products as well as vials/containers for the freeze-drying process. When drying vials, tray-style freeze dryers are equipped with a stoppering mechanism that allows a stopper to be placed in the dryer, ensuring the vial is sealed before it is exposed to the atmosphere. Thus, tray-style freeze dryers are increasingly being utilized for the long-term preservation of vaccines. Given these advantages, this segment of the market is anticipated to experience growth during the forecast period.
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Freeze-drying equipment is dominating the market under the application segment. In the healthcare industry, freeze-drying equipment is used by biotechnology companies for the preservation and stabilization of various biological products, such as antibodies, proteins, peptides, vaccines, nucleic acids, antibody-drug conjugates, biological tissue samples, human red blood cells, platelets, serum/plasma, and microorganisms. The developments in the field of biotechnology are increasing, and there are many dedicated biotechnology firms globally that provide services such as R and D, bioinformatics, gene identification, and stem cell databank storage. Many biotechnology companies are investing extensively in cell-based therapies and biobanks to develop new drugs for the treatment of chronic and rare diseases. The rise in the number of biobanks will fuel the demand for freeze-drying equipment during the forecast period for the preservation of biological specimens.
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Europe is estimated to contribute 39% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
Europe's main revenue contributors to the market are the UK and Germany. The demand for freeze-drying equipment in the region is primarily driven by the extensive focus of various pharmaceutical companies, including Novartis and Sanofi, on developing novel drugs and vaccines, and the increasing number of cancer biomarker studies, as freeze-drying provides high storage stability for labile biomolecules in drugs and vaccines.
The high pharmaceutical spending in the region has resulted in increased drug consumption, which is positively impacting the demand for lyophilization. For example, Switzerland, Belgium, and Germany were the leading countries in Europe in terms of per capita pharmaceutical spending in 2020, as per the OECD. As a result, the growing number of biopharmaceutical clinical trials and the increase in pharmaceutical spending is driving the demand for freeze-drying equipment in Europe during the forecast period.
The outbreak of COVID-19 had a moderate impact on the market in Europe in 2020 due to a reduction in the purchase of packaged food products and biopharmaceuticals that are processed or stored using freeze-drying equipment. However, in 2021, most of the lockdowns were lifted, and production activities resumed owing to the large-scale COVID-19 vaccination programs conducted across Europe. Thus, the demand for freeze-drying equipment is anticipated to grow in the region during the forecast period.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.
Gevasol- The company offers Gevasol fluid control, Gevasol motion control, and Gevasol vacuum systems.
The research report also includes detailed analyses of the competitive landscape of the market and information about 15 market companies, including:
ATS Automation Tooling Systems Inc., Azbil Corp., Biopharma Process Systems Ltd., BUCHI Labortechnik AG, Cuddon Freeze Dry, GEA Group AG, Gem Machinery and Allied Industries, Gevasol, HOF Sonderanlagenbau GmbH, IMA Industria Macchine Automatiche Spa, Labconco Corp., Lyophilization Systems India Pvt Ltd., Martin Christ Gefriertrocknungsanlagen GmbH, MechaTech Systems Ltd., Millrock Technology Inc., OPTIMA packaging group GmbH, Scala Scientific BV, Shanghai Tofflon Science and Technology Co. Ltd., ZIRBUS technology GmbH, and Freeze Drying Systems Pvt. Ltd.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The freeze drying equipment market report forecasts market growth by revenue at global, regional & country levels and provides an analysis of the latest trends and growth opportunities from 2017 to 2027.
Freeze Drying Equipment Market Report |
|
Report Attributes |
Details |
Regional analysis |
Europe, APAC, North America, South America, and Middle East and Africa |
Performing market contribution |
Europe at 39% |
Key countries |
US, China, Japan, UK, and Germany |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
ATS Automation Tooling Systems Inc., Azbil Corp., Biopharma Process Systems Ltd., BUCHI Labortechnik AG, Cuddon Freeze Dry, GEA Group AG, Gem Machinery and Allied Industries, Gevasol, HOF Sonderanlagenbau GmbH, IMA Industria Macchine Automatiche Spa, Labconco Corp., Lyophilization Systems India Pvt Ltd., Martin Christ Gefriertrocknungsanlagen GmbH, MechaTech Systems Ltd., Millrock Technology Inc., OPTIMA packaging group GmbH, Scala Scientific BV, Shanghai Tofflon Science and Technology Co. Ltd., ZIRBUS technology GmbH, and Freeze Drying Systems Pvt. Ltd. |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Product
7 Market Segmentation by Application
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
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