ALK Inhibitors for Non-Small Cell Lung Cancer (NSCLC) - A Pipeline Analysis Report
- Published: Jul 2018
- Pages: 85
- SKU: IRTNTR23003
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This pipeline analysis report provides detailed insights into the clinical trials landscape of the drug development for ALK inhibitors for non-small cell lung cancer including molecules at pre-clinical and discovery stage. The report also offers comprehensive information about the therapeutic assessment of the pipeline molecules based on various segmentations such as therapy, route of administration, and target.
Overview of the drug development for ALK inhibitors for NSCLC
It has been observed that NSCLC is one of the major type of lung cancer. It develops when lung cells start to grow uncontrollably. It can further be categorized into subtypes based on types of lung cells involved including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma, but they all are clustered together as NSCLC due to similar treatment and prognosis approach. The ALK fusion gene, which is a component in the lung cells, gets abnormally activated in NSCLC, which can further result in an uncontrolled cell growth. The ALK gene is fused to the EML4 gene in anaplastic lymphoma kinase-positive lung cancer. ALK+ lung cancer is not always associated with smoking and can be developed in non-smokers also. According to the NIH, lung cancer is the most common type of cancer responsible for deaths in both men and women in the US. NSCLC accounts for more than 85% of all lung cancers. Furthermore, according to CDC, lung cancer is the leading cause of cancer mortality and the second most diagnosed cancer in both men and women in the US. Consequently, the rising incidences of NSCLC is further expected to promote the drug development for ALK inhibitors for NSCLC.
According to this pipeline analysis report, most of the drug development molecules in the pipeline are being developed for NSCLC. Our market research analysts have also identified that most of these molecules are in the pre-clinical development stage and a considerable number of molecules have been discontinued from development.
Companies covered
This pipeline analysis report provides a detailed analysis of the companies that are involved in the development of gene therapy molecules for the treatment of NSCLC. In addition to providing information on the various stages of molecules developed by companies for different indications, this pipeline analysis report also provides information about the gene therapy molecules discontinued by companies.
Some of the companies covered in this pipeline analysis report are –
- Igyta
- Pfizer
- Xcovery
Therapeutic assessment of the drug development pipeline for ALK inhibitors for NSCLC by route of administration
- Oral
The oral route of administration (ROA) involves the application of the drug directly through the mouth cavity, which will have a more direct effect on the target cells.
Therapeutic assessment of the drug development pipeline for ALK inhibitors for NSCLC for AMD by therapy
- Monotherapy
- Combination therapy
According to this pipeline analysis report, many of the molecules that are currently in the drug development for ALK inhibitors for NSCLC are being developed as monotherapy drugs and most of these molecules are in the pre-clinical stage of development.
Key questions answered in the report include
- What are the drug development molecules in the various development stages for ALK inhibitors for NSCLC?
- What are the companies that are currently involved in the drug development for ALK inhibitors for NSCLC?
- Insight into discontinued/inactive molecules with appropriate reasoning?
- What are the major regulatory authorities approving drugs in various regions?
- Detailed profiling of each active molecule
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PART 01: EXECUTIVE SUMMARY
PART 02: SCOPE OF THE REPORT
PART 03: RESEARCH METHODOLOGY
PART 04: INTRODUCTION
PART 05: MAJOR REGULATORY AUTHORITIES
- US
- Europe
- China
PART 06: PIPELINE LANDSCAPE
PART 07: COMPARATIVE ANALYSIS
- Discovery stage molecules
- Pre-clinical stage molecules
- Inactive and discontinued molecules
PART 08: INDICATION ANALYSIS
PART 09: THERAPEUTIC ASSESSMENT (THERAPY BASED)
PART 10: THERAPEUTIC ASSESSMENT (ROA BASED)
PART 11: THERAPEUTIC ASSESSMENT BY TARGET
PART 12: KEY COMPANIES
- Active companies: Category and parameters
PART 13: APPENDIX
- List of abbreviations
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
- Manufacturers and suppliers
- Channel partners
- Industry experts
- Strategic decision makers
Secondary sources
- Industry journals and periodicals
- Government data
- Financial reports of key industry players
- Historical data
- Press releases

DATA ANALYSIS
Data Synthesis
- Collation of data
- Estimation of key figures
- Analysis of derived insights
Data Validation
- Triangulation with data models
- Reference against proprietary databases
- Corroboration with industry experts

REPORT WRITING
Qualitative
- Market drivers
- Market challenges
- Market trends
- Five forces analysis
Quantitative
- Market size and forecast
- Market segmentation
- Geographical insights
- Competitive landscape
Key Questions Answered
- What are the key global market and the regional market share?
- What are the revenue-generating key market segments?
- What are the key factors driving and challenging this market’s growth?
- Who are the key market vendors and their growth strategies?
- What are the latest trends influencing the growth of this market?
- What are the variables influencing the market growth in the primary regions?
- What are the factors influencing the growth of the parent market?
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