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The Affinity Chromatography Reagents Market size is estimated to grow by USD 478.16 million at a CAGR of 9.35% between 2022 and 2027.
There has been an increase in R&D in biopharmaceuticals and affinity chromatography plays an essential role in the purification of biopharmaceuticals. Some of the developments in the large-scale chromatography processes in the market are the development of new resin properties including improving Protein A for use in capturing mAb, implementing single-use technologies, exploring the continuous potential of chromatography on a commercial scale, and the growing use of automation. Furthermore, Thermo Fisher Scientific Inc. which focuses on large-scale production capability has launched a new platform technology based on affinity chromatography resins. Therefore, such developments are expected to positively impact the market growth.
Technavio has segmented the market into Application, End-user, and Geography
It also includes an in-depth analysis of drivers, trends, and challenges. Our report examines historic data from 2017 to 2021, besides analyzing the current market scenario.
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The analytical chromatography reagent segment is estimated to witness significant growth during the forecast period. Some of the key applications of analytical chromatography reagents include separation in industry and academia as well as quantitation and identification of chemical or biological compounds.
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The analytical chromatography reagent segment was the largest segment and was valued at USD 382.91 million in 2017. Additionally, the Analytical chromatography reagent segment is important in the manufacturing of pharmaceuticals, chemicals, or food and beverages. For example, Merck KGaA is a prominent market player in the market which provides analytical products including gas chromatography for pesticide residue testing and trace analysis. Hence, the wide application of the analytical reagents segment is expected to drive market growth during the forecast period.
There is an increasing focus by affinity chromatography reagent manufacturers on drug R&D, due to the various application of affinity chromatography in drug affinity screening and the isolation and purification of protein, amino acids, and antibodies with the help of different affinity media. Amino acid media, carbohydrate bonding media, and hydrophobic interaction media are some of the commonly used affinity media. There is increasing adoption of affinity chromatography across pharmaceutical and biotechnology product manufacturing in order to remove specific contaminants, achieve faster separation of complex molecules, and attain high-purity synthesis. Hence, such factors are expected to fuel the growth of this segment which, in turn, will drive the market growth during the forecast period.
One of the main applications of affinity chromatography reagents in the food and beverage industry is to detect and separate contaminants and toxic compounds from food products to ensure food safety. For instance, immunoaffinity chromatography is extensively utilized in food and beverage industries as it leverages a highly selective approach for the separation of a targeted compound using antibodies. Furthermore, other applications include the isolation and extraction of mycotoxins (fungal toxins) from contaminated food products. Hence, such factors are expected to fuel the growth of this segment which, in turn, will drive the market growth during the forecast period.
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North America is estimated to contribute 40% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that will shape the market during the forecast period. Some of the key factors which are significantly contributing to the global affinity chromatography reagents market in North America are the increasing focus on drug development and research, the rising approval of monoclonal antibody-based therapies, and the presence of many key affinity chromatography reagent manufacturers.
Additionally, there is increasing adoption of affinity chromatography reagents in the pharmaceutical and biotechnology sector due to the increasing approval of therapeutic monoclonal antibodies in the US. For instance, some of the therapeutic monoclonal antibodies approved by FDA include Polatuzumab vedotin (brand name: Polivy) offered by F. Hoffmann-La Roche Ltd., Risankizumab (brand name: Skyrizi) offered by AbbVie Inc., Romosozumab (brand name: Evenity) offered by Amgen Inc., and Caplacizumab (brand name: Cablivi) offered by Ablynx. Hence, such factors are expected to drive market growth in the region during the forecast period.
In 2020, during the COVID-19 pandemic, the growth of the global affinity chromatography reagents market witnessed a significant slowdown due to the closure of several manufacturing units for non-essential and non-urgent products, including those related to specialty chemicals in North America. However, in 2021, the initiation of large-scale vaccination drives lifted the lockdown and travel restrictions, which led to the resumption of normal business activities. Such factors are expected to drive the market during the forecast period.
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Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about 20 market companies, including:
Agilent Technologies Inc: The company offers affinity chromatography reagents such as filters for gel matrices.
AMS Biotechnology Europe Ltd., Avantor Inc., Bio Rad Laboratories Inc., Hamilton Bonaduz AG, Helena Laboratories Corp., Kaneka Corp., Kanto Chemical Co. Inc., Loba Chemie Pvt. Ltd., Merck KGaA, PerkinElmer Inc., Promega Corp., QIAGEN NV, Regis Technologies Inc., Santa Cruz Biotechnology Inc., Sartorius AG, Thermo Fisher Scientific Inc., Waters Corp., Shimadzu Corp., and Tosoh Corp.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
There are multiple factors influencing market growth. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges.
One of the key factors driving the market growth is the adoption of automation in affinity chromatography. The main issue associated with the manual procedures in protein purification and manufacturing techniques is that it is labor-intensive and time-consuming. Furthermore, several liquid chromatography-based systems are expensive and complex to learn. Therefore, many manufacturers are providing automated solutions for performing affinity chromatography.
The main advantage of such solutions is that it is less expensive and are easy to learn. AKTA Chromatography Systems by GE, Profinia Protein Purification System by Bio-Rad Laboratories, and AssayMAP Affinity Purification Solution by Agilent Technologies are some of the key solutions offered in the market. Hence, it has resulted in the emergence of fast, reliable, and cost-effective protein purification techniques that have high analytical precision and high quantitative recovery. which is expected to drive market growth during the forecast period.
A key factor shaping the affinity chromatography reagents market growth is the increasing focus on advanced, faster, and cost-effective purification technologies. An increase in the number of protein-based therapies has facilitated the development of cost-effective, faster, and efficient chromatographic workflow among end-users, including the pharmaceutical and biotechnology industries.
There is an increasing preference for products with short time-to-market among end-users as the protein therapeutics market is highly competitive. Furthermore, several market players are launching advanced reagents that have high binding capabilities and provide a reduction in time to perform the chromatography process when compared to traditional resins. Hence, such factors are expected to drive market growth during the forecast period.
The high cost of resins used in affinity chromatography is one of the key challenges hindering the market growth during the forecast period. The use of high-priced resins for lining the columns are significantly contributing to the overall cost of the affinity chromatography procedure. These resins typically comprise beaded agarose coupled with capturing proteins such as Protein A and G.
Furthermore, several advanced costs are approximately between USD 11,000 and USD 12,000 per liter. Additionally, entrapping resins used in affinity purification are utilized for protein synthesis and antibody manufacturing and the cost of this procedure can range from 25% to 30% of the overall cost. Hence, such factors are expected to hinder market growth during the forecast period.
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The market report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.
Global Affinity Chromatography Reagents Market Customer Landscape
The affinity chromatography reagents market report forecasts market growth by revenue at global, regional & country levels and provides an analysis of the latest trends and growth opportunities from 2017 to 2027.
Affinity Chromatography Reagents Market Scope |
|
Report Coverage |
Details |
Page number |
166 |
Base year |
2022 |
Historic period |
2017-2021 |
Forecast period |
2023-2027 |
Growth momentum & CAGR |
Accelerate at a CAGR of 9.35% |
Market growth 2023-2027 |
USD 478.16 million |
Market structure |
Fragmented |
YoY growth 2022-2023(%) |
8.87 |
Regional analysis |
North America, Europe, Asia, and the Rest of the World (ROW) |
Performing market contribution |
North America at 40% |
Key countries |
US, Germany, UK, China, and Japan |
Competitive landscape |
Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks |
Key companies profiled |
Agilent Technologies Inc., AMS Biotechnology Europe Ltd., Avantor Inc., Bio Rad Laboratories Inc., Hamilton Bonaduz AG, Helena Laboratories Corp., Kaneka Corp., Kanto Chemical Co. Inc., Loba Chemie Pvt. Ltd., Merck KGaA, PerkinElmer Inc., Promega Corp., QIAGEN NV, Regis Technologies Inc., Santa Cruz Biotechnology Inc., Sartorius AG, Thermo Fisher Scientific Inc., Waters Corp., Shimadzu Corp., and Tosoh Corp. |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for the forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Application
7 Market Segmentation by End-user
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
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