Hereditary Angioedema - A Pipeline Analysis Report
- Published: Apr 2018
- Pages: 82
- SKU: IRTNTR22694
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This pipeline analysis report provides detailed insights into the drug development landscape of the development of drug for hereditary angioedema including molecules at pre-clinical, discovery, and other developmental stages. The report also offers comprehensive information about the therapeutic assessment of the pipeline molecules based on various segmentations such as indications coverage, therapies employed, route of administration, therapeutic modality, targets for drug development, and mechanism of action.
Overview of the drug development pipeline for hereditary angioedema
Hereditary angioedema (HAE) is a genetic disorder and is also known as angioedema. It is resulted from low level of plasma protein C1 inhibitor that causes swelling of hand, skin, and feet. One out of 50,000 people are estimated to be affected by HAE, in which, Type III is very rare and accounts for 1%, Type II for 15%, and Type I for 84-85%. Patients suffering from this condition experience various symptoms including muscle aches, abdominal pain, problem in breathing, and headache and vomiting. Technavio’s market research analysts have predicted that with the introduction of prophylactic treatment as one of the most promising approach to treat hereditary angioedema, the global hereditary angioedema market will witness growth in the forthcoming years.
According to this pipeline analysis report, most of the drug development molecules in the pipeline are under the pre-clinical development stage. For instance, sponsors such as Adverum Biotechnologies developed ADVM-053 and Alnylam Pharmaceuticals developed ALN-F12, which are under the pre-clinical stage. Our market research analysts have also identified that a small amount of drug molecules that are being developed comes under the phase III, and phase II, and discovery stages. The pipeline landscape in the pipeline analysis report mentions the percentage of drug development molecules that are under the phase I stage.
Companies covered
This pipeline analysis report provides a detailed analysis of the companies that are involved in the development of drug molecules for the treatment of hereditary angioedema. In addition to providing information on the various stages of molecules developed by companies for different indications, this pipeline analysis report also provides information about the drug development molecules discontinued by companies.
Some of the companies covered in this pipeline analysis report are –
- CEVEC
- CSL Behring
- Ionis Pharmaceuticals
Therapeutic assessment of the drug development pipeline for hereditary angioedema by route of administration
- Subcutaneous
- Oral
- Intravenous
The subcutaneous route of administration (ROA) involves the administration of drug substances directly into the tissue layer between the skin and muscle mostly with a short needle. It has been observed that the majority of total therapeutics are being developed for subcutaneous administration.
Therapeutic assessment of the drug development pipeline for hereditary angioedema by therapeutic modality
- Biomolecule
- Small molecule
According to this pipeline analysis report, the majority of molecules that are currently in the drug development pipeline for hereditary angioedema are being developed as biomolecules. Biomolecule plays a significant role in the maintenance and metabolic processes of living organisms.
Key questions answered in the report include
- What are the drug development molecules in the various development stages for hereditary angioedema?
- What are the companies that are currently involved in the development of drug development molecules for hereditary angioedema?
- Insight into discontinued/inactive molecules with appropriate reasoning?
- What are the major regulatory authorities approving drugs in various regions?
- Detailed profiling of each active molecule
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PART 01: EXECUTIVE SUMMARY
PART 02: SCOPE OF THE REPORT
PART 03: RESEARCH METHODOLOGY
PART 04: INTRODUCTION
PART 05: MAJOR REGULATORY AUTHORITIES
- US
- Europe
- China
PART 06: PIPELINE LANDSCAPE
PART 07: COMPARATIVE ANALYSIS
- Discovery stage molecules
- Pre-clinical stage molecules
- Inactive and discontinued molecules
PART 08: INDICATION ANALYSIS
PART 09: THERAPEUTIC ASSESSMENT (THERAPY BASED)
PART 10: THERAPEUTIC ASSESSMENT (ROA BASED)
PART 11: THERAPEUTIC ASSESSMENT BY TARGET
PART 12: KEY COMPANIES
- Active companies: Category and parameters
PART 13: APPENDIX
- List of abbreviations
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
- Manufacturers and suppliers
- Channel partners
- Industry experts
- Strategic decision makers
Secondary sources
- Industry journals and periodicals
- Government data
- Financial reports of key industry players
- Historical data
- Press releases

DATA ANALYSIS
Data Synthesis
- Collation of data
- Estimation of key figures
- Analysis of derived insights
Data Validation
- Triangulation with data models
- Reference against proprietary databases
- Corroboration with industry experts

REPORT WRITING
Qualitative
- Market drivers
- Market challenges
- Market trends
- Five forces analysis
Quantitative
- Market size and forecast
- Market segmentation
- Geographical insights
- Competitive landscape
Key Questions Answered
- What are the key global market and the regional market share?
- What are the revenue-generating key market segments?
- What are the key factors driving and challenging this market’s growth?
- Who are the key market vendors and their growth strategies?
- What are the latest trends influencing the growth of this market?
- What are the variables influencing the market growth in the primary regions?
- What are the factors influencing the growth of the parent market?
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