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The Protein engineering market size is forecast to increase by USD 3.60 billion, at a CAGR of 19.03% between 2023 to 2028. The market forecast growth hinges on several key factors, notably the increasing demand for enhanced food and industrial products, driven by evolving consumer preferences for quality and sustainability. Additionally, the rising prevalence of chronic diseases underscores the need for innovative solutions in the healthcare and pharmaceutical industries. Furthermore, the development of new biomanufacturing processes presents opportunities for improved efficiency and product quality across various sectors. These interconnected trends highlight the importance of technological advancements and market innovation in addressing global challenges and driving industry growth. As companies adapt to changing consumer demands and regulatory landscapes, they contribute to the expansion and diversification of markets, fostering economic development and societal well-being.
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The market is witnessing significant growth driven by advancements in biotechnology and pharmaceutical research, with notable contributions from institutions like Eindhoven University of Technology. This market is fueled by the increasing prevalence of chronic diseases, spurring the development of targeted therapies and precision medicine approaches, particularly in cancer treatment. The emergence of AI-designed proteins and bioluminescent testing kits is revolutionizing the field, enabling researchers to generate biomedicines with enhanced efficacy. Monoclonal antibodies, insulin, and other protein-based therapies are gaining traction, offering promising outcomes for patients with cancer and autoimmune diseases. Synthetic biology plays a pivotal role in the production of these protein-based drugs, augmenting the capabilities of biotechnology and pharmaceutical businesses. As the market continues to evolve, stakeholders are closely monitoring buying behavior, patient outcomes, and the adoption of protein engineering solutions in diagnostics and therapeutics. The development of a bioluminescent testing kit holds promise in detecting chronic & lifestyle disorders efficiently, leveraging affinities with specific host strain, offering a comprehensive product & service for advanced bioluminescent testing capabilities.
Demand for improved food and industrial products is the key factor driving the market. In the food industry, consumer preference for healthier and more sustainable food choices has driven demand for new proteins with improved nutritional profiles. Protein engineering allows the development of proteins with optimized amino acid compositions, improved digestibility, and reduced allergenicity.
Furthermore, protein engineering plays a central role in industrial processes. Enzymes, which are specialized proteins, are widely used as biological catalysts in various industrial applications. By designing enzymes with greater activity, stability, and specificity, end-user industries such as biofuels and detergents can realize more efficient production processes that are more environmentally friendly. Additionally, protein engineering techniques are crucial in the development and optimization of interferons, enhancing their therapeutic efficacy and biological activity. These advancements in interferon engineering are anticipated to broaden their applications in treating various diseases, thereby driving growth in the global protein engineering market during the forecast period.
The adoption of generative AI in protein engineering is the key trend shaping the growth of the market. The integration of synthetic AI techniques is revolutionizing the way proteins are engineered, offering unprecedented opportunities to boost research and development in different fields. One of the important drivers for the adoption of generalized AI in protein engineering is its ability to dramatically speed up the protein design and optimization process. In addition, generalized AI makes it possible to explore a wider string space than before.
Furthermore, the integration of computer simulations into the AI platform which are generative allows researchers to predict the behavior of newly engineered proteins. These virtual tests greatly reduce the need for extensive testing in the lab, saving time and resources, and reducing the possibility of trial and error repetition. Hence, these factors are expected to fuel the growth of the global protein engineering market during the forecast period.
Lack of knowledge of protein structure is a challenge that affects the growth of the market. The lack of precise protein structural information limits the ability to predict how protein sequences fold and interact with other molecules. This limitation hinders the rational design of proteins with desired functions, as it becomes difficult to predict how mutations and modifications will affect protein behavior.
Moreover, this challenge is especially pronounced for proteins that are structurally very complex or have no homologous structures in existing databases. These proteins may have unique functions and properties that can be exploited for engineering, but due to the lack of structure-related data, exploiting the unique functions and properties of such proteins through protein engineering seems difficult. Thus, such factors are anticipated to hinder the growth of the global protein engineering market during the forecast period.
The market share growth by the instruments segment will be significant during the forecast period. In the instruments segment, a variety of tools are used. These include high-performance liquid chromatography (HPLC) systems, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, protein crystallization platforms, and automated protein expression systems. These tools facilitate various steps of protein engineering, from initial characterization to structure identification and optimization.
The instruments segment was valued at USD 725.80 million in 2018. The instruments segment facilitates protein engineering by accelerating processes that were previously time- and labor-intensive. The growing demand for biopharmaceuticals, including monoclonal antibodies, enzymes, and therapeutic proteins, has driven the need for advanced tools to facilitate the detection, optimization, and production of these complex molecules. The convergence of various technologies, such as AI, computational biology, and structural analysis, has led to the creation of integrated tools that provide comprehensive solutions to overcome environmental challenges in protein engineering. Thus, such factors will drive the growth of the segment during the forecast period.
North America is estimated to contribute 38% to the growth of the global market during the forecast period.
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The protein engineering market in North America is heavily focused on biopharmaceutical applications. The development of new therapeutic proteins, including monoclonal antibodies, enzymes, and cytokines, is a driving force in North America, supported by the region's expertise in drug discovery and development biology. Furthermore, the North American region is home to many leading pharmaceutical companies, biotech companies, and research institutes that are at the forefront of advances in protein engineering.
Further, North America has always been at the forefront of technological innovation related to protein engineering. North America is at the forefront of advances in computational modeling, structural biology engineering, and AI-based approaches that enable rapid protein design, optimization, and characterization. Collaborations between academia, industry, and research institutions are common in North America. Hence, such factors are expected to drive market growth in this region during the forecast period.
The market is fragmented in nature. Some significant players include
Waters Corp.: The company offers protein engineering solutions for the development and successful commercialization of protein based biopharmaceuticals and diagnostic reagents.
The research report also includes detailed analyses of the competitive landscape of the market and information about 15 market companies, including:
Agilent Technologies Inc., Amgen Inc., Bio Rad Laboratories Inc., Bruker Corp., Danaher Corp., Eli Lilly and Co., General Electric Co., GenScript Biotech Corp., Merck KGaA, New England Biolabs Inc., Novo Nordisk AS, PerkinElmer Inc., Promega Corp., Thermo Fisher Scientific Inc.
The market forecasting report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Million" for the period 2024 to 2028, as well as historical data from 2018 to 2022 for the following segments.
The Market is witnessing remarkable growth driven by advancements in biotechnology and pharmaceutical businesses. With a focus on precision medicine and personalized therapies, protein-based therapies are becoming increasingly vital in treating chronic diseases like cancer, autoimmune diseases, and cardiovascular conditions. Innovations in AI-designed proteins and rational protein design are revolutionizing the field, enabling the generation of biomedicines tailored to individual patient needs. Private and public investments fuel research and development spending, leading to the development of targeted therapies and personalized diagnostics. Key stakeholders, including Ginkgo Bioworks and the Centers for Disease Control and Prevention (CDC), play crucial roles in shaping the market landscape. With a focus on improving patient outcomes and addressing chronic and lifestyle disorders, the Protein Engineering Market continues to thrive, supported by ongoing advancements in synthetic biology and enzyme R&D.
Moreover, the market is experiencing remarkable growth driven by advancements in biomedicines and the increasing prevalence of chronic and lifestyle disorders like diabetes and cardiovascular issues. Bioluminescent diagnostic kits are revolutionizing cancer treatment and diagnosis, particularly in breast cancer detection, aided by the insights provided by Canadian Cancer Statistics. Protein therapeutics, including insulin and erythropoietin, play crucial roles in addressing protein deficiency disorders and immune system modulation. With a focus on R&D spending, companies are developing innovative protein-based vaccines and non-protein drugs, catering to diverse medical needs. Ginkgo Enzyme Services and manufacturing processes are integral to protein type development, ensuring product and service quality. The market's growth is also fueled by investments in cardiovascular repair and addressing coagulation and colony-stimulating factors, showcasing changing buying behaviors towards protein-based treatments.
Additionally, the Market is experiencing significant growth driven by advancements in biomedicines and the increasing prevalence of chronic and lifestyle disorders. Protein engineering techniques enable the development of innovative bioluminescent diagnostic kits and testing kits, catering to diverse healthcare needs. Moreover, the market benefits from the rising demand for coagulation factors and interferons, essential in treating various medical conditions. Conference and webinar materials facilitate knowledge exchange and drive research in protein engineering, supported by funds allocated for biomedicine research. Host strains play a crucial role in biomedicine production, ensuring product and service quality. Protein engineering addresses critical healthcare challenges such as Protein-Energy Malnutrition (PEM), offering promising solutions to improve patient outcomes and combat disease. With the continuous evolution of protein engineering technologies, the market is poised for sustained growth and innovation.
Market Scope |
|
Report Coverage |
Details |
Page number |
177 |
Base year |
2023 |
Historic period |
2018 - 2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 19.03% |
Market Growth 2024-2028 |
USD 3.60 billion |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
15.51 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 38% |
Key countries |
US, UK, Germany, China, and Japan |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
Agilent Technologies Inc., Amgen Inc., Bio Rad Laboratories Inc., Bruker Corp., Danaher Corp., Eli Lilly and Co., General Electric Co., GenScript Biotech Corp., Merck KGaA, New England Biolabs Inc., Novo Nordisk AS, PerkinElmer Inc., Promega Corp., Thermo Fisher Scientific Inc., and Waters Corp. |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for the forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Product
7 Market Segmentation by End-user
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Opportunity/Restraints
11 Competitive Landscape
12 Competitive Analysis
13 Appendix
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