Rickets - A Pipeline Analysis Report
- Published: Jul 2018
- Pages: 46
- SKU: IRTNTR23277
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This pipeline analysis report provides detailed insights into the clinical trials landscape of the drug development for rickets including molecules at pre-clinical and discovery stage. The report also offers comprehensive information about the therapeutic assessment of the pipeline molecules based on various segmentations such as therapy, route of administration, and target.
Overview of the drug development pipeline for rickets
Rickets is a skeletal disorder occurring due to the deficiency of vitamin D, calcium, or phosphate. There are important nutrients for the development of strong and healthy bones. People with rickets generally have weak and soft bones, stunted growth, and skeletal deformities. It is the most common disease in children aged between 6 and 36 months. Children with rickets might not get enough vitamin D if they live in a region with low sunlight, follow a vegetarian diet or do not consume milk products. Vitamin D facilitates the absorption of calcium and phosphate in the small intestine. A vitamin D deficiency makes it difficult for the human body to maintain sufficient levels of calcium and phosphate. During this situation, the body produces hormones that release calcium and phosphate from the bones, which makes them weak and soft. The disease is rare in developed and developing countries due to the introduction of fortified foods such as cereals with added vitamin D. In areas such as Africa, some parts of Asia, and South America, the incidence and prevalence rates of rickets are very high owing to the lack of nutritional food. Furthermore, in most of the industrialized countries, the prevalence of rickets in general population reduced after the introduction of clean-air legislation and dietary supplementation. Consequently, the rising incidences of rickets in the emerging economies is expected to promote the drug development for rickets in the forthcoming years.
According to this pipeline analysis report, almost half of the drug molecules in the pipeline are being developed for autosomal recessive hypophosphatemic rickets type 2 (ARHR2) and rest half for X-linked hypophosphatemia (XLH). Our market research analysts have also identified that most of these molecules are in the pre-clinical development stage and a considerable number of molecules have been discontinued from development.
Companies covered
This pipeline analysis report provides a detailed analysis of the companies that are involved in the development of drug molecules for the treatment of rickets. In addition to providing information on the various stages of molecules developed by companies for different indications, this pipeline analysis report also provides information about the drug molecules discontinued by companies.
Some of the companies covered in this pipeline analysis report are –
- Kyowa Hakko Kirin
- Inozyme Pharma
Therapeutic assessment of the drug development pipeline for rickets by route of administration
- Subcutaneous
The subcutaneous route of administration (ROA) involves the application of the drug directly into the layer of the skin below the dermis and the epidermis, which will have a more direct effect on the target cells.
Therapeutic assessment of the drug development pipeline for rickets by therapy
- Monotherapy
According to this pipeline analysis report, all the molecules that are currently in the drug development pipeline for rickets are being developed as monotherapy drugs and most of these molecules are in the pre-clinical stage of development.
Key questions answered in the report include
- What are the drug molecules in the various development stages for rickets?
- What are the companies that are currently involved in the development of drug molecules for rickets?
- Insight into discontinued/inactive molecules with appropriate reasoning?
- What are the major regulatory authorities approving drugs in various regions?
- Detailed profiling of each active molecule
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PART 01: EXECUTIVE SUMMARY
PART 02: SCOPE OF THE REPORT
PART 03: RESEARCH METHODOLOGY
PART 04: INTRODUCTION
PART 05: MAJOR REGULATORY AUTHORITIES
- US
- Europe
- China
PART 06: PIPELINE LANDSCAPE
PART 07: COMPARATIVE ANALYSIS
- Discovery stage molecules
- Pre-clinical stage molecules
- Inactive and discontinued molecules
PART 08: INDICATION ANALYSIS
PART 09: THERAPEUTIC ASSESSMENT (THERAPY BASED)
PART 10: THERAPEUTIC ASSESSMENT (ROA BASED)
PART 11: THERAPEUTIC ASSESSMENT BY TARGET
PART 12: KEY COMPANIES
- Active companies: Category and parameters
PART 13: APPENDIX
- List of abbreviations
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
- Manufacturers and suppliers
- Channel partners
- Industry experts
- Strategic decision makers
Secondary sources
- Industry journals and periodicals
- Government data
- Financial reports of key industry players
- Historical data
- Press releases

DATA ANALYSIS
Data Synthesis
- Collation of data
- Estimation of key figures
- Analysis of derived insights
Data Validation
- Triangulation with data models
- Reference against proprietary databases
- Corroboration with industry experts

REPORT WRITING
Qualitative
- Market drivers
- Market challenges
- Market trends
- Five forces analysis
Quantitative
- Market size and forecast
- Market segmentation
- Geographical insights
- Competitive landscape
Key Questions Answered
- What are the key global market and the regional market share?
- What are the revenue-generating key market segments?
- What are the key factors driving and challenging this market’s growth?
- Who are the key market vendors and their growth strategies?
- What are the latest trends influencing the growth of this market?
- What are the variables influencing the market growth in the primary regions?
- What are the factors influencing the growth of the parent market?
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