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The global hematopoietic stem cells transplantation (HSCT) market size is estimated to grow by USD 2,383.61 million between 2022 and 2027 and the size of the market is expected to accelerate at a CAGR of 6.5%. Factors influencing market growth include the advancement of technology, rising demand for customized medicine, and decreased morbidity and mortality rates. The improved treatment options, HLA typing, and supportive care given to patients prior to or after the transplant help them fight infectious diseases and that is why hematopoietic stem cell transplantation has become a preferable option. Owing to the increasing emergence of regenerative therapies across the world, this market will significantly grow during the forecast period. It is an oligopoly market that is mainly dominated by key vendors such as AllCells, Lonza, Merck, and Sanofi, followed by other prominent vendors such as STEMCELL Technologies and Mesoblast. The market is witnessing strong research and development in the field of stem cells, which is expected to help some new vendors to enter the market.
Technavio has segmented the market on the basis of Application, Type, and Geography. The application segment is divided into bone marrow transplant, peripheral blood stem cell transplant, and cord blood transplant, the type segment is fragmented into autologous HSCT and allogeneic HSCT followed by geography which includes key regions such as North America, Europe, Asia, and Rest of World. It also includes an in-depth analysis of drivers, trends, and challenges. Furthermore, the report includes historic market data from 2017 to 2021.
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Based on application analysis, the market is classified into bone marrow transplant, peripheral blood stem cell transplant, and cord blood transplant. The sub-segment bone marrow transplant is leading the market growth. The bone marrow transplant segment was valued at USD 2,614.69 million in 2017 and continues to grow during the forecast period.
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A bone marrow transplant is a treatment that replaces bone marrow that is not producing enough healthy blood cells or is dysfunctional with healthy blood-forming stem cells. Doctors and medical practitioners recommend bone marrow transplants to patients suffering from several malignant and noncancerous disorders, including acute leukemia, adrenoleukodystrophy, chronic leukemia, aplastic anemia, bone marrow failure syndromes, and others. Bone marrow transplant also improves the prospects of cure and survival for patients with such disorders, resulting in a rising demand for bone marrow transplants among patients. This, in turn, will fuel the global hematopoietic stem cell transplantation (HSCT) market's growth throughout the forecast period.
The type segment is divided into two parts that are autologous HSCT and allogeneic HSCT. The major advantage of an autologous transplant is the body recognizes its cells, and hence, does not reject the transplant. This also indicates lesser chances of GvHD. The autologous HSCT segment of the global hematopoietic stem cells transplantation (HSCT) market currently dominates the global hematopoietic stem cells transplantation (HSCT) market, with the highest market share of 59.00% in 2021. Moreover, autologous transplant involves cryopreservation of the stem cells, which allows the administration of high doses of chemotherapy and radiotherapy to be risk-free. Further, an autologous transplant ensures rapid immune recovery of the patients, which would ultimately drive market growth during the forecast period.
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North America is estimated to contribute 40% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
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In 2022, the US was the largest revenue contributor to the HSCT market in the region, attributed to the increasing awareness about stem cell therapy in the country and the availability of advanced healthcare infrastructure. This ensures the continuous delivery of therapies to patients undergoing treatment. Hence, the market in the US is expected to grow steadily during the forecast period.
Unlike the traditional therapeutic market, there are a number of policies and regulation-related considerations pertaining to the use of stem cell therapies. However, despite stringent regulations laid by regulatory authorities in the region, many factors, such as the high prevalence of bone marrow diseases and several types of blood carcinomas, are propelling the market growth in North America. Furthermore, healthcare is financed through a mix of financing arrangements, including government spending and compulsory health insurance, as well as voluntary health insurance and private funds such as households' out-of-pocket payments, NGOs, and private corporations (together termed as voluntary). All these factors are expected to drive the growth of the market in the US and, subsequently, in North America.
The regional market was greatly impacted by the COVID-19 outbreak in 2020, but with the implementation of widespread vaccination campaigns and the resumption of healthcare operations in 2021, healthcare facilities have seen an increase in the number of leukemia patients seeking treatment. As a result, there is a growing demand for effective therapeutics from healthcare facilities, which is expected to drive the demand for HSC transplantations in the North American region during the forecast period, ultimately leading to significant market growth.
There is high competition in the hematopoietic stem cells transplantation (HSCT) Market. Among several market players, the organization AllCells Corp stands out among the competitors due to technological innovation and the on-point marketing strategy.
AllCells Corp- To make an impact in the hematopoietic stem cells industry, the company provides a wide range of human hematopoietic cells and molecular products such as whole blood, leukoplakia, mobilized leukoplakia, bone marrow, and cord blood.
The report also includes detailed analyses of the competitive landscape of the market and information about 15 market vendors, including:
Technavio’s report consists of a holistic analysis of the key development analysis, development stage, pipeline analysis, FDA approval, market players, their marketing strategies, and powerful innovations to help any client gain a competitive edge.
There are multiple factors influencing market growth. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges.
Key Hematopoietic Stem Cells Transplantation (HSCT) Market Driver
Recent years have witnessed a rise in the adoption of hematopoietic stem cells transplantation (HSCT) due to the development of safer procedures and improved success rates resulting from technological advancements. This trend is expected to continue during the forecast period, with the global HSCT market being driven by advancements in technology, particularly the development of better and more sophisticated instruments. For example, Ranfac has introduced its patented technology, Marrow Cellution, to address the challenges associated with conventional transplant syringes. The use of traditional needles has often led to contamination of peripheral blood, resulting in poor cellular yield. This has necessitated the adoption of measures to meet the desired cellular demands for treating various diseases. Therefore, the Marrow Cellution technology, which enables high-quality stem and progenitor cells to be harvested within a narrow space with limited peripheral blood contamination, is expected to fuel the market growth during the forecast period
Significant Hematopoietic Stem Cells Transplantation (HSCT) Market Trend
Growing demand for personalized medicine is a notable trend in the market. The concept of personalized medicine involves tailoring treatments to the specific needs, characteristics, and preferences of individual patients. To this end, research organizations are exploring various ways to develop personalized treatments using mesenchymal stem cells due to their numerous benefits. These benefits include a lower risk of immune rejection, no need for embryonic stem cells, reduced dependence on anti-rejection drugs, lower risk of graft rejection, and a decreased chance of developing GvHD.
While immunosuppressive therapy is the mainstay of treatment for hematological malignancies and solid tumors, its side effects often outweigh its therapeutic benefits. Mesenchymal stem cells (MSC), which are located in the vascular region of the bone marrow, provide cellular support to the HSC niche and possess immunosuppressive properties that are beneficial for HSCT and the treatment of inflammatory and autoimmune diseases. As a result, the use of MSC during HSCT has led to improved engraftment rates of hematopoietic stem cells by reducing the incidence of GvHD, which is expected to contribute to market growth during the forecast period.
Major Hematopoietic Stem Cells Transplantation (HSCT) Market Challenge
Increased risk of complications post-HSCT is a major challenge in the market. The field of transplant technology and supportive care practices has seen significant advancements, resulting in improved survival rates among patients following transplantation. However, despite these developments, individuals who have undergone hematopoietic stem cell transplantation (HSCT) remain at risk of developing long-term complications, including endocrinopathy, cardiopulmonary issues, musculoskeletal disorders, and subsequent malignancies. These complications have a direct impact on the mortality and morbidity rates of HSCT patients. As a result, the increased morbidity experienced by HSCT patients has led to a growing demand for alternative treatment regimens, which is hindering the market growth.
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Key Hematopoietic Stem Cells Transplantation (HSCT) Market Customer Landscape
The report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.
Global Hematopoietic Stem Cells Transplantation (HSCT) Market Customer Landscape
The report forecasts market growth by revenue at global, regional & country levels and provides an analysis of the latest trends and growth opportunities from 2017 to 2027.
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Hematopoietic Stem Cells Transplantation (HSCT) Market Scope |
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Report Coverage |
Details |
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Page number |
159 |
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Base year |
2022 |
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Historic period |
2017-2021 |
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Forecast period |
2023-2027 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 6.5% |
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Market growth 2023-2027 |
USD 2,383.61 million |
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Market structure |
Fragmented |
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YoY growth 2022-2023(%) |
5.89 |
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Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
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Performing market contribution |
North America at 40% |
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Key countries |
US, Canada, UK, Germany, and China |
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Competitive landscape |
Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks |
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Key companies profiled |
Athersys Inc., Beike Biotechnology Co. Ltd., bluebird bio Inc., Cellular Biomedicine Group Inc., FUJIFILM Corp., Gamida Cell Ltd., Lineage Cell Therapeutics Inc., Lonza Group Ltd., MEDIPOST Co. Ltd., Merck and Co. Inc., Mesoblast Ltd., Pluristem Therapeutics Inc., Sanofi SA, Sartorius CellGenix GmbH, Taiga Biotechnologies Inc., Takeda Pharmaceutical Co. Ltd., Talaris Therapeutics Inc., ThermoGenesis Holdings Inc., and AllCells Corp. |
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Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period |
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Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Application
7 Market Segmentation by Type
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
Secondary sources
DATA ANALYSIS
Data Synthesis
Data Validation
REPORT WRITING
Qualitative
Quantitative
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