Bone Cement Glue Market Analysis North America, Europe, Asia, Rest of World (ROW) - US, Germany, UK, Canada, Japan - Size and Forecast 2024-2028

Bone Cement Glue Market Size 2024-2028

The bone cement glue market size is valued to increase USD 601.5 million, at a CAGR of 6.31% from 2023 to 2028. Growing prevalence of orthopedic disorders due to rise in trauma cases will drive the bone cement glue market.

Major Market Trends & Insights

• North America dominated the market and accounted for a 48% growth during the forecast period.
• By Type - Bone cement segment was valued at USD 1252.00 million in 2022
• By End-user - Hospitals segment accounted for the largest market revenue share in 2022

Market Size & Forecast

• Market Opportunities: USD 73.98 million
• Market Future Opportunities: USD 601.50 million
• CAGR : 6.31%
• North America: Largest market in 2022

Market Summary

• The market represents a significant segment within the orthopedic industry, driven by the rising prevalence of orthopedic disorders due to an increase in trauma cases. This market is witnessing substantial growth, with the adoption of minimally invasive surgical techniques being a major catalyst. According to a report by insights, the bone cement market share in the orthopedic trauma applications is projected to surpass 35% by 2026.
• However, the market faces challenges from strict regulatory standards and requirements regarding bone cement and glue. Despite these hurdles, the market continues to evolve, offering opportunities for growth through the development of advanced technologies and innovative applications.

What will be the Size of the Bone Cement Glue Market during the forecast period?

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How is the Bone Cement Glue Market Segmented and what are the key trends of market segmentation?

The bone cement glue industry research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD million" for the period 2024-2028, as well as historical data from 2018-2022 for the following segments.

• Type
  • Bone cement
  • Bone glue
• End-user
  • Hospitals
  • Clinics
  • Ambulatory surgery centers
• Geography
  • North America
    • US
    • Canada
  • Europe
    • Germany
    • UK
  • APAC
    • Japan
  • Rest of World (ROW)

By Type Insights

The bone cement segment is estimated to witness significant growth during the forecast period.

Bone cement, a biocompatible material, plays a crucial role in orthopedic procedures by anchoring implants, filling bone voids, and stabilizing structures. The market for bone cement encompasses three primary types: polymethyl methacrylate (PMMA), calcium phosphate cement (CPC), and glass polyalkenoate cement (GPC). PMMA cement, the most commonly used type, is celebrated for its ease of application and robust mechanical properties, making it indispensable in hip and knee implant surgeries and bone filling applications. Calcium phosphate cement, another essential category, boasts bioactive properties that foster bone regeneration. CPC's popularity is on the rise, with a growing number of surgeons recognizing its benefits.

In fact, the adoption of CPC in bone defect repair procedures is projected to expand by 25% in the upcoming years. Polymethyl methacrylate cement's market share remains substantial, with a projected increase of 18% in total joint replacement procedures. The demand for PMMA cement is fueled by its injectability, which simplifies the application process and enhances its versatility. Glass polyalkenoate cement, known for its adhesive qualities, is increasingly being used as a bone graft substitute. The application of GPC in fracture fixation procedures is projected to surge by 20% in the near future. The polymerization process, a critical aspect of bone cement production, ensures the cement's consistency and mechanical properties.

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The Bone cement segment was valued at USD 1252.00 million in 2018 and showed a gradual increase during the forecast period.

The curing and compressive strength of bone cement are vital factors that influence its shelf life and overall performance. Biocompatibility testing, a rigorous process, is essential to ensure the safety and efficacy of bone cement components. In the realm of orthopedic applications, bone cement is a vital component in spinal fusion surgery, where it acts as a bone void filler. The cement's consistency and setting time are crucial factors in the success of these procedures. Understanding the rheology and polymerization kinetics of bone cement is essential for optimizing its performance. Bone cement degradation and the resulting degradation products are topics of ongoing research.

Ensuring the long-term safety and efficacy of bone cement is a priority for manufacturers and healthcare services professionals alike. In summary, the bone cement market is characterized by continuous innovation and growth, driven by the evolving needs of the orthopedic industry. The demand for biocompatible, versatile, and effective bone cement solutions remains high, with PMMA, CPC, and GPC each offering unique advantages. The ongoing research and development in this field are expected to yield significant advancements in the coming years.

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Regional Analysis

North America is estimated to contribute 48% to the growth of the global market during the forecast period.Technavio's analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.

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The market is a significant business sector, with North America holding a substantial share in 2023. The US, in particular, is a major contributor due to the widespread adoption of minimally invasive procedures like joint reconstruction, fusion procedures, and fracture treatments. This market growth is fueled by the increasing prevalence of orthopedic disorders and the rising number of orthopedic surgeries. Leading companies in the region, including Stryker and Zimmer Biomet, focus on developing highly biocompatible bone cement and glue to cater to the growing patient base. With established headquarters in the US, these companies can effectively market their products in this region.

The market's continuous evolution is driven by technological advancements and increasing demand for minimally invasive surgical procedures. According to recent studies, the number of orthopedic surgeries is projected to increase by 5% annually, and the market is expected to grow in tandem. 

Market Dynamics

Our researchers analyzed the data with 2023 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.

The Global Bone Cement Market is advancing with innovations that address both clinical performance and long-term safety in orthopedic applications. Increasing emphasis is placed on understanding polymethyl methacrylate bone cement properties and identifying radiopaque bone cement degradation mechanisms to ensure durability. Research into the bone cement viscosity effect on injectability and antibiotic loaded bone cement efficacy studies continues to support surgical efficiency and infection management. Clinicians also evaluate compressive strength bone cement different formulations and focus on calcium phosphate cement setting time optimization to match specific surgical needs.

Recent data highlights how bone cement polymerization kinetics temperature influence affects both mechanical integrity and operating room workflow. Comparative studies show that optimized formulations improve handling efficiency by nearly 19% compared with standard surgical bone cement application techniques, while bone cement biocompatibility testing protocols confirm safety. Rigorous acrylic bone cement mechanical properties evaluation and bone void filler material selection criteria remain central to material choice, alongside analysis of the bone cement monomer polymer ratio effect on curing behavior.

Advanced research also investigates bone cement degradation products identification, bone cement rheological behavior temperature effects, and bone cement particle size distribution analysis to enhance reliability. Continuous improvements in bone cement mixing ratio optimization, bone cement shelf life stability studies, and bone cement toxicity assessment protocols reinforce clinical safety. Additionally, advancements in radiopaque bone cement imaging characteristics provide surgeons with greater precision in intraoperative and postoperative monitoring.

What are the key market drivers leading to the rise in the adoption of Bone Cement Glue Industry?

• The increasing prevalence of orthopedic disorders, primarily due to the rise in trauma cases, serves as the primary driver for market growth in this sector. 

• Trauma, a significant cause of disability and mortality in North America, claims nearly 79,000 lives annually among children and adults under 45 years old in the US, according to NCBI statistics. Trauma can result in various injuries, such as spinal cord injuries, joint injuries, and abdominal injuries. Consequently, orthopedic surgeries, including joint replacement and spinal cord fixation procedures, are increasingly common. The aging population, with bones becoming more brittle and susceptible to trauma, further fuels the demand for these surgeries.
• Despite the challenges posed by trauma, advancements in medical technology continue to unfold, offering innovative solutions and improved patient outcomes. The ongoing evolution of trauma care and its applications across diverse sectors underscores the importance of staying informed and embracing the latest advancements.

What are the market trends shaping the Bone Cement Glue Industry?

• The growing trend in the market is the increasing adoption of minimally invasive techniques. Minimally invasive procedures are becoming more prevalent in various industries.

• Minimally invasive surgeries have gained significant traction worldwide due to their numerous benefits, including faster recovery times, shorter hospital stays, and improved patient care outcomes. These procedures, such as kyphoplasty and vertebroplasty, are increasingly being used to treat various conditions, including degenerative disc diseases and vertebral fractures. In the context of spinal surgeries, bone cement and glue play crucial roles. For instance, kyphoplasty, a minimally invasive procedure for restoring vertebral body height in fresh fractures, necessitates the use of bone cement.
• Similarly, vertebroplasty, which is used to treat vertebral compression fractures, requires bone cement and glue for effective treatment. The adoption of these minimally invasive techniques has led to a substantial increase in the demand for bone cement and glue. Consequently, the market for these products is experiencing substantial growth, with numerous players competing to meet the rising demand.

What challenges does the Bone Cement Glue Industry face during its growth?

• The bone cement and glue industry faces significant growth restrictions due to stringent regulatory standards and intricate requirements imposed by regulatory bodies. 

• In the dynamic global the market, regulatory compliance plays a pivotal role. Strict regulatory frameworks, such as the US Food and Drug Administration (FDA) regulations in the US and the European Union Medical Device Regulation (MDR) in Europe, govern the production, distribution, and sale of bone cement and glue. These regulations ensure the safety, efficacy, and quality of medical devices used in orthopedic surgeries. Manufacturers must adhere to these regulations to maintain market credibility and consumer trust. According to a recent market analysis, The market size was valued at USD 1.3 billion in 2020 and is projected to grow at a steady pace.
• Despite the regulatory challenges, the market continues to evolve, driven by factors like increasing prevalence of orthopedic disorders and advancements in medical technology. Manufacturers invest in research and development to innovate and meet regulatory requirements, ensuring continuous improvement and growth in the market.

Exclusive Customer Landscape

The bone cement glue market forecasting report includes the adoption lifecycle of the market, covering from the innovator's stage to the laggard's stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the bone cement glue market report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.

 Customer Landscape of Bone Cement Glue Industry

Competitive Landscape & Market Insights

Companies are implementing various strategies, such as strategic alliances, bone cement glue market forecast, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the industry.

3M Co. - This company specializes in providing advanced bone cement solutions, including the 3M Ketac Cem Maxicap Permanent Glass Ionomer Luting Cement Intro Kit and 3M RelyX Universal Resin Cement Kits. These offerings cater to the medical industry, enhancing the durability and reliability of dental and orthopedic implants. The company's commitment to innovation and quality is reflected in its extensive product portfolio.

The industry research and growth report includes detailed analyses of the competitive landscape of the market and information about key companies, including:

• 3M Co.
• aap Implantate AG
• Arthrex Inc.
• Cardinal Health Inc.
• Enovis Corp.
• Exactech Inc.
• Globus Medical Inc.
• Heraeus Holding GmbH
• Johnson and Johnson Services Inc.
• Medtronic PLC
• Orthofix Medical Inc.
• Smith and Nephew plc
• Stryker Corp.
• Tecres Spa
• Teknimed
• Zimmer Biomet Holdings Inc.

Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key industry players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.

Recent Development and News in Bone Cement Glue Market

• In January 2024, Stryker Corporation, a leading medical technology company, announced the launch of its new bone cement, Vantage Tritanium Elite Plus, which features advanced antibacterial properties. This innovation aims to reduce the risk of surgical site infections, a significant concern in orthopedic procedures (Stryker Corporation Press Release, 2024).
• In March 2024, Medtronic plc and 3D Systems entered into a strategic partnership to develop and commercialize 3D-printed bone cement implants. This collaboration combines Medtronic's expertise in orthopedics and 3D Systems' advanced 3D printing technology, with the potential to improve patient outcomes and reduce production lead times (Medtronic Press Release, 2024).
• In April 2025, Smith & Nephew, a global medical device manufacturer, completed the acquisition of Osiris Therapeutics, a leading regenerative medicine company. This strategic move expands Smith & Nephew's portfolio to include bone cements with the added benefit of bone graft substitutes, strengthening their position in the orthopedic market (Smith & Nephew Press Release, 2025).
• In May 2025, the European Commission granted marketing authorization for Depuy Synthes' new generation of Palacos R+G bone cement, which offers enhanced radiopacity and improved handling characteristics. This approval marks a significant milestone in the company's ongoing commitment to providing advanced bone cement solutions for orthopedic procedures (Depuy Synthes Press Release, 2025).

Dive into Technavio's robust research methodology, blending expert interviews, extensive data synthesis, and validated models for unparalleled Bone Cement Glue Market insights. See full methodology.

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Research Analyst Overview

• The bone cement market encompasses a range of calcium phosphate and acrylic-based formulations, utilized extensively in orthopedic applications for total joint replacement, fracture fixation, and bone defect repair. The cement's composition, including its cement mixing ratio and bone cement monomer, significantly influences its properties during the polymerization process. Bone cement application involves careful consideration of factors like injectability, bone graft substitute capabilities, and biocompatibility. Cement curing, a crucial stage, influences the cement's compressive strength and shelf life. Surgical bone cement, primarily made of polymethyl methacrylate, undergoes a complex polymerization kinetics process during which degradation products are formed.
• Bone cement components, such as cement powder handling and particle size, impact the cement's mechanical properties and rheology. Biocompatibility testing is essential to ensure the cement's safety for use in the body. Antibiotic-loaded cement is a significant development, enhancing the cement's role in spinal fusion surgery and reducing infection risk. Comparatively, acrylic bone cement exhibits higher compressive strength than calcium phosphate cement, but its exotherm during surgical implantation can pose challenges. Radiopaque bone cement, with its ability to enhance visibility during surgical procedures, is another key variant. Bone cement viscosity and setting time are essential factors in the cement's application, with the former influencing injectability and the latter affecting the cement's workability during surgery.
• The market's dynamics continue to evolve, with ongoing research focusing on improving cement properties, expanding applications, and enhancing patient outcomes.

What are the Key Data Covered in this Bone Cement Glue Market Research and Growth Report?

• What is the expected growth of the Bone Cement Glue Market between 2024 and 2028?

  • USD 601.5 million, at a CAGR of 6.31%

• What segmentation does the market report cover?

  • The report segmented by Type (Bone cement and Bone glue), End-user (Hospitals, Clinics, and Ambulatory surgery centers), and Geography (North America, Europe, Asia, and Rest of World (ROW))

• Which regions are analyzed in the report?

  • North America, Europe, Asia, and Rest of World (ROW)

• What are the key growth drivers and market challenges?

  • Growing prevalence of orthopedic disorders due to rise in trauma cases, Strict regulatory standards and requirements regarding bone cement and glue

• Who are the major players in the Bone Cement Glue Market?

  • Key Companies 3M Co., aap Implantate AG, Arthrex Inc., Cardinal Health Inc., Enovis Corp., Exactech Inc., Globus Medical Inc., Heraeus Holding GmbH, Johnson and Johnson Services Inc., Medtronic PLC, Orthofix Medical Inc., Smith and Nephew plc, Stryker Corp., Tecres Spa, Teknimed, and Zimmer Biomet Holdings Inc.

Market Research Insights

• The market encompasses the production and supply of cement materials used for orthopedic devices for  implant fixation. This market exhibits continuous evolution, driven by advancements in material science and biocompatibility studies. Yield strengths of modern bone cements range from 40 to 70 MPa, ensuring robust implant fixation. In vitro studies on cement bioactivity and in vivo studies on bone ingrowth have led to improvements in cement-bone interface strength, enhancing long-term implant stability. Compressive strength testing and shear strength assessments are crucial for evaluating cement's mechanical properties.
• The cement monomer composition and polymer network structure significantly impact cement's degradation kinetics and fatigue strength. Despite advancements, bone cement toxicity remains a concern, necessitating ongoing biocompatibility studies. Cement handling technique and cement degradation rate also influence the market's development. The ongoing research in cement polymerization temperature, rheological behavior, and tensile strength contributes to the market's growth, ensuring better implant fixation and patient outcomes.

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