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The Bioreactors Market size is estimated to grow by USD 2.23 billion at a CAGR of 6.99% between 2023 and 2028. Several companies in the market are offering accessory products with improved features and specific manufacturing standards to make a mark in the market. In addition, these accessories enable market players to retain their existing consumers and also attract new customers. For example, Infors offers a range of accessories for bioreactors, including LabCIP, Exit Gas Analysis, Spin Filter, and Super Safe Sampler. Moreover, these accessories offer additional benefits to bioreactors and aid in bioreactor maintenance. Therefore, such product offerings help attract prospective consumers, thus leading to increased sales and high-volume production among companies which is positively impacting the market.
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The biopharmaceutical companies segment is estimated to witness significant growth during the forecast period. The increasing prevalence of chronic diseases across the globe is resulting in an increasing need for pharmaceutical and biotechnology companies to manufacture high-quality and regulatorily compliant drugs and therapeutic treatments. In addition, during the drug discovery process, the screening and development of clinically relevant compounds are performed using bioreactors.
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The biopharmaceutical companies segment was the largest segment and was valued at USD 1.90 billion in 2018. Moreover, they are used during the preparation of media and buffers, in crossflow filtration, viral clearance, cell harvesting, and virus inactivation. In addition, the cell cultivation takes place in a bioreactor under controlled conditions, which allows the checking of the composition of the nutrient medium, saturation of dissolved oxygen, pH, mixing efficiency, and the temperature of the cell culture media. Furthermore, during the filtration process, which is a valuable step in biomanufacturing of monoclonal antibodies, vaccines, and therapeutic proteins, the bioreactor facilitates the removal of particles and performs sterile filtration using sterilizing-grade filters during the final filling, thereby reducing the bioburden. Hence, such factors are fuelling the growth of this segment which in turn drives the market growth during the forecast period.
Automated segment can be referred to as specialized equipment used for the cultivation of microorganisms, mammalian cells, and other biological entities. In addition, the increasing demand for automated bioreactors is driven by several factors, primarily in the fields of biotechnology, pharmaceuticals, and industrial microbiology. Moreover, the biopharmaceutical industry relies heavily for the production of therapeutic proteins, monoclonal antibodies, vaccines, and other biologics. In addition, automated bioreactors can ensure consistent and controlled production processes, leading to higher product yields and improved product quality. Hence, such are fuelling the growth of this segment which in turn drives the market growth during the forecast period.
There is an increasing use of manual bioreactors in educational institutions to teach students about bioprocess engineering and biotechnology. In addition, they offer a hands-on approach that helps students understand the fundamental principles of bioreactor operation. Moreover, there is an increasing preference for this segment in academic and research settings, where a high level of flexibility and adaptability is required. In addition, the researchers often work with various cell lines, conditions, and experimental setups, and manually operated bioreactors provide greater control over the process. Hence, such are fuelling the growth of this segment which in turn drives the market growth during the market forecasting period.
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Europe is estimated to contribute 29% to the growth of the global market during the market forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that will shape the market during the forecast period.
Another region offering significant growth opportunities to companies is North America. One of the main factors that is significantly contributing to the growth of the market in North America is the high investments in healthcare research and testing in the US. In addition, the strong distribution networks in countries such as the US and Canada, as well as the increasing focus of biopharmaceutical companies on drug discovery and development, are fuelling the growth of the market in North America.
Moreover, the US is the leading contributor in the region due to the presence of a large number of companies, including Danaher, Thermo Fisher Scientific, Merck KGaA, and GE Healthcare. Therefore, the presence of such key companies aids in the efficient management of the supply chain, leading to the timely availability among the end-users in the market and consequently increasing the adoption rates for bioreactors. Hence, such factors are driving the market growth in North America during the forecast period.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about 20 market companies, including:
Automated Engineering Services Inc: The company offers bioreactors such as 3D Perfusion Bioreactor which consists of multiple independent, autoclavable polycarbonate chambers.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The market is witnessing significant growth due to the increasing demand for biologics in the pharmaceutical industry. Bioreactors are essential bioprocessing equipment used to culture cells or microorganisms under ideal conditions for the production of therapeutic proteins, vaccines, and other biological interventions. Stainless steel is a popular material due to its biocompatibility and durability. Hybrid technologies are increasingly being adopted in bioreactors to enhance productivity and reduce production costs. Control types include manual, semi-automatic, and fully automated. The volume ranges from small-scale lab units to large-scale commercial units. Regulatory concerns regarding leachable and extractable substances from bioreactor materials are a significant challenge. Biopharmaceutical companies are focusing on developing bioreactors with improved safety profiles and therapeutic efficacy for various disease indications, including chronic diseases such as diabetes, cancer, and cardiovascular diseases. Bioreactors are used in clinical trials to produce therapeutic proteins and vaccines for personalized medicines. Temperature, pH, and dissolved oxygen are critical parameters that need to be closely monitored during bioprocessing to ensure ideal conditions for cell growth. Yeast is a common microorganism used for the production of industrial enzymes and biofuels. In summary, the market is expected to grow significantly due to the increasing demand for biologics in the pharmaceutical industry and the development of advanced technologies to improve productivity and reduce production costs. However, regulatory concerns and the need for improved safety profiles remain key challenges. There are multiple factors influencing market growth. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges.
One of the key factors driving the market growth is the increased collaborations among stakeholders. There has been an increase in collaborations related to the global market across the world, which has significantly influenced the demand for products and services in different regions. In addition, most of the collaboration initiatives undertaken by bioreactor manufacturers worldwide aim to leverage each other's USP.
Moreover, many of these partnerships with companies have resulted in establishing a strong customer base, technology, financial capability, and R&D capabilities with the aim of increasing their market share and becoming leading players in the global market. Hence, such factors are positively impacting the market. Therefore, it is expected to drive the market growth during the market growth and forecasting period.
A key factor shaping the market growth is the availability of value-added software services. Several companies in the market are striving hard to garner larger market shares by offering additional software and hardware products to end-users. For example, SOLARIS BIOTECHNOLOGY offers Leonardo data viewer, which is software for analyzing and optimizing media and parameters for cultivation as well as for design planning and performing trial runs.
Moreover, it is used along to develop data and monitor the cultivation process. In addition, this interface allows the user to select the software functions intuitively included in the fermenter supply and can be installed on an unlimited number of the end users personal computers. Furthermore, it can used for 24 independent cultivations and can be carried out simultaneously in a bioreactor. Hence, such factors are driving the market growth during the market research and growth period.
Ethical issues related to the bioprocessing of stem cells for regenerative medicine are one of the key challenges hindering the market growth. The main objective of regenerative medicine is restoring the structure and function of damaged organs and tissues using stem cells. In addition, there has been continuous debate over the ethical issues related to regenerative medicine.
For example, the use of human embryonic stem cells in research has always made decision-makers and the scientific fraternity concerned about the ethical issues involved. In addition, some of the important issues include the cloning of embryonic stem cells and the destruction of embryos to create cell lines. Furthermore, the safety, scientific purity, and securing consent for the use of human embryonic stem cell lines for research purposes are becoming major concerns in this field of research. Hence, such concerns are negatively impacting the market. Therefore, it is expected to hinder the market during the market growth analysis period.
The market report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.
Global Market Customer Landscape
The market research report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Billion" for the period 2024 to 2028, as well as historical data from 2018 to 2022 for the following segments.
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Bioreactors are essential equipment used in biopharmaceutical manufacturing for producing recombinant proteins, vaccines, fusion proteins, antibodies, enzymes, 3D tissue, and other biological interventions. The market is growing significantly due to the increasing demand for biologics in disease indications and clinical trials. They come in various types, including hybrid technologies, and materials such as stainless steel. Control types include manual, semi-automated, and fully automated, with automation complexity increasing to ensure ideal conditions for bioprocessing. Their volume ranges from small-scale SUBs to large-scale biomanufacturing facilities. Biopharmaceutical manufacturers and system integrators are key players in the market. The market faces regulatory concerns regarding leachable and extractable materials, valve control, temperature monitoring, surface cleaning, and mass flow controllers. Skilled labor is also essential for operating and maintaining these complex systems. Their critical bioprocess parameters include temperature, pH, dissolved oxygen, and fluid delivery. Steady cell growth and maintaining therapeutic efficacy and safety profiles are crucial for successful bioprocessing. They are used in various industries, including biopharmaceuticals, and are integral to the production of biologics, which have revolutionized disease treatment and diagnosis.
Market Scope |
|
Report Coverage |
Details |
Page number |
161 |
Base year |
2023 |
Historic period |
2018-2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 6.99% |
Market Growth 2024-2028 |
USD 2.23 billion |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
6.1 |
Regional analysis |
North America, Europe, Asia, and the Rest of the World (ROW) |
Performing market contribution |
Europe at 29% |
Key countries |
US, Canada, Germany, China, and India |
Competitive landscape |
Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks |
Key companies profiled |
Automated Engineering Services Inc., Bioengineering AG, BPC Instruments AB, Cell Culture Co. LLC, Danaher Corp., Distek Inc., Donaldson Co. Inc., Eppendorf SE, Getinge AB, Infors AG, LAMBDA CZ sro, Merck KGaA, PBS Biotech Inc., Pierre Guerin SA, Sartorius AG, Solida Biotech GmBH, Thermo Fisher Scientific Inc., Zellwerk GmbH, ZETA, and 3D Biotek LLC |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by End-user
7 Market Segmentation by Type
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
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