Nontuberculous Mycobacterial Infections Market Size 2024-2028
The nontuberculous mycobacterial infections market size is forecast to increase by USD 4.33 billion, at a CAGR of 5.66% between 2023 and 2028.
- The Nontuberculous Mycobacterial (NTM) Infections market is experiencing significant growth due to the increasing prevalence of these infections worldwide. NTM infections, while not as common as tuberculosis, pose a considerable health challenge, particularly in susceptible populations. The growing recognition of NTM and the expanding diagnostic capabilities have led to a rise in detection rates. Despite this growth, the market faces challenges. Limited treatment options for NTM infections remain a major obstacle. Current treatments often involve prolonged courses of antibiotics, which can lead to adverse side effects and treatment resistance. Moreover, the complex nature of NTM infections necessitates a personalized approach to treatment, further complicating matters.
- The adoption of Precision Medicine, which tailors treatment to individual patients based on their genetic makeup and disease characteristics, offers a promising solution. This approach can help improve treatment outcomes while reducing the risk of adverse effects and resistance. Companies seeking to capitalize on this opportunity must invest in research and development to create effective, targeted therapies. Navigating the challenges of limited treatment options and the complexities of NTM infections will require strategic planning and innovative solutions.
What will be the Size of the Nontuberculous Mycobacterial Infections Market during the forecast period?
Explore in-depth regional segment analysis with market size data - historical 2018-2022 and forecasts 2024-2028 - in the full report.
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Nontuberculous mycobacterial (NTM) infections continue to pose a significant challenge in the healthcare industry due to their diverse clinical presentations and increasing incidence. These infections, which can manifest in various forms such as in water, extrapulmonary, disseminated, mycobacterium kansasii, and others, are characterized by their ability to thrive in various environments and affect multiple organ systems. Mycobacterium kansasii, for instance, is a common cause of pulmonary NTM infections, while Mycobacterium avium complex is often associated with disseminated infections. NTM infections have been reported in various sectors, including travelers, HIV patients, infants, and the elderly, among others.
The ongoing research in NTM infection management, diagnosis, and prevention is crucial in addressing the evolving patterns of these infections. For instance, advancements in NTM infection diagnosis have led to the development of more accurate and rapid diagnostic tools, while research into NTM infection microbiology and pathogenesis continues to provide insights into the underlying mechanisms of these infections. NTM infections can also occur in various body sites, including the urine, blood, joint, ear, and tissue, among others. Furthermore, NTM infections have been linked to various environmental sources, such as water, soil, and bioaerosols, highlighting the importance of infection control and prevention measures.
The dynamic nature of NTM infections necessitates continuous monitoring and surveillance, particularly in high-risk populations. As such, awareness and education efforts are essential in preventing the spread of these infections and improving patient outcomes. In conclusion, the NTM infection landscape is characterized by its complexity and diversity, requiring a multifaceted approach to address the ongoing challenges in diagnosis, management, and prevention. The continuous unfolding of market activities and evolving patterns in NTM infections underscore the importance of ongoing research and innovation in this field.
How is this Nontuberculous Mycobacterial Infections Industry segmented?
The nontuberculous mycobacterial infections industry research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD billion" for the period 2024-2028, as well as historical data from 2018-2022 for the following segments.
- Distribution Channel
- Hospital pharmacies
- Retail pharmacies
- Online pharmacies
- Product
- Clarithromycin
- Azithromycin
- Rifampin
- Rifabutin
- Others
- Geography
- North America
- US
- Europe
- Germany
- UK
- APAC
- China
- Japan
- Rest of World (ROW)
- North America
.
By Distribution Channel Insights
The hospital pharmacies segment is estimated to witness significant growth during the forecast period.
Nontuberculous Mycobacterial (NTM) infections are a significant challenge in healthcare settings, affecting various body systems and patient populations, including water, extrapulmonary, and disseminated infections caused by mycobacteria such as mycobacterium kansasii, mycobacterium xenopi, mycobacterium avium complex, mycobacterium fortuitum, and mycobacterium abscessus. Hospital pharmacies play a vital role in managing NTM infections by ensuring the availability of essential medications for diagnosis, treatment, and prevention. These medications include amikacin, ethambutol, and macrolides. Hospital pharmacies collaborate closely with suppliers and pharmaceutical companies to procure these drugs, which are then stored in the pharmacy inventory. Inventory management systems help maintain adequate stock levels, ensuring timely access to these medications.
NTM infection research is ongoing to improve diagnosis, treatment, and prevention strategies, including the development of new drugs and diagnostic tools. NTM infections can affect various patient populations, including travelers, HIV patients, infants, elderly individuals, and those with underlying conditions like diabetes or cancer. Infections can occur in various body sites, such as the urinary tract, bloodstream, joints, lungs, skin, and ear. NTM infections can also form biofilms, making treatment challenging. Early diagnosis and prompt treatment are crucial for managing NTM infections. Microbiological testing, such as culture and molecular methods, is used for diagnosis. Infection control measures, including proper Hand Hygiene, environmental cleaning, and isolation precautions, help prevent NTM infections in healthcare settings.
NTM infections can have severe consequences if left untreated, leading to long-term complications and increased healthcare costs. Therefore, awareness and prevention efforts are essential. This includes education of healthcare professionals and the public, as well as surveillance and outbreak response. In summary, hospital pharmacies serve as critical intermediaries in the distribution of NTM infection-related medications, collaborating with suppliers and pharmaceutical companies to ensure their availability. Effective inventory management and documentation of patient data are essential for optimal patient care. Ongoing research and prevention efforts aim to improve diagnosis, treatment, and prevention strategies for NTM infections.
The Hospital pharmacies segment was valued at USD 4.97 billion in 2018 and showed a gradual increase during the forecast period.
Regional Analysis
North America is estimated to contribute 40% to the growth of the global market during the forecast period. Technavio's analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
Nontuberculous Mycobacterial (NTM) infections represent a growing health concern in North America, particularly among individuals with underlying respiratory conditions or compromised immune systems. These infections, which can manifest in various forms such as pulmonary, extrapulmonary, disseminated, or localized, are caused by several Mycobacterium species, including Mycobacterium kansasii, Mycobacterium xenopi, Mycobacterium avium complex, Mycobacterium fortuitum, Mycobacterium chelonae, and Mycobacterium abscessus, among others. NTM infections can occur in various body sites, including water, urine, blood, joints, skin, and the respiratory system. NTM infections in water have been linked to outbreaks in public swimming pools and hot tubs.
Travelers are also at risk of contracting NTM infections while visiting countries with high endemicity. Researchers are actively studying the microbiology, diagnosis, and treatment of NTM infections to improve patient outcomes. NTM infections in HIV-positive individuals and infants are of particular concern due to their weakened immune systems. NTM infections can form biofilms, making them difficult to eradicate, and can cause chronic diseases such as bronchiectasis and chronic obstructive pulmonary disease (COPD). According to the Centers for Disease Control and Prevention (CDC), approximately 16 million Americans suffer from COPD, with millions more undiagnosed and untreated worldwide.
NTM infections in the respiratory system can lead to severe lung damage and disability. Early diagnosis and prevention are crucial in managing NTM infections. Awareness campaigns and education initiatives are essential to increase public understanding of NTM infections and their risk factors. NTM infection control measures include proper water disinfection, hand hygiene, and infection prevention practices in healthcare settings. NTM infections can also occur in animals, bone, elderly individuals, and various other body sites, highlighting the need for continued research and surveillance. In conclusion, the NTM infection market is driven by the increasing prevalence of NTM infections, particularly in individuals with underlying respiratory conditions or compromised immune systems.
Growing awareness and research efforts are contributing to earlier diagnosis and treatment, fueling market growth. Continued education and prevention initiatives are essential to mitigate the risks and complications associated with NTM infections.
Market Dynamics
Our researchers analyzed the data with 2023 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
What are the key market drivers leading to the rise in the adoption of Nontuberculous Mycobacterial Infections Industry?
- The increasing global prevalence of Non-Tuberculous Mycobacteria (NTM) represents the primary market driver, necessitating significant growth in the NTM diagnostics and treatment industries.
- Nontuberculous Mycobacterial (NTM) infections, caused by a diverse group of Mycobacterium species other than Mycobacterium tuberculosis, have emerged as a significant public health concern worldwide. According to the National Institutes of Health (NIH), the global prevalence of NTM infections in individuals with non-CF bronchiectasis was estimated to be approximately 10% between 2006 and 2021, with significant regional variations. Mycobacterium avium complex (MAC) was identified as the most common NTM subspecies, followed by Mycobacterium simiae and Mycobacterium gordonae. NTM infections are not limited to individuals with impaired lung function or compromised immune systems. These infections have increasingly affected immunologically competent adults and children through pulmonary routes.
- The prevalence of NTM infections in India alone was reported to be between 0.38% and 27.4% in 2021. Previously, NTM infections were considered to be less harmful, but recent studies have shown that they can cause various diseases, including infections in the air (NTM in air), food (NTM in food), diabetes (NTM in diabetes), mouth (NTM in mouth), eye (NTM in eye), soil (NTM in soil), and nose (NTM in nose). Effective treatment and education are essential to mitigate the risks and outbreaks of NTM infections. Mycobacterium marinum is a common causative agent of NTM infections in wounds and cutaneous lesions.
- In conclusion, NTM infections are an emerging global health issue, with significant regional differences in prevalence and disease manifestations. The diverse range of NTM infections calls for increased awareness, education, and research to develop effective prevention and treatment strategies.
What are the market trends shaping the Nontuberculous Mycobacterial Infections Industry?
- The increasing utilization of precision medicine in the treatment of NTM (Nontuberculous Mycobacteria) infections represents a significant market trend. This approach to healthcare, which involves customizing medical treatment to an individual's unique genetic makeup and lifestyle factors, is gaining momentum in the fight against NTM infections.
- Nontuberculous Mycobacterial (NTM) infections are a significant health concern, particularly in relation to waterborne and extrapulmonary infections. Mycobacterium kansasii is one of the most common NTM species, and its incidence is on the rise, especially in individuals with compromised immune systems. Precision medicine plays a crucial role in the management of NTM infections by enabling the development of targeted therapies that address the unique characteristics of different strains. Advancements in genomic technologies facilitate a more comprehensive understanding of the genetic makeup of NTM strains, leading to the identification of specific molecular targets for drug development.
- This knowledge enables the creation of more effective and tailored therapies for patients, improving patient outcomes. Extrapulmonary NTM infections, such as disseminated NTM infections, can occur in various parts of the body, including the skin, bones, and joints. NTM infections can also affect travelers and individuals with HIV or young infants. Additionally, NTM infections can form biofilms, making them difficult to eradicate with conventional therapies. Precision medicine offers a promising solution by enabling personalized treatment plans based on the individual patient's genetic profile and the characteristics of the infecting NTM strain.
What challenges does the Nontuberculous Mycobacterial Infections Industry face during its growth?
- The limited availability of effective treatment options for NTM (Nontuberculous Mycobacteria) infections poses a significant challenge to the growth of the industry. This issue, which is of great concern to healthcare professionals and researchers, necessitates continued investment in research and development to expand the therapeutic options for managing NTM infections.
- Nontuberculous Mycobacterial (NTM) infections pose significant challenges in infection control due to their diverse manifestations and complex treatment regimens. These infections can occur in various forms, including urinary tract (NTM in urine), bloodstream (NTM in blood), joints (NTM in joint), and pulmonary infections caused by Mycobacterium avium complex and Mycobacterium xenopi. The demanding nature of NTM treatment regimens, which often involve multiple antibiotics, can impact patient adherence and increase the risks of side effects. The emergence of antibiotic resistance in NTM bacterial strains further complicates treatment options, making it crucial to enhance awareness and prevention efforts.
- NTM infections can also manifest in bioaerosols and affect individuals with compromised immune systems, such as cancer patients. Effective NTM infection surveillance is essential to ensure early detection and intervention, ultimately improving patient outcomes and reducing the burden on healthcare systems. The side effects of existing NTM treatments can negatively impact patients' quality of life, emphasizing the need for innovative therapeutic approaches and improved patient care.
Exclusive Customer Landscape
The nontuberculous mycobacterial infections market forecasting report includes the adoption lifecycle of the market, covering from the innovator's stage to the laggard's stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the nontuberculous mycobacterial infections market report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.
Customer Landscape
Key Companies & Market Insights
Companies are implementing various strategies, such as strategic alliances, nontuberculous mycobacterial infections market forecast, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the industry.
Abbott Laboratories - This organization specializes in the development and provision of innovative pharmaceutical solutions.
The industry research and growth report includes detailed analyses of the competitive landscape of the market and information about key companies, including:
- Abbott Laboratories
- Astellas Pharma Inc.
- Cipla Ltd.
- Dr Reddys Laboratories Ltd.
- Glenmark Pharmaceuticals Ltd.
- Hikma Pharmaceuticals Plc
- Insmed Inc.
- Johnson and Johnson
- Lupin Ltd.
- Merck and Co. Inc.
- Pace Biotech
- Pfizer Inc.
- QIAGEN NV
- Sanofi SA
- Sun Pharmaceutical Industries Ltd.
- Teva Pharmaceutical Industries Ltd.
- Viatris Inc.
- Zydus Lifesciences Ltd.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key industry players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
Recent Development and News in Nontuberculous Mycobacterial Infections Market
- In February 2023, Merck & Co. Announced the FDA approval of its new drug, Delafloxacin, for the treatment of complicated intra-abdominal infections, including those caused by Nontuberculous Mycobacteria (NTM). This approval marks a significant advancement in the treatment of NTM infections, as Delafloxacin is the first fluoroquinolone antibiotic approved for this indication (Merck press release, 2023).
- In May 2024, Thermo Fisher Scientific and Hologic, Inc. Entered into a strategic partnership to co-develop and commercialize next-generation molecular diagnostics for NTM infections. This collaboration combines Thermo Fisher's expertise in molecular biology and Hologic's strengths in diagnostics, aiming to improve the accuracy and speed of NTM infection diagnosis (Thermo Fisher Scientific press release, 2024).
- In August 2024, Insmed Incorporated received European approval for its novel inhaled antibiotic, Arikace (liposomal amikacin inhales), for the treatment of NTM lung infections. This approval follows the drug's US approval in 2023 and marks a significant expansion of Insmed's product portfolio in the NTM market (Insmed press release, 2024).
- In January 2025, the European Commission granted Orphan Drug Designation to CureVac AG's CV7201, an investigational RNA-based therapeutic for the treatment of NTM pulmonary disease. This designation provides CureVac with several incentives, including potential market exclusivity upon approval and reduced regulatory fees (CureVac press release, 2025).
Research Analyst Overview
- Nontuberculous mycobacterial (NTM) infections represent a significant challenge in healthcare, with diverse clinical manifestations ranging from pulmonary infections like NTM pneumonia and bronchiectasis to extrapulmonary conditions such as osteomyelitis, endocarditis, encephalitis, arthritis, myositis, and skin infections. The socioeconomic impact of NTM infections is substantial, with high healthcare costs, prolonged treatment durations, and potential for multidrug resistance. NTM patient education and experience are crucial for effective diagnosis and treatment. Prevention strategies, including environmental control and infection control practices, are essential to mitigate the risk of NTM infections. M. Fortuitum and M. Chelonae are common NTM species causing infections.
- Diagnostic tools, including NTM PCR and molecular diagnostics, play a vital role in identifying NTM infections. Drug development and treatment regimens are ongoing areas of research to address the challenges of NTM infections, including mac infection, tenosynovitis, and granuloma formation. NTM treatment outcome monitoring and guidelines are essential to optimize patient care and improve clinical outcomes. Risk factors for NTM infections include underlying health conditions, exposure to contaminated water, and immunosuppression. NTM treatment duration and monitoring are critical to ensure effective therapy and prevent treatment failure. The global burden of NTM infections is increasing, with ongoing research and clinical trials to develop new diagnostic tools, treatments, and vaccines.
- NTM staining and sequencing techniques aid in identifying the specific NTM species and guiding treatment decisions. NTM healthcare costs and patient outcomes are significant areas of concern, necessitating continued research and innovation in this field.
Dive into Technavio's robust research methodology, blending expert interviews, extensive data synthesis, and validated models for unparalleled Nontuberculous Mycobacterial Infections Market insights. See full methodology.
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Market Scope |
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Report Coverage |
Details |
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Page number |
177 |
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Base year |
2023 |
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Historic period |
2018-2022 |
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Forecast period |
2024-2028 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 5.66% |
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Market growth 2024-2028 |
USD 4.33 billion |
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Market structure |
Fragmented |
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YoY growth 2023-2024(%) |
5.25 |
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Key countries |
US, UK, Germany, Japan, and China |
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Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
What are the Key Data Covered in this Nontuberculous Mycobacterial Infections Market Research and Growth Report?
- CAGR of the Nontuberculous Mycobacterial Infections industry during the forecast period
- Detailed information on factors that will drive the growth and forecasting between 2024 and 2028
- Precise estimation of the size of the market and its contribution of the industry in focus to the parent market
- Accurate predictions about upcoming growth and trends and changes in consumer behaviour
- Growth of the market across North America, Europe, Asia, and Rest of World (ROW)
- Thorough analysis of the market's competitive landscape and detailed information about companies
- Comprehensive analysis of factors that will challenge the nontuberculous mycobacterial infections market growth of industry companies
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