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The epigenetics market size is valued to increase by USD 1.48 billion, at a CAGR of 14.75% from 2023 to 2028. Rising epigenetic applications in non-oncology diseases will drive the epigenetics market.
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Epigenetics, a field of study focusing on modifications to gene expression without altering the DNA sequence, is revolutionizing precision medicine and cancer treatment. Epigenetic therapies, including CRISPR-Cas systems, RNA interference, and histone modification techniques, have shown promising results in gene silencing and expression regulation. For instance, histone deacetylases (HDACs) inhibitors have demonstrated a threefold increase in gene activation in preclinical trials, leading to improved therapeutic outcomes. Moreover, non-coding RNA, such as long non-coding RNA, plays a crucial role in epigenetic regulation, particularly in chromatin remodeling and cellular differentiation. In the realm of toxicological epigenetics, DNA methylation patterns and histone acetyltransferases have been instrumental in identifying epigenetic biomarkers for environmental exposures. Epigenomics data from genome-wide association studies and next-generation sequencing technologies enable a deeper understanding of epigenetic inheritance and developmental biology. Bioinformatics tools facilitate the analysis of complex epigenetic data, enabling targeted epigenetic drugs and epigenetic clocks to be developed for various applications.
The surge in epigenetic applications, particularly in the context of non-oncology diseases, is the primary market driver.
The life sciences industry is experiencing a significant trend towards technological advances. This mandated adaptation is shaping the upcoming market.
The lack of clinical validation poses a significant challenge to the growth of the direct-to-consumer genetic testing industry. This issue, which refers to the absence of rigorous scientific testing and approval by healthcare professionals, undermines the credibility and trustworthiness of these tests among consumers and healthcare providers alike. Consequently, addressing this challenge through increased regulatory oversight, standardized testing protocols, and collaboration between industry stakeholders is essential to fostering industry growth and ensuring the accuracy and reliability of direct-to-consumer genetic testing services.
The epigenetics industry research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD million" for the period 2024-2028, as well as historical data from 2018-2022 for the following segments.
The oncology segment is estimated to witness significant growth during the forecast period.
The market continues to evolve as research advances in various areas, including epigenome editing, precision medicine, and cancer epigenetics. Epigenetic therapies, such as RNA interference, CRISPR-Cas systems, and histone modification, are increasingly used for gene silencing and expression regulation. Non-coding RNA plays a crucial role in epigenetic regulation, with long non-coding RNA and histone deacetylases influencing chromatin accessibility and gene activation. Epigenetic clocks, genome-wide association studies, and next-generation sequencing provide valuable data for understanding epigenetic inheritance and developmental biology. Toxicological epigenetics and environmental epigenetics are emerging fields that investigate the impact of external factors on epigenetic regulation.
Epigenetic biomarkers offer potential for early disease detection and diagnosis, with methylation-specific PCR (MSP) being an example for identifying abnormal methylation patterns in cancer. Approximately 70-80% of human diseases have an epigenetic component, making this field essential for understanding disease development and progression.
The Oncology segment was valued at USD 504.06 billion in 2018 and showed a gradual increase during the forecast period.
North America is estimated to contribute 39% to the growth of the global market during the forecast period.Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
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The market is experiencing significant growth, driven by the rising incidence of chronic diseases and increasing healthcare expenditure. With numerous biotechnology and life sciences companies headquartered in North America, particularly in the US and Canada, the region dominates the global market. These companies export epigenetics instruments to other regions, enabling emerging companies in Asia and South America to offer epigenetics services locally.
The high number of clinical trials in North America, accounting for 31% of the total worldwide as of February 2023 (NIH), further fuels the demand for epigenetics in drug development. This market's evolution is marked by operational efficiency gains and cost reductions, making epigenetics a crucial component in healthcare research and innovation.
Customer Landscape of Epigenetics Industry
Companies are implementing various strategies, such as strategic alliances, epigenetics market forecast, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the industry.
Abcam Plc - Epigenetics research is a specialized field focusing on modifications to gene expression without altering the DNA sequence itself. This approach offers valuable insights into biological processes and potential therapeutic applications. The company in question is a pioneer in this area, conducting comprehensive studies to advance scientific understanding and drive innovation.
The industry research and growth report includes detailed analyses of the competitive landscape of the market and information about key companies, including:
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key industry players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
Dive into Technavio’s robust research methodology, blending expert interviews, extensive data synthesis, and validated models for unparalleled Epigenetics Market insights. See full methodology.
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Market Scope |
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Report Coverage |
Details |
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Page number |
163 |
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Base year |
2023 |
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Historic period |
2018-2022 |
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Forecast period |
2024-2028 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 14.75% |
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Market growth 2024-2028 |
USD 1477.78 million |
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Market structure |
Fragmented |
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YoY growth 2023-2024(%) |
13.54 |
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Key countries |
US, Canada, Germany, UK, China, Japan, South Korea, Netherlands, UAE, Brazil, and Rest of World(ROW) |
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Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
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The market is experiencing significant growth as research in this field continues to unravel the complex interplay between genetic and environmental factors in various biological processes. Histone modification patterns in cancer and DNA methylation in aging processes are key areas of focus, with epigenetic alterations implicated in the development and progression of these conditions. Non-coding RNA's role in development and its impact on chromatin remodeling and gene expression are also subjects of intense study. In neurodegenerative diseases, epigenetic drug targets are being explored to mitigate the effects of these conditions. Environmental factors, such as diet and toxins, are known to influence epigenetic changes, making it a critical area for research in understanding disease risk and prevention. The epigenome editing technologies and applications, including CRISPR-Cas9, are revolutionizing the field, enabling precise modifications to epigenetic marks. These advancements have significant implications for therapeutic applications, including epigenetic reprogramming in stem cells and clinical applications of epigenetic testing for early disease detection. Next-generation sequencing and bioinformatics tools are essential for epigenomic analysis, enabling the interpretation of vast amounts of data generated from epigenetic studies. Regulatory elements controlling gene expression and epigenetic modifications in response to toxins are areas of active research, with potential implications for compliance and operational planning in industries with significant environmental exposures. The impact of dietary compounds on epigenetic marks is another area of interest, with indirect comparisons suggesting that certain nutrients may influence epigenetic patterns in ways that promote health or disease. Epigenetic drug resistance mechanisms are also being studied, with potential implications for supply chain optimization in the pharmaceutical industry. In summary, the market is a dynamic and rapidly evolving field, with significant implications for healthcare, agriculture, and other industries. The ability to modify epigenetic marks offers a new frontier for disease prevention, treatment, and understanding the complex interplay between genetics and the environment.
What is the expected growth of the Epigenetics Market between 2024 and 2028?
USD 1.48 billion, at a CAGR of 14.75%
What segmentation does the market report cover?
The report is segmented by Application (Oncology, Non-oncology, Cardiovascular Diseases, Developmental Biology, Immunology, and Metabolic Diseases), Product (Reagents, Kits, Enzymes, Instruments, Software, Services, and others), Geography (North America, Europe, Middle East and Africa, Asia, South America, and Rest of World (ROW)), Technology (DNA Methylation, Histone Methylation, Histone Acetylation, Large non-coding RNA, MicroRNA modification, Chromatin structures, Bisulfite Sequencing, Next-Generation Sequencing (NGS), PCR-based Methods, and Chromatin Remodeling), and End-Use (Academic Research, Clinical Research, Hospitals & Clinics, Pharmaceutical & Biotechnology Companies, Other, Contract Research Organizations (CROs), and Diagnostic Laboratories)
Which regions are analyzed in the report?
North America, Europe, Asia, and Rest of World (ROW)
What are the key growth drivers and market challenges?
Rising epigenetic applications in non-oncology diseases, Lack of clinical validation on direct-to-consumer genetic tests
Who are the major players in the Epigenetics Market?
Abcam Plc, Active Motif Inc., Agilent Technologies Inc., Bio-Rad Laboratories Inc., CellCentric, Chroma Therapeutics, Diagenode (Hologic), EpiGentek Group Inc., F. Hoffmann-La Roche Ltd., Illumina Inc., Merck KGaA, New England Biolabs, PerkinElmer Inc., Promega Corporation, Qiagen N.V., Syndax Pharmaceuticals, Takara Bio Inc., Thermo Fisher Scientific Inc., Zymo Research Corporation, and ZymoGenetics Inc.
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Application
7 Market Segmentation by Product
8 Market Segmentation by Technology
9 Market Segmentation by End-Use
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
14 Competitive Analysis
13 Appendix
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
Secondary sources
DATA ANALYSIS
Data Synthesis
Data Validation
REPORT WRITING
Qualitative
Quantitative
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