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The global immunoprecipitation market size is estimated to grow by USD 270.1 million, at a CAGR of 6.01% between 2023 and 2028.
Immunoprecipitation plays a pivotal role in antigen purification and downstream processing, impacting both time and cost. Market trends show continuous efforts to enhance productivity and efficiency. Developments in large-scale chromatography processes include novel resin properties, improved protein resin for mAb capture, single-use technologies, exploring commercial-scale continuous chromatography, and automation. The shift to modern immunoprecipitation-based production processes emphasizes large-scale capabilities, targeting challenges in purifying mAbs, blood factors, antibody fragments, gene therapy vectors, and viral vaccines. Mass chromatography, binding with immunoglobulin G segments, enhances immunoprecipitation efficacy in purifying standard mAbs. Growing research and development in biopharmaceuticals indicate increased immunoprecipitation adoption, driving the market's growth during the forecast period.
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The market encompasses a wide array of products and services catering to researchers and pharmaceutical & biotechnology companies engaged in drug development, disease study, and immunotherapy. Key components include kits, IP assays, antigens, proteins, and antibodies facilitating the study of protein-protein interactions and disease mechanisms related to autoimmune diseases and oncology. Advanced techniques like Chromatin Immunoprecipitation (ChIP) technology, ChIP-seq, and RNA immunoprecipitation offer insights into genomics, epigenetics, and individual immunoprecipitation. The market also sees applications in cellular and genetic therapies, with technological advancements driving innovation in immunology and immuno-oncology. Pharmaceutical & biotechnology companies are major players in this market, leveraging Chromatrap Immunoprecipitation and co-immunoprecipitation techniques for drug discovery. Collaboration with federal bodies and integration into the healthcare sector further bolsters market growth, fostering a dynamic landscape for immunoprecipitation products and services.
The market share growth by the academic and research institutes segment will be significant during the forecast period. Academic and research institutes segment include the use of fluidic technology for research purposes, such as microfluidics research, neuroscience research, cellular research, and other life science experiments involving chromatography and mass spectrometry.
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The academic and research institutes segment was the largest and was valued at USD 293.62 million in 2018. Research institutes are the centers where tests are performed on clinical specimens for monitoring patients' health related to the diagnosis, treatment, and prevention of various neurological disorders. Moreover, laboratories get references to conduct tests and clinical trials from pharmaceutical and biotechnology companies, corporate offices, and insurance companies. Hospitals, companies, and clinics refer the tests to reference research institutes to reduce the data management cost. Research centers are linked to national and international universities and medical centers to conduct clinical research. Therefore, increasing R&D on neuroscience antibodies is expected to drive the growth of the academic and research institutes segment and boost the growth of the market during the forecast period.
Chromatin immunoprecipitation (ChIP) is a pivotal technique within the global immunoprecipitation market, used to understand and analyze the complex interactions between proteins and deoxyribonucleic acid (DNA). This method enables researchers to investigate the binding patterns of proteins, such as transcription factors and histones, to specific DNA sequences, along with the entire genome, thus helping in providing a better understanding of their regulatory functions and mechanisms. As the demand for precision medicine grows, the ChIP technique becomes integral in exploring epigenetic contributions to diseases, opening avenues for developing targeted therapies. Such factors are expected to fuel the growth of the chromatin immunoprecipitation segment, which will thereby drive the growth of the global immunoprecipitation market during the forecast period.
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North America is estimated to contribute 42% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that will shape the market during the forecast period. North America, particularly the US and Canada, boasts world-class research institutions, universities, and medical centres. Globally, North America is the largest market for immunoprecipitation and is estimated to show significant growth. This is attributed to the ever-increasing demand for pharmaceutical drugs and products. There is also an increasing demand for immunoprecipitation from biotechnological firms, academic institutes, and research institutes. The strong distribution networks in countries such as the US and Canada and the increasing focus of pharmaceutical companies on drug discovery and development are driving the growth of the regional market.
In addition, organizations such as the National Institutes of Health and the Biomedical Advanced Research and Development Authority have also increased their funding for such research. These organizations provide funding to progress clinical trials and develop new medicines for various diseases, which increase the demand in the region. The growth of monoclonal antibody therapeutics usage in the region is strong and is likely to increase the demand for immunoprecipitation during the forecast period. The increased use of modern chromatography techniques for food analysis and diagnostic purposes is also anticipated to drive regional market growth during the forecast period.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about 20 market companies, including:
Active Motif Inc - The company offers immunoprecipitation products such as ChIP-IT Express Chromatin Immunoprecipitation Kits which provides a streamlined protocol using protein G-coated magnetic beads, making it possible to perform ChIP in just 1 day.
Active Motif Inc., Agilent Technologies Inc., Becton Dickinson and Company, Bio Rad Laboratories Inc., Cell Signaling Technology Inc., Chargen Life Sciences LLP, CLOUD CLONE CORP., Creative Biolabs, Danaher Corp., GenScript Biotech Corp., JSR Micro Inc., Merck KGaA, OriGene Technologies Inc., PerkinElmer Inc, Proteintech Group Inc., Rockland Immunochemicals Inc., Santa Cruz Biotechnology Inc., Sino Biological Inc., and Thermo Fisher Scientific Inc.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The market thrives on a surge in research involving Kits, IP assays, and Antigens. Protein-protein interactions are crucial in unveiling disease mechanisms and aiding drug development. Researchers leverage cutting-edge techniques in Immunotherapy, Genomics, and Microbiome studies, advancing the understanding of various diseases. Federal bodies' support fuels healthcare sectors, especially in Oncology and Immunology, while immuno-oncology gains prominence. Technological strides, such as Chromatin Immunoprecipitation techniques and innovative tools like Chromatrap Immunoprecipitation (ChIP) technology, enhance epigenetic studies. Challenges include optimizing ChIP-seq, individual immunoprecipitation, and co-immunoprecipitation methods, ensuring the efficacy of RNA immunoprecipitation amid diverse applications. Antibodies and beads play pivotal roles, with pharmaceutical and biotechnology companies driving innovation. Our researchers analyzed the market research and growth data with 2023 as the base year, along with the key market growth analysis, trends, and challenges. A holistic analysis of trends and challenges will help companies refine their marketing strategies to gain a competitive advantage.
The rising number of genome projects is an emerging trend shaping market growth. In recent years, a surge in genome projects, exemplified by the 2020 initiation of the Human Genome Project (HGP) in India, underscores the global effort to comprehend the human genome. These projects, illuminating genetic variations and disease-causing mutations specific to populations, contribute to creating genetic maps. Researchers leverage genome projects to unravel gene and protein functions, particularly vital in medicine, biotechnology, and life sciences.
Moreover, the expanding significance of genome projects propels researchers into genomics, where epigenetics solutions uncover the intricate role of DNA and genes in human ailments. Pharmacogenomics, an advancing field designing personalized medicine based on genetic makeup, promises substantial growth. The intensifying focus on genome projects is steering the widespread adoption of immunoprecipitation techniques, particularly for applications like DNA sequencing, fostering the market during the forecast period.
The lack of skilled professionals is a significant challenge hindering market growth. The selection of an immunoprecipitation technique for complex mixture analysis necessitates careful consideration of factors such as chemical composition, nature, and physical properties of the target substance. The appropriate technique choice significantly influences the purification process's efficacy, impacting direct and indirect expenses and time to market. Despite the advent of advanced technologies, a shortage of skilled professionals proficient in chromatography equipment and operations poses a challenge.
Additionally, optimal equipment utilization is critical, and inconsistencies, like column packing issues, can compromise product yield and purity. Training programs become essential, yet recruiting experienced personnel remains challenging, limiting immunoprecipitation adoption. The scarcity of skilled professionals is anticipated to impede the market's growth during the forecast period.
The market forecasting report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth and forecasting strategies.
Customer Landscape
The market report forecasts market growth by revenue at global, regional & country levels and provides an analysis of the latest trends and growth opportunities from 2018 to 2028.
The market exhibits a robust outlook driven by an extensive array of applications across the life sciences industry. Fueled by advancements in modern genetic techniques and research activities, individual immunoprecipitation plays a pivotal role in studying autoimmune diseases, antigen-antibody interactions, and genomics research. Pharmaceutical and biotechnology companies, along with academic and research institutes, are key end-users, leveraging primary antibodies, secondary antibodies, agarose beads, and buffers for varied applications. The market's growth is further accelerated by R&D activities addressing diseases like central nervous disorders, cancers, and cardiovascular diseases.
Moreover, the notable contributors include the National Institute of Allergy and Infectious Diseases (NIAID) and the International Agency for Research on Cancer (IARC), emphasizing the market's significance in cutting-edge research initiatives. The advent of innovative technologies like Chromatrap and applications in SARS-CoV2 infection underscores immunoprecipitation's pivotal role in addressing contemporary healthcare challenges. The market's trajectory aligns with ongoing advancements and research pursuits across diverse scientific domains.
Market Scope |
|
Report Coverage |
Details |
Page number |
161 |
Base year |
2023 |
Historic period |
2018-2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 6.01% |
Market Growth 2024-2028 |
USD 270.1 million |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
5.39 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 42% |
Key countries |
US, Canada, UK, Germany, and China |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
Active Motif Inc., Agilent Technologies Inc., Becton Dickinson and Company, Bio Rad Laboratories Inc., Cell Signaling Technology Inc., Chargen Life Sciences LLP, CLOUD CLONE CORP., Creative Biolabs, Danaher Corp., GenScript Biotech Corp., JSR Micro Inc., Merck KGaA, OriGene Technologies Inc., PerkinElmer Inc, Proteintech Group Inc., Rockland Immunochemicals Inc., Santa Cruz Biotechnology Inc., Sino Biological Inc., and Thermo Fisher Scientific Inc. |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by End-user
7 Market Segmentation by Type
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
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