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The Protein Expression Market size is estimated to grow by USD 3.4 billion at a CAGR of 16.1% between 2023 and 2028. Studying proteins raises the understanding of post-translational modifications, thus, improving the knowledge of functional proteins. There has been a growing number of initiatives to accelerate research on protein engineering. Innovations such as the evolution of highly tolerant beans that can be grown in extreme conditions are possible due to extensive protein research, which requires protein assays. The growing acceptance of proteomics research is largely a result of technological progress in this area. Advances such as parallel sample processing, modern spotting techniques, and miniaturization approaches encourage researchers to pursue this field for multiple applications such as drug discovery outsourcing, diagnostics, and the production of proteins like enzymes and antibodies.
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Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about key companies, including:
Agilent Technologies Inc.- The company offers Protein expression solutions through its Protein expression transfection reagent and kits such as GeneJammer, Mammalian Transfection kit, and ViraPack Transfection kit.
Agilent Technologies Inc., Amgen Inc., Becton Dickinson and Co., Bio Rad Laboratories Inc., Bioneer Corp., Danaher Corp., GenScript Biotech Corp., LGC Science Group Holdings Ltd., Lonza Group Ltd., Merck and Co. Inc., New England Biolabs Inc., Oxford Expression Technology Ltd., Pfizer Inc., Promega Corp., QIAGEN NV, Sartorius AG, Sino Biological Inc., Synbio Technologies, Takara Holdings Inc., and Thermo Fisher Scientific Inc.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The market share growth by the products segment will be significant during the forecast period. Instruments and consumables are among the products that form part of the market for proteomic studies. Consumables include biotechnology reagents, kits, buffers, dyes, probes, and chemicals that are intended to be used for a limited period as they do not have long shelf lives.
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The product segment was valued at USD 1.01 billion in 2018. Consumables are less expensive when compared with the cost of instruments, thus increasing their demand. To make it easier for researchers to buy consumables such as reagents in bulk, vendors are offering a discount on the supplies. The increase in proteomic studies will also contribute to the rise in demand for consumables, thereby supporting the growth of the market in focus throughout the forecast period.
Pharmaceutical and biotechnological companies play a significant role in the global market due to their involvement in the research, development, and production of therapeutic proteins, enzymes, and other biologically active molecules. The major process of protein expression is the synthesis and manufacture of individual proteins, which are applicable for a wide variety of applications such as drug discovery, diagnostics, and industrial processes. Pharmaceutical companies utilize protein expression technologies to produce therapeutic proteins, antibodies, and enzymes that are essential for drug discovery and development. To advance the development of drugs, improve healthcare for patients, and drive innovation within the life science industry, investment in the technology is being made by pharmaceuticals and biotechnological companies. Such factors will propel the growth of the market in focus during the forecast period.
Academic research plays a crucial role in the global market by contributing to the advancement of knowledge, innovation, and the development of new techniques and technologies. Several issues related are contributed by researchers at universities throughout the world, from the fundamental understanding of biological processes to the development of novel applications. Moreover, basic mechanisms, transcription, translation, and after translational modifications are investigated by researchers in academia. However, academic research will fuel innovation, drive technological advancements, and expand the understanding of protein expression, stimulating market focus growth during the forecast period.
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North America is estimated to contribute 37% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional market trends and analysis and drivers that will shape the market during the forecast period. The region is receiving increased amounts of funds through investments in protein research by asset management firms, which support the research and its applications. This investment results in increased returns on their respective investments. With the development of advanced protein research in these countries, the US and Canada are becoming major revenue contributors to this region. Extensive research is conducted on protein quantitation and expression, which forms the basis for several proteomics research projects. The ACA is a member society of the American Institute of Physics and a Regional Associate of the International Union of Crystallography that promotes interactions among scientists who study the structure of matter at atomic resolutions. These interactions contribute to the advances in experimental and computational research.
The market is driven by the growing demand for protein biologics and protein therapeutics for treating chronic diseases like cardiovascular diseases and rheumatoid arthritis. Innovations in genetic engineering and protein engineering are enhancing the production of recombinant proteins. Companies like Vicinitas Therapeutics, BioIVT, and Cypex lead in providing advanced protein expression reagents. Webinars and resources from the World Health Organization and industry leaders such as Arbor Biosciences, Promega Corporation, and Aviva Systems Biology highlight market trends. Challenges include optimizing cell-free expression systems and improving protein-protein interaction studies and biomarkers for effective treatments. Our researchers analyzed the market research and growth data with 2023 as the base year, along with the key market growth analysis, trends, and challenges. A holistic analysis of drivers, trends, and challenges will help companies refine their marketing strategies to gain a competitive advantage.
The rise in usage in the food industry is driving growth in the market. It is a method of analyzing the protein content in food and ingredients, which are essential to ensure the quality and safety of food. Protein-based foods are contaminated with melamine and other non-protein substances. This contamination can lead to injury and death of infants who consume adulterated milk formula and can cause harm to pets who consume adulterated pet food.
Moreover, the determination in food in the presence of heat is essential to make accurate nutritional claims. Heat is one of the major factors affecting the concentration of proteins. The texture and composition of many processed food products can be affected by changes that take place. Therefore, monitoring these changes with the help of the products is essential, which will increase the demand for the products and services and benefit the market in focus during the forecast period.
The increasing importance of promotional activities is a key trend in the market. Marketing of these products is challenging because of their niche request and regulatory restrictions. Brand and product visibility have a limited role to play in the sales of the products, compared with other analytical instruments. Emphasis is laid on improving distribution networks and increasing the availability of products to end-users.
However, advertising and marketing of these products are restricted, and the lack of awareness about such products is significant. Therefore, to raise awareness of these products, companies are promoting the use of these products via their websites. As product enhancements continue in the market, vendors realize the importance of promotional activities, and this trend is set to increase in the market focus during the forecast period.
The lack of skilled laboratory professionals is a major challenge faced by the market. The techniques for the expression of proteins are technically complex, and care is needed to produce reliable results. The use of such products is increasing rapidly. A major challenge in these scientific fields is the lack of technically skilled and trained staff.
However, as laboratories are under pressure to deliver rapid results under decreased turnaround times, training programs for laboratory professionals are neglected. Several factors contribute to a shortage of laboratory professionals, including the fact that there is little recognition of this profession and an inadequate understanding of its importance, which is expected to continue during the forecast period, thereby offsetting the market growth and trends during the market forecast period.
The market forecast report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the market analysis and report also include key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market forecasting and market growth and forecasting market strategies.
Customer Landscape
The market research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD billion " for the period 2024-2028, as well as historical data from 2018 - 2022 for the following segments.
The market is significantly influenced by the biopharmaceutical industries focusing on growth dynamics to address diseases like cancer and autoimmune diseases. The development of novel drugs such as monoclonal antibodies (mAbs) including Tocilizumab, Sotrovimab, Bamlanivimab, and Etesevimab, approved under EUA, along with Evusheld (Tixagevimab and Cilgavimab), demonstrates the market's expansion. Advances in microfluidics, heterologous production, and the use of efficient production hosts like Corynebacterium glutamicum enhance protein expression studies. Challenges include protein purification, dealing with misfolded proteins, and protein degradation. Key system segments like mammalian expression systems, prokaryotic expression systems, insect cell expression systems, and yeast expression systems are vital for biopharmaceutical companies. The therapeutic segment within the biologics market sees significant contributions from companies producing antibodies and protein therapeutics such as Hulio biosimilar. However, the market faces stringent regulations impacting the pipelines of protein therapeutic developments and antibody production companies.
Market Scope |
|
Report Coverage |
Details |
Base year |
2023 |
Historic period |
2018-2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 16.1% |
Market Growth 2024-2028 |
USD 3.40 billion |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
13.51 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 37% |
Key countries |
US, UK, China, Germany, and Japan |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
Agilent Technologies Inc., Amgen Inc., Becton Dickinson and Co., Bio Rad Laboratories Inc., Bioneer Corp., Danaher Corp., GenScript Biotech Corp., LGC Science Group Holdings Ltd., Lonza Group Ltd., Merck and Co. Inc., New England Biolabs Inc., Oxford Expression Technology Ltd., Pfizer Inc., Promega Corp., QIAGEN NV, Sartorius AG, Sino Biological Inc., Synbio Technologies, Takara Holdings Inc., and Thermo Fisher Scientific Inc. |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for the forecast period. |
Customization purview |
If our market report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Solution
7 Market Segmentation by End-user
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Opportunity/Restraints
11 Competitive Landscape
12 Competitive Analysis
13 Appendix
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