Mass Spectrometry Market Analysis, Size, and Forecast 2025-2029: North America (US and Canada), Europe (France, Germany, and UK), APAC (China, India, and Japan), South America (Argentina and Brazil), and Rest of World (ROW)

Mass Spectrometry Market Size 2025-2029

The mass spectrometry market size is forecast to increase by USD 4.28 billion, at a CAGR of 13.2% between 2024 and 2029. Increase in use of hyphenated technology will drive the mass spectrometry market.

Major Market Trends & Insights

• North America dominated the market and accounted for a 43% growth during the forecast period.
• By End-user - P and B industries segment was valued at USD 1.54 billion in 2023
• By Product - Instruments segment accounted for the largest market revenue share in 2023

Market Size & Forecast

• Market Opportunities: USD 177.04 billion
• Market Future Opportunities: USD USD 4.28 billion 
• CAGR : 13.2%
• North America: Largest market in 2023

Market Summary

• The market is a dynamic and evolving sector, driven by the increasing use of hyphenated technologies such as tandem mass spectrometry and time-of-flight mass spectrometry. These advanced technologies are fueling the demand for mass spectrometers in various applications, including pharmaceuticals, food and beverage industries, and personalized medicine. However, the high cost of mass spectrometry instruments remains a significant challenge for market growth. According to recent studies, the market is expected to continue expanding in the coming years, with personalized medicine applications accounting for a substantial market share. For instance, the adoption rate of mass spectrometry in personalized medicine is projected to reach 15% by 2025.
• In related markets such as proteomics and metabolomics, the demand for mass spectrometry instruments is also on the rise. Despite these opportunities, regulatory compliance and data interpretation challenges pose significant hurdles for market participants. Key companies in the market include Thermo Fisher Scientific, Agilent Technologies, and Bruker Corporation.

What will be the Size of the Mass Spectrometry Market during the forecast period?

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How is the Mass Spectrometry Market Segmented and what are the key trends of market segmentation?

The mass spectrometry industry research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD million" for the period 2025-2029, as well as historical data from 2019-2023 for the following segments.

• End-user
  • P and B industries
  • Chemical and petrochemical industries
  • Others
• Product
  • Instruments
  • Consumables and services
• Technology
  • QLC-MS
  • GC-MS
  • FT-MS
  • ToFMS
  • Others
• Geography
  • North America
    • US
    • Canada
  • Europe
    • France
    • Germany
    • UK
  • APAC
    • China
    • India
    • Japan
  • South America
    • Argentina
    • Brazil
  • Rest of World (ROW)

By End-user Insights

The p and b industries segment is estimated to witness significant growth during the forecast period.

Mass spectrometry is a crucial analytical technique in the pharmaceutical and biotechnology industries, driving significant market growth due to its ability to determine molecular structures and purity. In these sectors, mass spectrometry is employed to characterize therapeutic agents, understand the structural properties of complex molecules like unfolded proteins and carbohydrates, and investigate intermolecular interactions for drug discovery. The technique's versatility extends to measuring large molecule dynamics and their role in biological functions, such as protein folding, intermolecular signaling, and catalysis. Key mass spectrometry techniques include data-independent acquisition, high-resolution mass spectrometry, neutral loss scanning, peptide mass fingerprinting, and quadrupole time-of-flight.

These methods are integral to metabolomics data analysis, protein identification software, and the proteomics workflow. Innovations like ion mobility spectrometry, selected reaction monitoring, and tandem mass spectrometry further enhance mass spectrometry's capabilities, enabling product ion scanning, metabolite profiling, and mass spectrometry imaging. These advancements expand the technique's dynamic range and improve quantitative mass spectrometry, addressing the demands of the pharmaceutical and biotechnology industries. Mass spectrometry applications extend beyond the P and B industries, with techniques like gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry gaining popularity in various sectors. The mass resolution and accuracy offered by mass spectrometry, including orbitrap mass analyzers and time-of-flight mass spectrometry, make it an indispensable tool for research and development.

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The P and B industries segment was valued at USD 1.54 billion in 2019 and showed a gradual increase during the forecast period.

The market is expected to grow substantially, with an increase of approximately 15% in industry adoption and 18% in future expectations. This growth is fueled by the continuous evolution of mass spectrometry techniques and their applications across diverse industries. In summary, mass spectrometry is a vital analytical technique in the pharmaceutical and biotechnology industries, driving market growth through its ability to determine molecular structures and purity. Its versatility and ongoing advancements make it an indispensable tool for research and development across various sectors.

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Regional Analysis

North America is estimated to contribute 43% to the growth of the global market during the forecast period. Technavio's analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.

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The market in North America, primarily driven by the US, experiences growth due to the heightened focus on drug discovery and development in numerous pharmaceutical companies. Key players, such as Novartis International AG and Pfizer Inc., based in the US, are leading this expansion. These companies, with a significant presence in the region, invest heavily in research activities for drug production and vaccine manufacturing.

In 2024, PhRMA members allocated approximately USD 102.38 billion towards research and development, marking an increase of 18%. This investment underscores the continuous evolution of the market, with a growing demand for mass spectrometers in pharmaceutical research and development.

Market Dynamics

The mass spectrometry market is characterized by a drive for enhanced resolution and sensitivity, which is crucial for complex analytical challenges. Liquid chromatography coupled mass spectrometry metabolite identification and tandem mass spectrometry protein quantification methods are fundamental to this progress.

For instance, triple quadrupole mass spectrometry targeted analysis offers a high degree of specificity, with some systems demonstrating up to a 15-fold increase in sensitivity for quantifying specific compounds. The performance of analyzers like the Orbitrap mass analyzer is a key differentiator, with a maximum resolution of up to 1,000,000 FWHM at m/z 200, which is significantly higher than alternative technologies.

This capability is vital for high-resolution mass spectrometry peptide sequencing and lipid profiling using time of flight mass spectrometry. Furthermore, the market for mass spectrometry based proteomics clinical applications is seeing strong growth, with hybrid instruments expected to account for over 42% of revenue share. The use of ion mobility spectrometry enhanced separation and data independent acquisition metabolomics workflow is also expanding, enabling more comprehensive analysis and helping researchers identify a greater number of proteins with a 1% protein group-level false discovery rate.

What are the key market drivers leading to the rise in the adoption of Mass Spectrometry Industry?

• The significant rise in the adoption of hyphenated technologies is the primary catalyst fueling market growth. 

• Hyphenation technology, specifically Liquid Chromatography-Mass Spectrometry (LC-MS), has gained significant traction in various industries due to its unique ability to combine separation and mass characterization in a single analytical process. This innovative approach has led to increased adoption, particularly in sectors such as pharmaceuticals, forensics, and food analysis. LC-MS plays a pivotal role in the detection of steroid drugs in bodily fluids and profiling endogenous steroids. In healthcare, newborn babies' blood samples are analyzed using LC-MS to identify metabolic disorders. The technology's versatility extends to determining pharmaceutical compounds, with a focus on separating optically active drugs.
• The integration of LC and MS has revolutionized analytical chemistry, offering enhanced sensitivity, selectivity, and accuracy. As a result, LC-MS has become an indispensable tool for businesses seeking to optimize their processes and ensure product quality. Its impact is felt across numerous industries, from environmental analysis to the development of advanced materials. In summary, LC-MS represents a game-changing technology that has transformed the analytical landscape by enabling simultaneous separation and mass characterization. Its applications span various sectors, making it a valuable asset for businesses seeking to innovate and maintain a competitive edge.

What are the market trends shaping the Mass Spectrometry Industry?

• The rising demand for mass spectrometers in personalized medicine represents a significant market trend. Mass spectrometry plays a crucial role in the advancement of personalized medicine due to its ability to identify and quantify various biomolecules, enabling precise diagnosis and treatment plans.

• Personalized medicine, a dynamic and evolving approach to healthcare, is revolutionizing patient care by customizing medical treatment based on individual patient characteristics. This multi-faceted approach enhances disease diagnosis and treatment, offering the potential for earlier detection and effective intervention. Predictive diagnostics, a crucial component of personalized medicine, plays a pivotal role in targeted preventive measures and the development of individualized treatment plans.
• By predicting human pathologies, predictive diagnostics aid in establishing a treatment timeline tailored to the patient's needs. Misdiagnosis can have severe consequences, making predictive diagnosis essential in screening patients for appropriate treatments. The ongoing advancements in personalized medicine continue to unfold, with predictive diagnostics leading the charge in delivering more effective and efficient patient care.

What challenges does the Mass Spectrometry Industry face during its growth?

• The high cost of mass spectrometry instruments poses a significant challenge to the industry's growth, as these sophisticated tools are essential for advanced scientific research and analysis in various sectors, including healthcare, pharmaceuticals, and materials science. 

• Mass spectrometers, essential analytical tools in various industries, exhibit significant costs due to their high purchase prices and ongoing maintenance requirements. On average, these instruments cost between USD 1,000 and USD 100,000, with standard models commanding higher maintenance, service, and repair expenses, thereby increasing their total cost of ownership. This financial burden can hinder mass spectrometer adoption, especially in sectors with tight budgets. Despite these challenges, the versatility and precision of mass spectrometers make them indispensable for applications in fields like pharmaceuticals, food and beverage, and environmental analysis.
• Their ability to identify and quantify complex molecules drives continuous innovation and expansion within these industries. The total cost of ownership, a crucial consideration for businesses, underscores the importance of optimizing mass spectrometer usage and implementing cost-effective maintenance strategies.

Exclusive Customer Landscape

The mass spectrometry market forecasting report includes the adoption lifecycle of the market, covering from the innovator's stage to the laggard's stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the mass spectrometry market report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.

 Customer Landscape of Mass Spectrometry Industry

Competitive Landscape & Market Insights

Companies are implementing various strategies, such as strategic alliances, mass spectrometry market forecast, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the industry.

908 Devices Inc. - The company specializes in mass spectrometry technologies, including Maven, Rebel, and ZipChip, delivering innovative solutions for various industries by providing accurate and efficient analysis of molecular structures. 

The industry research and growth report includes detailed analyses of the competitive landscape of the market and information about key companies, including:

• 908 Devices Inc.
• ABB Ltd.
• Agilent Technologies Inc.
• Bruker Corp.
• Endress Hauser Group Services AG
• JEOL Ltd.
• Kore Technology Ltd.
• LECO Corp.
• MOBILion Systems Inc.
• Perkin Elmer Inc.
• Rigaku Corp.
• Shimadzu Corp.
• Teledyne Technologies Inc.
• Thermo Fisher Scientific Inc.
• Waters Corp.

Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key industry players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.

Recent Development and News in Mass Spectrometry Market

• In January 2024, Thermo Fisher Scientific, a leading life sciences solutions provider, announced the launch of its new Triple Quad 7500 GC-MS/MS System. This innovative mass spectrometer combines gas chromatography and mass spectrometry capabilities, enabling enhanced sensitivity and accuracy for complex analysis in industries such as food and environmental testing (Thermo Fisher Scientific Press Release, 2024).
• In March 2024, Agilent Technologies, a prominent player in the market, entered into a strategic collaboration with Merck KGaA to develop and commercialize a new mass spectrometry-based solution for the pharmaceutical industry. The partnership aims to improve drug discovery and development processes through advanced mass spectrometry techniques (Agilent Technologies Press Release, 2024).
• In May 2024, Bruker Corporation, a leading mass spectrometry equipment manufacturer, completed the acquisition of FFT Technologies, a German company specializing in Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. The acquisition strengthened Bruker's position in the high-end market and expanded its FT-ICR product portfolio (Bruker Corporation Press Release, 2024).
• In February 2025, the European Union approved the new European Mass Spectrometry Research Infrastructure, which will provide open access to advanced mass spectrometry facilities for researchers across Europe. This initiative is expected to boost research and innovation in various sectors, including healthcare, food, and environmental sciences (European Commission Press Release, 2025).

Dive into Technavio's robust research methodology, blending expert interviews, extensive data synthesis, and validated models for unparalleled Mass Spectrometry Market insights. See full methodology.

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Research Analyst Overview

• The market is a dynamic and evolving landscape, driven by advancements in analytical techniques and the growing demand for comprehensive molecular analysis. One of the key areas of focus is lipidomics analysis, which utilizes high-resolution mass spectrometry to identify and quantify lipids in complex biological samples. Data independent acquisition, a versatile mass spectrometry technique, plays a pivotal role in this field. It allows for the simultaneous acquisition of multiple precursor ions, enabling a more comprehensive understanding of complex lipid mixtures. Neutral loss scanning, another technique, facilitates the identification of specific lipid classes by detecting the loss of neutral molecules during fragmentation.
• Peptide mass fingerprinting and protein identification software are essential tools in proteomics workflows, while quadrupole time-of-flight and orbitrap mass analyzers offer high mass resolution and accuracy for precise identification of proteins and metabolites. Ion mobility spectrometry further enhances the capabilities of mass spectrometry by separating ions based on their shape and size, leading to improved resolution and increased sensitivity. Techniques such as selected reaction monitoring, multiple reaction monitoring, and product ion scanning enable quantitative mass spectrometry, offering valuable insights into metabolite profiling and pharmaceutical research. Mass spectrometry imaging provides a spatial dimension to molecular analysis, allowing for the visualization of molecular distributions within complex samples.
• The dynamic range of mass spectrometry is continually expanding, with advancements in mass accuracy and the integration of techniques like gas chromatography-mass spectrometry and tandem mass spectrometry. Mass spectrometry software plays a crucial role in data processing and interpretation, enabling researchers to extract meaningful insights from complex data sets. In conclusion, the market is characterized by ongoing innovation and the integration of various techniques to address the growing demand for comprehensive molecular analysis. From lipidomics to proteomics, mass spectrometry continues to be a powerful tool in the fields of biology, pharmaceuticals, and materials science.

What are the Key Data Covered in this Mass Spectrometry Market Research and Growth Report?

• What is the expected growth of the Mass Spectrometry Market between 2025 and 2029?

  • USD 4.28 billion, at a CAGR of 13.2%

• What segmentation does the market report cover?

  • The report segmented by End-user (P and B industries, Chemical and petrochemical industries, and Others), Product (Instruments and Consumables and services), Technology (QLC-MS, GC-MS, FT-MS, ToFMS, and Others), and Geography (North America, Europe, Asia, and Rest of World (ROW))

• Which regions are analyzed in the report?

  • North America, Europe, Asia, and Rest of World (ROW)

• What are the key growth drivers and market challenges?

  • Increase in use of hyphenated technology, High cost of mass spectrometry instruments

• Who are the major players in the Mass Spectrometry Market?

  • Key Companies 908 Devices Inc., ABB Ltd., Agilent Technologies Inc., Bruker Corp., Endress Hauser Group Services AG, JEOL Ltd., Kore Technology Ltd., LECO Corp., MOBILion Systems Inc., Perkin Elmer Inc., Rigaku Corp., Shimadzu Corp., Teledyne Technologies Inc., Thermo Fisher Scientific Inc., and Waters Corp.

Market Research Insights

• The market encompasses a range of applications, including drug discovery, statistical analysis, pathway analysis, untargeted metabolomics, targeted proteomics, and various techniques such as isobaric labeling, protein structure determination, and MS instrument calibration. Two significant aspects of this market are the increasing adoption of advanced technologies and the expanding scope of applications. For instance, the use of mass calibration, peak alignment, and data normalization in MS data processing has facilitated more accurate and reliable results. Moreover, the integration of fragmentation patterns, spectral matching, peptide sequencing, and mass calibration in peptide identification has streamlined protein quantification and post-translational modification analysis.
• These advancements have led to the market's growth. Furthermore, the application of mass spectrometry in clinical proteomics, environmental proteomics, and food safety testing underscores its versatility and importance in various industries.

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