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The in-vitro and in-vivo micro electrode array market size is forecast to increase by USD 7 million, at a CAGR of 4.3% between 2023 and 2028. The market is witnessing significant growth due to the extensive use of MEAs in neuroscience research. Multiwell and Single well MEAs are gaining popularity in the research community for their ability to record electrical activity from large populations of neurons. Moreover, the potential application of in-vitro and in-vivo MEAs in cancer tissue detection is a promising trend, as these arrays can provide real-time information on cellular responses to various stimuli. However, there are limitations to MEAs, including the need for specialized equipment and the difficulty in maintaining stable recordings over long periods. Another challenge is the high cost of CMOS-based MEAs, which can limit their widespread adoption. Precision Instruments and other key players in the market are investing in research and development to address these challenges and expand the applications of MEAs in various fields, including neurological disorders and drug discovery.
The market is witnessing significant growth due to its increasing application in various fields, including neuroscience research and neurotechnology. Micro electrode arrays (MEAs) are innovative tools used for measuring neural activity and electrical signals from living cells or tissues. These arrays are essential in understanding brain function, neurological disorders, and developing diagnostic and therapeutic solutions. Micro electrode arrays come in different configurations, such as multiwell MEAs and single well MEAs. MEAs consist of an array of microelectrodes, typically made of silicon or other materials, which are used to record electrical activity from cells or tissues. The MEA technology is evolving, with the latest advancements in CMOS-based MEAs, which offer higher resolution, improved sensitivity, and lower noise levels. Neuroscience research is one of the primary applications of in-vitro micro electrode arrays. Researchers use these arrays to study neural activity in various organisms, including mammals, to understand brain function and the underlying mechanisms of neurological disorders. MEAs are also used in neuroengineering to develop neural prostheses and brain-machine interfaces, which can help restore function in individuals with neurological conditions. Another significant application of in-vitro micro electrode arrays is in cancer tissue detection. MEAs can be used to detect electrical signals from cancer cells, which can help in early diagnosis and monitoring of cancer progression. MEAs can also be used to study the electrical properties of cancer cells, which can provide valuable information for developing targeted therapies. The biotech and pharmaceutical industries are also adopting in-vitro micro electrode arrays for research and development purposes. MEAs are used to study the effects of drugs on neural activity and to optimize drug delivery systems.
MEAs can also be used to study the electrical properties of cells, which can help in the development of new therapeutic solutions. Advancements in 3D nanoparticle printing technology are also driving the growth of the in-vitro micro electrode array market. This technology enables the fabrication of complex MEA structures with high precision and accuracy, which can improve the performance of MEAs and expand their applications. In-vitro micro electrode arrays are essential tools for measuring neural activity and electrical signals from living cells or tissues. These arrays have significant applications in neuroscience research, neurotechnology, cancer tissue detection, and the biotech and pharmaceutical industries. With continuous advancements in technology, the in-vitro micro electrode array market is expected to grow further and provide valuable insights into the electrical properties of cells and tissues, leading to the development of new diagnostic and therapeutic solutions. In conclusion, the in-vitro micro electrode array market is a dynamic and growing field, with significant applications in neuroscience research, neurotechnology, cancer tissue detection, and the biotech and pharmaceutical industries. MEAs are essential tools for measuring neural activity and electrical signals from living cells or tissues, and advancements in technology are expanding their applications and improving their performance. The future of the in-vitro micro electrode array market looks promising, with the potential to provide valuable insights into the electrical properties of cells and tissues, leading to the development of new diagnostic and therapeutic solutions.
The market research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD million" for the period 2024-2028, as well as historical data from 2018 - 2022 for the following segments.
The pharmaceutical companies segment is estimated to witness significant growth during the forecast period. In the realm of neuroscience research, In-Vitro and In-Vivo Micro Electrode Arrays have emerged as essential diagnostic and therapeutic solutions for investigating neural activity and brain function. Pharmaceutical and biotechnology companies, along with Contract Research Organizations (CROs), employ these advanced technologies to study drug candidates and understand the intricacies of electrical signals generated by neurons. CROs offer cost-effective research solutions, providing access to extensive equipment and laboratory facilities, enabling tasks ranging from fundamental research to late-stage development.
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The pharmaceutical companies and CROs segment was valued at USD 14.70 million in 2018. Activities encompass genetic engineering, safety and efficacy tests using animal models, hit exploration and lead optimization, assay development, target validation, and clinical trials involving human subjects. Some pharmaceutical and biotechnology firms specializing in neurodegenerative disorders and other brain conditions either acquire smaller CROs or conduct neuroscience research in-house to maintain control over the research process.
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North America is estimated to contribute 58% to the growth of the global market during the forecast period. Technavio's analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period. The In-Vitro and In-Vivo Micro Electrode Array (MEA) market has witnessed significant growth due to the increasing focus on neuroscience research and the development of advanced technologies for improving biocompatibility and signal quality. High-density electrodes are a crucial component of MEAs, enabling the recording of neural activity with high precision. In North America, the market holds a substantial share, driven by a large population suffering from neurological and psychiatric disorders, such as Alzheimer's disease, Parkinson's disease, depression, sleep disorders, epilepsy, stroke, traumatic brain injury, and migraine. Government agencies, including the National Institutes of Health (NIH), invest heavily in research projects to better understand neuroscience and discover treatments for brain disorders. For instance, the NIH's BRAIN initiative aims to map the human brain and develop new technologies to study brain function. The adoption of wireless recording technologies and the integration of MEAs with Brain-Computer Interfaces (BCIs) and personalized medicine further fuel the market growth. Drug candidates under development for various neurological disorders are also expected to boost the demand for MEAs in the pharmaceutical industry.
Our researchers analyzed the data with 2023 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
The extensive use of MEAs in neuroscience research is notably driving market growth. In-vivo Micro Electrode Arrays (MEAs) are a significant tool in the field of neuroscience research, particularly for investigating neuronal pathology, physiology, and circuit connectivity under both laboratory and living organism conditions. MEAs have shown promising results in the treatment of neurological disorders, such as Parkinson's disease, through techniques like deep brain stimulation. Moreover, these arrays offer valuable insights into complex procedures, such as memory formation and perception, and hold therapeutic potential for various conditions, including depression, epilepsy, and obsessive-compulsive disorder.
MEAs are extensively utilized for understanding neuronal processing, information encoding, communication, and propagation in neuronal cultures, retina explants, and brain slices. In cancer research, MEAs based on Complementary Metal-Oxide-Semiconductor (CMOS) technology have demonstrated potential for cancer tissue detection and monitoring tumor growth. Thus, such factors are driving the growth of the market during the forecast period.
The potential application of in-vitro and in-vivo MEA in cancer tissue detection is the key trend in the market. In the realm of biomedical research, the detection and understanding of neurological disorders and cancer continue to pose significant challenges. To address these complexities, researchers are exploring innovative technologies, including Micro Electrode Arrays (MEAs), for the investigation of electrical impedance and activity in cell and tissue cultures. MEAs come in various formats, such as Multiwell and Single well, and the latest advancements include CMOS-based MEAs from Precision Instruments.
The integration of micro-needle arrays with MEA technology is a promising development, as it allows for the non-invasive monitoring of electrical impedance in cancerous tissues. This approach offers the potential to identify distinct electrical signatures of various cancer cells, contributing to earlier and more accurate diagnoses. By studying the electrical activity in cell and tissue cultures, researchers can gain valuable insights into the underlying mechanisms of these diseases, ultimately leading to the development of more effective treatments. Thus, such trends will shape the growth of the market during the forecast period.
Limitations of MEAs is the major challenge that affects the growth of the market. In-Vitro and In-Vivo Micro Electrode Arrays (MEAs) have gained significant attention in various research fields, including pharmaceutical and biotech industries, Neurostimulation devices, and research institutions such as Contract Research Organizations (CROs) and government research labs. MEAs, particularly 3D nanoparticle printed in vitro MEAs, offer advantages like high-density electrode arrays and real-time monitoring of neural activity. However, they face limitations in terms of spatial resolution and complex signal transmission compared to dynamic clamp and patch clamp systems.
Moreover, the implantation of MEAs, especially for chronic use, elicits various biological responses, including a decrease in functional electrodes, glial scarring, and neuronal cell loss. These responses are influenced by factors like MEA shank sizes, inter-shank distances, and MEA material composition, as well as the duration of insertion. Despite these challenges, the potential applications of MEAs in drug discovery, neuroscience research, and neuroprosthetics make them an essential tool in the scientific community. Hence, the above factors will impede the growth of the market during the forecast period
The market forecasting report includes the adoption lifecycle of the market, covering from the innovator's stage to the laggard's stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.
Customer Landscape
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.
3Brain AG - The company offers in-vitro and in-vivo micro electrode array solutions such as CorePlate Technology. It relies on an outstanding chip unique in the MEA world which features thousands of extracellular electrodes per well that can be recorded simultaneously or used to release an electrical stimulation.
The market research and growth report also includes detailed analyses of the competitive landscape of the market and information about key companies, including:
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
In-vivo micro electrode arrays have gained significant attention in the scientific community due to their potential applications in various fields, including neurological disorders, cancer tissue detection, and neurostimulation devices. These arrays, also known as micro electrode arrays (MEAs), are used to measure electrical signals from neurons and neural networks in real-time. MEAs are available in different configurations, such as multiwell and single well arrays, and can be fabricated using CMOS-based technologies. In vitro MEAs are commonly used for drug development, disease modeling, and diagnostic solutions, while in vivo MEAs are employed in clinical settings for brain-computer interfaces, deep brain stimulation, and neuroprosthetics. Neurological disorders, such as epilepsy and Parkinson's disease, are among the primary applications of MEAs. These arrays enable researchers to study neural activity and brain function in detail, leading to a better understanding of brain-related disorders. Cancer tissue detection is another promising application of MEAs, with researchers exploring the use of graphene-based electrodes and flexible electrodes for detecting electrical signals from cancer cells.
The high-density electrodes in MEAs offer improved signal quality and biocompatibility, making them suitable for personalized medicine and drug candidates screening. The fabrication of MEAs involves advanced microfabrication techniques, including photolithography and 3D printing, to create precise and reliable electrodes. The development of wireless recording technologies and the integration of MEAs with neuroprosthetics and brain-computer interfaces are expected to drive further growth in this market. Pharmaceutical and biotech companies, contract research organizations, and government research labs are among the key end-users of MEAs, driving the demand for these diagnostic and therapeutic solutions. The market for MEAs is expected to grow significantly due to the increasing focus on precision instruments and the development of new applications in neuroengineering, synaptic connections, and deep brain stimulation.
Market Scope |
|
Report Coverage |
Details |
Page number |
155 |
Base year |
2023 |
Historic period |
2018 - 2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 4.3% |
Market Growth 2024-2028 |
USD 7 million |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
4.0 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 58% |
Key countries |
US, UK, Germany, France, and Japan |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
3Brain AG, Alpha Omega Engineering Ltd., Axion BioSystems Inc., Blackrock Microsystems Inc., Cambridge NeuroTech, FHC Inc., Harvard Bioscience Inc., IMEC Inc., Innovative Neurophysiology Inc., MaxWell Biosystems AG, Microprobes for Life Science, MICRUX FLUIDIC S.L., NeuroNexus Technologies Inc., NMI Technologie Transfer GmbH, Plexon Inc., Ripple Neuro, Screen Holdings Co. Ltd, SpikeGadgets, Tucker Davis Technologies, and World Precision Instruments |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for market forecast period |
Customization purview |
If our market report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by End-user
7 Market Segmentation by Type
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Opportunity/Restraints
11 Competitive Landscape
12 Competitive Analysis
13 Appendix
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