Oligonucleotide Synthesis Market Size 2025-2029
The oligonucleotide synthesis market size is forecast to increase by USD 4.75 billion at a CAGR of 17.4% between 2024 and 2029.
- The market is experiencing significant growth, driven by the increasing shift towards RNA-based therapeutics. This trend is fueled by the advancements in RNA technology and the potential of RNA therapeutics to treat various diseases, including genetic disorders and cancer. Another trend transforming the market is the integration of artificial intelligence (AI) and automation in oligonucleotide synthesis. This technology enhances efficiency, reduces errors, and lowers production costs.
- However, regulatory issues associated with oligonucleotide therapeutics remain a challenge. Stringent regulatory requirements and lengthy approval processes can hinder market growth. Additionally, ensuring the safety and efficacy of these therapeutics is crucial to gaining regulatory approval and market acceptance. Agilent Technologies, a leading company, offers oligonucleotide synthesis products such as SurePrint HiFi for the production of completely custom oligo pools in rapid turnaround times.
What will the size of the market be during the forecast period?

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1 Executive Summary
- 1.1 Market overview
- Executive Summary - Chart on Market Overview
- Executive Summary - Data Table on Market Overview
- Executive Summary - Chart on Global Market Characteristics
- Executive Summary - Chart on Market by Geography
- Executive Summary - Chart on Market Segmentation by Application
- Executive Summary - Chart on Market Segmentation by End-user
- Executive Summary - Chart on Incremental Growth
- Executive Summary - Data Table on Incremental Growth
- Executive Summary - Chart on Company Market Positioning
2 Technavio Analysis
- 2.1 Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria
- Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria
- 2.2 Criticality of inputs and Factors of differentiation
- Overview on criticality of inputs and factors of differentiation
- 2.3 Factors of disruption
- Overview on factors of disruption
- 2.4 Impact of drivers and challenges
- Impact of drivers and challenges in 2024 and 2029
3 Market Landscape
- 3.1 Market ecosystem
- Parent Market
- Data Table on - Parent Market
- 3.2 Market characteristics
- Market characteristics analysis
4 Market Sizing
- 4.1 Market definition
- Offerings of companies included in the market definition
- 4.2 Market segment analysis
- 4.4 Market outlook: Forecast for 2024-2029
- Chart on Global - Market size and forecast 2024-2029 ($ million)
- Data Table on Global - Market size and forecast 2024-2029 ($ million)
- Chart on Global Market: Year-over-year growth 2024-2029 (%)
- Data Table on Global Market: Year-over-year growth 2024-2029 (%)
5 Historic Market Size
- 5.1 Global Oligonucleotide Synthesis Market 2019 - 2023
- Historic Market Size - Data Table on Global Oligonucleotide Synthesis Market 2019 - 2023 ($ million)
- 5.2 Application segment analysis 2019 - 2023
- Historic Market Size - Application Segment 2019 - 2023 ($ million)
- 5.3 End-user segment analysis 2019 - 2023
- Historic Market Size - End-user Segment 2019 - 2023 ($ million)
- 5.4 Geography segment analysis 2019 - 2023
- Historic Market Size - Geography Segment 2019 - 2023 ($ million)
- 5.5 Country segment analysis 2019 - 2023
- Historic Market Size - Country Segment 2019 - 2023 ($ million)
6 Qualitative Analysis
- 6.1 The AI impact on global oligonucleotide synthesis market
7 Five Forces Analysis
- 7.1 Five forces summary
- Five forces analysis - Comparison between 2024 and 2029
- 7.2 Bargaining power of buyers
- Bargaining power of buyers - Impact of key factors 2024 and 2029
- 7.3 Bargaining power of suppliers
- Bargaining power of suppliers - Impact of key factors in 2024 and 2029
- 7.4 Threat of new entrants
- Threat of new entrants - Impact of key factors in 2024 and 2029
- 7.5 Threat of substitutes
- Threat of substitutes - Impact of key factors in 2024 and 2029
- 7.6 Threat of rivalry
- Threat of rivalry - Impact of key factors in 2024 and 2029
- 7.7 Market condition
- Chart on Market condition - Five forces 2024 and 2029
8 Market Segmentation by Application
- 8.1 Market segments
- Chart on Application - Market share 2024-2029 (%)
- Data Table on Application - Market share 2024-2029 (%)
- 8.2 Comparison by Application
- Chart on Comparison by Application
- Data Table on Comparison by Application
- 8.3 PCR primers - Market size and forecast 2024-2029
- Chart on PCR primers - Market size and forecast 2024-2029 ($ million)
- Data Table on PCR primers - Market size and forecast 2024-2029 ($ million)
- Chart on PCR primers - Year-over-year growth 2024-2029 (%)
- Data Table on PCR primers - Year-over-year growth 2024-2029 (%)
- 8.4 PCR assays and panels - Market size and forecast 2024-2029
- Chart on PCR assays and panels - Market size and forecast 2024-2029 ($ million)
- Data Table on PCR assays and panels - Market size and forecast 2024-2029 ($ million)
- Chart on PCR assays and panels - Year-over-year growth 2024-2029 (%)
- Data Table on PCR assays and panels - Year-over-year growth 2024-2029 (%)
- 8.5 DNA microarrays - Market size and forecast 2024-2029
- Chart on DNA microarrays - Market size and forecast 2024-2029 ($ million)
- Data Table on DNA microarrays - Market size and forecast 2024-2029 ($ million)
- Chart on DNA microarrays - Year-over-year growth 2024-2029 (%)
- Data Table on DNA microarrays - Year-over-year growth 2024-2029 (%)
- 8.6 Fluorescence in situ hybridization - Market size and forecast 2024-2029
- Chart on Fluorescence in situ hybridization - Market size and forecast 2024-2029 ($ million)
- Data Table on Fluorescence in situ hybridization - Market size and forecast 2024-2029 ($ million)
- Chart on Fluorescence in situ hybridization - Year-over-year growth 2024-2029 (%)
- Data Table on Fluorescence in situ hybridization - Year-over-year growth 2024-2029 (%)
- 8.7 Others - Market size and forecast 2024-2029
- Chart on Others - Market size and forecast 2024-2029 ($ million)
- Data Table on Others - Market size and forecast 2024-2029 ($ million)
- Chart on Others - Year-over-year growth 2024-2029 (%)
- Data Table on Others - Year-over-year growth 2024-2029 (%)
- 8.8 Market opportunity by Application
- Market opportunity by Application ($ million)
- Data Table on Market opportunity by Application ($ million)
9 Market Segmentation by End-user
- 9.1 Market segments
- Chart on End-user - Market share 2024-2029 (%)
- Data Table on End-user - Market share 2024-2029 (%)
- 9.2 Comparison by End-user
- Chart on Comparison by End-user
- Data Table on Comparison by End-user
- 9.3 Pharmaceutical and biotechnology companies - Market size and forecast 2024-2029
- Chart on Pharmaceutical and biotechnology companies - Market size and forecast 2024-2029 ($ million)
- Data Table on Pharmaceutical and biotechnology companies - Market size and forecast 2024-2029 ($ million)
- Chart on Pharmaceutical and biotechnology companies - Year-over-year growth 2024-2029 (%)
- Data Table on Pharmaceutical and biotechnology companies - Year-over-year growth 2024-2029 (%)
- 9.4 Research and academic institutes - Market size and forecast 2024-2029
- Chart on Research and academic institutes - Market size and forecast 2024-2029 ($ million)
- Data Table on Research and academic institutes - Market size and forecast 2024-2029 ($ million)
- Chart on Research and academic institutes - Year-over-year growth 2024-2029 (%)
- Data Table on Research and academic institutes - Year-over-year growth 2024-2029 (%)
- 9.5 Diagnostic laboratories - Market size and forecast 2024-2029
- Chart on Diagnostic laboratories - Market size and forecast 2024-2029 ($ million)
- Data Table on Diagnostic laboratories - Market size and forecast 2024-2029 ($ million)
- Chart on Diagnostic laboratories - Year-over-year growth 2024-2029 (%)
- Data Table on Diagnostic laboratories - Year-over-year growth 2024-2029 (%)
- 9.6 Hospitals - Market size and forecast 2024-2029
- Chart on Hospitals - Market size and forecast 2024-2029 ($ million)
- Data Table on Hospitals - Market size and forecast 2024-2029 ($ million)
- Chart on Hospitals - Year-over-year growth 2024-2029 (%)
- Data Table on Hospitals - Year-over-year growth 2024-2029 (%)
- 9.7 Market opportunity by End-user
- Market opportunity by End-user ($ million)
- Data Table on Market opportunity by End-user ($ million)
10 Customer Landscape
- 10.1 Customer landscape overview
- Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria
11 Geographic Landscape
- 11.1 Geographic segmentation
- Chart on Market share by geography 2024-2029 (%)
- Data Table on Market share by geography 2024-2029 (%)
- 11.2 Geographic comparison
- Chart on Geographic comparison
- Data Table on Geographic comparison
- 11.3 North America - Market size and forecast 2024-2029
- Chart on North America - Market size and forecast 2024-2029 ($ million)
- Data Table on North America - Market size and forecast 2024-2029 ($ million)
- Chart on North America - Year-over-year growth 2024-2029 (%)
- Data Table on North America - Year-over-year growth 2024-2029 (%)
- 11.4 Europe - Market size and forecast 2024-2029
- Chart on Europe - Market size and forecast 2024-2029 ($ million)
- Data Table on Europe - Market size and forecast 2024-2029 ($ million)
- Chart on Europe - Year-over-year growth 2024-2029 (%)
- Data Table on Europe - Year-over-year growth 2024-2029 (%)
- 11.5 Asia - Market size and forecast 2024-2029
- Chart on Asia - Market size and forecast 2024-2029 ($ million)
- Data Table on Asia - Market size and forecast 2024-2029 ($ million)
- Chart on Asia - Year-over-year growth 2024-2029 (%)
- Data Table on Asia - Year-over-year growth 2024-2029 (%)
- 11.6 Rest of World (ROW) - Market size and forecast 2024-2029
- Chart on Rest of World (ROW) - Market size and forecast 2024-2029 ($ million)
- Data Table on Rest of World (ROW) - Market size and forecast 2024-2029 ($ million)
- Chart on Rest of World (ROW) - Year-over-year growth 2024-2029 (%)
- Data Table on Rest of World (ROW) - Year-over-year growth 2024-2029 (%)
- 11.7 US - Market size and forecast 2024-2029
- Chart on US - Market size and forecast 2024-2029 ($ million)
- Data Table on US - Market size and forecast 2024-2029 ($ million)
- Chart on US - Year-over-year growth 2024-2029 (%)
- Data Table on US - Year-over-year growth 2024-2029 (%)
- 11.8 China - Market size and forecast 2024-2029
- Chart on China - Market size and forecast 2024-2029 ($ million)
- Data Table on China - Market size and forecast 2024-2029 ($ million)
- Chart on China - Year-over-year growth 2024-2029 (%)
- Data Table on China - Year-over-year growth 2024-2029 (%)
- 11.9 Germany - Market size and forecast 2024-2029
- Chart on Germany - Market size and forecast 2024-2029 ($ million)
- Data Table on Germany - Market size and forecast 2024-2029 ($ million)
- Chart on Germany - Year-over-year growth 2024-2029 (%)
- Data Table on Germany - Year-over-year growth 2024-2029 (%)
- 11.10 Canada - Market size and forecast 2024-2029
- Chart on Canada - Market size and forecast 2024-2029 ($ million)
- Data Table on Canada - Market size and forecast 2024-2029 ($ million)
- Chart on Canada - Year-over-year growth 2024-2029 (%)
- Data Table on Canada - Year-over-year growth 2024-2029 (%)
- 11.11 UK - Market size and forecast 2024-2029
- Chart on UK - Market size and forecast 2024-2029 ($ million)
- Data Table on UK - Market size and forecast 2024-2029 ($ million)
- Chart on UK - Year-over-year growth 2024-2029 (%)
- Data Table on UK - Year-over-year growth 2024-2029 (%)
- 11.12 Japan - Market size and forecast 2024-2029
- Chart on Japan - Market size and forecast 2024-2029 ($ million)
- Data Table on Japan - Market size and forecast 2024-2029 ($ million)
- Chart on Japan - Year-over-year growth 2024-2029 (%)
- Data Table on Japan - Year-over-year growth 2024-2029 (%)
- 11.13 France - Market size and forecast 2024-2029
- Chart on France - Market size and forecast 2024-2029 ($ million)
- Data Table on France - Market size and forecast 2024-2029 ($ million)
- Chart on France - Year-over-year growth 2024-2029 (%)
- Data Table on France - Year-over-year growth 2024-2029 (%)
- 11.14 Italy - Market size and forecast 2024-2029
- Chart on Italy - Market size and forecast 2024-2029 ($ million)
- Data Table on Italy - Market size and forecast 2024-2029 ($ million)
- Chart on Italy - Year-over-year growth 2024-2029 (%)
- Data Table on Italy - Year-over-year growth 2024-2029 (%)
- 11.15 India - Market size and forecast 2024-2029
- Chart on India - Market size and forecast 2024-2029 ($ million)
- Data Table on India - Market size and forecast 2024-2029 ($ million)
- Chart on India - Year-over-year growth 2024-2029 (%)
- Data Table on India - Year-over-year growth 2024-2029 (%)
- 11.16 South Korea - Market size and forecast 2024-2029
- Chart on South Korea - Market size and forecast 2024-2029 ($ million)
- Data Table on South Korea - Market size and forecast 2024-2029 ($ million)
- Chart on South Korea - Year-over-year growth 2024-2029 (%)
- Data Table on South Korea - Year-over-year growth 2024-2029 (%)
- 11.17 Market opportunity by geography
- Market opportunity by geography ($ million)
- Data Tables on Market opportunity by geography ($ million)
12 Drivers, Challenges, and Opportunity/Restraints
- 12.3 Impact of drivers and challenges
- Impact of drivers and challenges in 2024 and 2029
- 12.4 Market opportunities/restraints
13 Competitive Landscape
- 13.2 Competitive Landscape
- Overview on criticality of inputs and factors of differentiation
- 13.3 Landscape disruption
- Overview on factors of disruption
- 13.4 Industry risks
- Impact of key risks on business
14 Competitive Analysis
- 14.2 Company ranking index
- 14.3 Market positioning of companies
- Matrix on companies position and classification
- 14.4 Agilent Technologies Inc.
- Agilent Technologies Inc. - Overview
- Agilent Technologies Inc. - Business segments
- Agilent Technologies Inc. - Key news
- Agilent Technologies Inc. - Key offerings
- Agilent Technologies Inc. - Segment focus
- SWOT
- 14.5 Ansa Biotechnologies
- Ansa Biotechnologies - Overview
- Ansa Biotechnologies - Product / Service
- Ansa Biotechnologies - Key offerings
- SWOT
- 14.6 Biogen Inc.
- Biogen Inc. - Overview
- Biogen Inc. - Product / Service
- Biogen Inc. - Key news
- Biogen Inc. - Key offerings
- SWOT
- 14.7 Biotage AB
- Biotage AB - Overview
- Biotage AB - Product / Service
- Biotage AB - Key offerings
- SWOT
- 14.8 Danaher Corp.
- Danaher Corp. - Overview
- Danaher Corp. - Business segments
- Danaher Corp. - Key news
- Danaher Corp. - Key offerings
- Danaher Corp. - Segment focus
- SWOT
- 14.9 General Electric Co.
- General Electric Co. - Overview
- General Electric Co. - Business segments
- General Electric Co. - Key news
- General Electric Co. - Key offerings
- General Electric Co. - Segment focus
- SWOT
- 14.10 Kaneka Corp.
- Kaneka Corp. - Overview
- Kaneka Corp. - Business segments
- Kaneka Corp. - Key news
- Kaneka Corp. - Key offerings
- Kaneka Corp. - Segment focus
- SWOT
- 14.11 LGC Science Group Holdings Ltd.
- LGC Science Group Holdings Ltd. - Overview
- LGC Science Group Holdings Ltd. - Product / Service
- LGC Science Group Holdings Ltd. - Key offerings
- SWOT
- 14.12 Merck KGaA
- Merck KGaA - Overview
- Merck KGaA - Business segments
- Merck KGaA - Key news
- Merck KGaA - Key offerings
- Merck KGaA - Segment focus
- SWOT
- 14.13 Mettler Toledo International Inc.
- Mettler Toledo International Inc. - Overview
- Mettler Toledo International Inc. - Business segments
- Mettler Toledo International Inc. - Key news
- Mettler Toledo International Inc. - Key offerings
- Mettler Toledo International Inc. - Segment focus
- SWOT
- 14.14 QIAGEN N.V.
- QIAGEN N.V. - Overview
- QIAGEN N.V. - Product / Service
- QIAGEN N.V. - Key news
- QIAGEN N.V. - Key offerings
- SWOT
- 14.15 Sarepta Therapeutics Inc.
- Sarepta Therapeutics Inc. - Overview
- Sarepta Therapeutics Inc. - Product / Service
- Sarepta Therapeutics Inc. - Key offerings
- SWOT
- 14.16 Synbio Technologies LLC
- Synbio Technologies LLC - Overview
- Synbio Technologies LLC - Product / Service
- Synbio Technologies LLC - Key offerings
- SWOT
- 14.17 Syngene International Ltd.
- Syngene International Ltd. - Overview
- Syngene International Ltd. - Product / Service
- Syngene International Ltd. - Key offerings
- SWOT
- 14.18 Thermo Fisher Scientific Inc.
- Thermo Fisher Scientific Inc. - Overview
- Thermo Fisher Scientific Inc. - Business segments
- Thermo Fisher Scientific Inc. - Key news
- Thermo Fisher Scientific Inc. - Key offerings
- Thermo Fisher Scientific Inc. - Segment focus
- SWOT
15 Appendix
- 15.2 Inclusions and exclusions checklist
- Inclusions checklist
- Exclusions checklist
- 15.3 Currency conversion rates for US$
- Currency conversion rates for US$
- 15.4 Research methodology
- 15.7 Validation techniques employed for market sizing
- Validation techniques employed for market sizing
- 15.9 360 degree market analysis
- 360 degree market analysis
- 15.10 List of abbreviations
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
- Manufacturers and suppliers
- Channel partners
- Industry experts
- Strategic decision makers
Secondary sources
- Industry journals and periodicals
- Government data
- Financial reports of key industry players
- Historical data
- Press releases

DATA ANALYSIS
Data Synthesis
- Collation of data
- Estimation of key figures
- Analysis of derived insights
Data Validation
- Triangulation with data models
- Reference against proprietary databases
- Corroboration with industry experts

REPORT WRITING
Qualitative
- Market drivers
- Market challenges
- Market trends
- Five forces analysis
Quantitative
- Market size and forecast
- Market segmentation
- Geographical insights
- Competitive landscape