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The opioid rescue products market size is forecast to increase by USD 1.69 billion, at a CAGR of 11.6% between 2023 and 2028. The market is experiencing significant growth due to the escalating opioid overdose crisis in the US. According to the National Institute on Drug Abuse, over 130 Americans die daily from an opioid overdose. In response, the opioid industry is focusing on the development and approval of new drugs to address this public health concern. For instance, sublingual tablets and transdermal patches are gaining popularity as they offer quicker relief and improved treatment access for patients suffering from opioid overdoses. However, challenges persist, including the presence of counterfeit drugs and the management of comorbid illnesses such as constipation, which are common in opioid users. The approval of new drugs and the continued innovation in delivery systems will be crucial in addressing these challenges and reducing opioid-related deaths.
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The market research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD billion" for the period 2024-2028, as well as historical data from 2018 - 2022 for the following segments.
The offline segment is estimated to witness significant growth during the forecast period. Opioid rescue products, such as naloxone and naltrexone, play a crucial role in reversing the effects of opioid overdoses and treating opioid addiction. Pharmacies serve as essential distribution channels for these medications, making them easily accessible to the public. Prescriptions and, in certain cases, over-the-counter sales are options for obtaining these life-saving drugs.
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The offline segment was valued at USD 896.70 million in 2018. Major pharmacy chains significantly contribute to making opioid rescue products readily available. First responders, including paramedics, police officers, emergency medical technicians, and non-emergency medical personnel, are increasingly utilizing opioid rescue products. These professionals are often the first on the scene during an opioid overdose and can administer immediate intervention, which is vital in preventing fatalities. Non-governmental organizations also play a significant role in increasing awareness and providing training on the use of opioid rescue products to first responders and the general public.
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North America is estimated to contribute 46% to the growth of the global market during the forecast period. Technavio's analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period. The opioid crisis is a major public health concern in North America, affecting both the United States and Canada. In the United States, during the 12 months ending in February 2023, over 105,000 reported opioid overdoses occurred, primarily due to synthetic opioids like illicit fentanyl. This startling figure highlights the importance of having effective opioid rescue products available to counteract the potentially fatal consequences of opioid overdoses. In Canada, the opioid overdose crisis continues to pose a significant threat to individuals, families, and communities. This crisis is considered one of the most severe public health crises in the country's recent history. Between January 2016 and June 2022, there were approximately 32,600 apparent opioid toxicity deaths. Opioid overdoses can lead to respiratory depression and psychological problems, making it crucial to have accessible and efficient opioid rescue products.
Opioid rescue products, such as naloxone and buprenorphine, play a vital role in reversing opioid overdoses. These medications can help restore normal breathing and prevent further harm. The ongoing opioid crisis necessitates the continuous development and availability of these essential treatments. In conclusion, the opioid crisis is a pressing issue in North America, with the US and Canada experiencing high numbers of opioid overdoses and fatalities. Effective opioid rescue products, like naloxone and buprenorphine, are essential in mitigating the devastating effects of opioid overdoses. It is crucial to ensure these treatments are accessible and readily available to those in need.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.
Alkermes Public Ltd. Co. - The company provides opioid rescue products such as Vivitrol.
Technavio provides the ranking index for the top 16 companies along with insights on the market positioning of:
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Market structure |
Fragmented |
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YoY growth 2023-2024 |
11.0 |
The market continues to be a significant public health concern, with thousands of lives lost each year due to accidental overdoses. Opioid overdose is a serious condition that requires immediate medical attention. It can occur when an individual consumes an excessive amount of opioids, leading to respiratory depression and potentially death. Opioid overdose symptoms include but are not limited to, slowed breathing, confusion, unconsciousness, and pinpoint pupils. In response to this crisis, various opioid overdose medications and resources have emerged to help mitigate the risks associated with opioid use and provide care for those affected. Opioid overdose response involves several key steps, including recognition of symptoms, administration of opioid overdose reversal medication, and providing appropriate care and support. Opioid overdose reversal medications, such as naloxone, are essential tools in the opioid overdose response arsenal. These medications work by binding to opioid receptors in the brain and reversing the effects of opioids, allowing the individual to breathe normally again. Opioid overdose prevention and education are crucial components of addressing the opioid crisis. Providing resources and information on opioid misuse prevention, harm reduction, and addiction treatment can help reduce the number of opioid overdoses and save lives. Opioid crisis solutions also include the development of opioid alternatives, such as non-opioid pain management options and opioid regulation through legislation and policy. Buprenorphine therapy, including buprenorphine patches, is a valuable tool in the treatment of opioid addiction. This medication, which is a partial opioid agonist, can help reduce cravings and withdrawal symptoms, making it an effective option for those seeking to recover from opioid addiction.
Opioid treatment centers and support groups also play a vital role in providing care and resources for those struggling with opioid addiction. Opioid regulation and legislation are essential in addressing the opioid crisis. Policymakers and advocacy groups are working to develop and implement regulations and policies aimed at reducing opioid misuse and increasing access to opioid overdose reversal medications and addiction treatment. In addition, the opioid crisis is a complex issue that requires a multi-faceted approach to address. Opioid overdose prevention, education, response, and care are all crucial components of addressing this crisis. Opioid overdose reversal medications, such as naloxone, and opioid alternatives, such as buprenorphine therapy, are essential tools in the fight against opioid overdoses and addiction. Ongoing efforts to develop and implement regulations and policies aimed at reducing opioid misuse and increasing access to treatment will continue to be essential in addressing this crisis. Our researchers analyzed the data with 2023 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
Increasing rates of opioid overdoses is notably driving market growth. The market continues to pose a significant public health concern in the United States, with the National Center for Health Statistics of the Centers for Disease Control and Prevention (CDC) reporting an estimated 107,543 drug overdose deaths in 2023. Opioid rescue products play a crucial role in addressing this issue by providing effective interventions for opioid overdoses. Hospital pharmacies are key providers of these essential medications, which can reverse the effects of opioid overdoses and prevent fatalities.
Opioid rescue products are designed to alleviate symptoms such as abdominal cramps, muscle aches, and diarrhea associated with opioid use disorder. The European Union also faces a concerning trend in overdose mortality, with an estimated 22 deaths per million population aged 15 to 64 years in 2022. Thus, such factors are driving the growth of the market during the forecast period.
Approval of new drugs is the key trend in the market. The market is experiencing notable progress with the introduction of new approvals for life-saving treatments against opioid overdoses in the United States. On August 7, 2024, the U.S. Food and Drug Administration (FDA) granted approval to Zurnai, the first nalmefene hydrochloride auto-injector. This device is intended for emergency treatment of opioid overdoses in adults and pediatric patients aged 12 years and above. The approval of Zurnai represents a significant milestone, offering a convenient, easy-to-use solution for rapid intervention during overdose incidents.
This decision follows the FDA's endorsement of the first nalmefene nasal spray formulation in May 2023. The availability of these new opioid rescue products is crucial, as comorbid illnesses, such as constipation and mental health disorders, can complicate opioid treatment and increase the risk of overdoses. Enhancing treatment access to opioid rescue products is essential to mitigate the ongoing opioid crisis and reduce overdose deaths in the US. Thus, such trends will shape the growth of the market during the forecast period.
The presence of counterfeit drugs is the major challenge that affects the growth of the market. The market faces a significant challenge due to the prevalence of counterfeit drugs. According to the World Health Organization, counterfeit medical products are those that are intentionally misrepresented in terms of identity, composition, or source. These products include not only counterfeit, altered, and stolen items, but also illegally diverted ones. The increasing issue of falsified medical products is fueled by various factors, such as criminal profit motives, insufficient legislation and regulation, and a lack of collaboration among key players. Counterfeit opioid rescue products pose a serious threat to patients worldwide. They can erode trust in healthcare systems and among healthcare professionals, potentially leading to a loss of confidence in the medications available. Some of these counterfeit products may contain incorrect dosages, inappropriate ingredients, or no active ingredients at all. Furthermore, they can cause side effects and respiratory complications, and may even lead to bladder pain.
Suboxone, a commonly used opioid rescue medication, is particularly vulnerable to counterfeiting due to its high demand and value. Formulary coverage and access to legitimate opioid rescue products are crucial in mitigating the risks associated with counterfeit drugs. It is essential for healthcare providers and patients to be aware of the signs of counterfeit medications and to report any suspicious products to the appropriate authorities. Regular testing of medications and strict regulation and enforcement of pharmaceutical supply chains can also help reduce the prevalence of counterfeit opioid rescue products. Hence, the above factors will impede the growth of the market during the forecast period.
The market forecasting report includes the adoption lifecycle of the market research and growth, covering from the innovator's stage to the laggard's stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.
Customer Landscape
Opioid overdose is a life-threatening condition caused by the misuse of opioid-based painkillers and other prescription drugs. Respiratory depression is a common complication of opioid overdose, which can lead to death if not treated promptly. Naloxone is an essential opioid rescue product used to reverse the effects of opioid overdose. It works by binding to the opioid receptors in the body and blocking the effects of the overdosed opioid. Opioid overdose treatment also includes medications like buprenorphine, which is used to manage opioid use disorder and prevent relapse. However, these treatments can have side effects such as abdominal cramps, muscle aches, diarrhea, and psychological problems. Hospital pharmacies play a crucial role in the availability of opioid rescue products. They stock various drug delivery systems, including injections, sublingual tablets, and transdermal patches, to provide timely treatment to patients. However, formulary coverage and access to these treatments can be a challenge for some patients, especially those with comorbid illnesses or addiction.
The market has been under scrutiny due to the rising number of overdose deaths and addiction cases. Non-governmental organizations are working to increase awareness about the risks of opioid use and provide support to those affected by addiction. Opioid treatment options also include naltrexone, which blocks the effects of opioids and can help prevent relapse. Cardiovascular disorders, constipation, vomiting, joint pain, and drug withdrawal are some of the common side effects of long-term opioid use. Opioid treatment is essential for managing chronic pain, cancer, and other medical conditions, but it comes with risks and challenges. The use of opioid-based painkillers should be closely monitored, and patients should be educated about the risks and signs of overdose.
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Market Scope |
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Report Coverage |
Details |
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Page number |
200 |
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Base year |
2023 |
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Historic period |
2018 - 2022 |
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Forecast period |
2024-2028 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 11.6% |
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Market Growth 2024-2028 |
USD 1.69 billion |
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Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
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Performing market contribution |
North America at 46% |
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Key countries |
US, China, Germany, UK, France, Spain, Japan, South Korea, India, and Brazil |
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Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
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Key companies profiled |
Alkermes Public Ltd. Co., Amneal Pharmaceuticals Inc., Catalent Inc., Emergent BioSolutions Inc., F. Hoffmann La Roche Ltd., Fresenius Kabi AG, Hikma Pharmaceuticals Plc, Kyowa Kirin Co. Ltd., Mallinckrodt Plc, Novartis AG, Orexo AB, Pfizer Inc., Purdue Pharma LP, Sun Pharmaceutical Industries Ltd., Teva Pharmaceutical Industries Ltd., and Viatris Inc. |
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Market dynamics |
Parent market analysis, market growth inducers and obstacles, fast-growing and slow-growing segment analysis, AI impact on market trends, COVID-19 impact and recovery analysis and future consumer dynamics, market condition analysis for the market forecast period |
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Customization purview |
If our market report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
1 Executive Summary
2 Technavio Analysis
3 Market Landscape
4 Market Sizing
5 Historic Market Size
6 Qualitative Analysis
7 Five Forces Analysis
8 Market Segmentation by Distribution Channel
9 Market Segmentation by Product Type
10 Customer Landscape
11 Geographic Landscape
12 Drivers, Challenges, and Opportunity/Restraints
13 Competitive Landscape
14 Competitive Analysis
15 Appendix
Research Framework
Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.
INFORMATION SOURCES
Primary sources
Secondary sources
DATA ANALYSIS
Data Synthesis
Data Validation
REPORT WRITING
Qualitative
Quantitative
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