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The Preclinical Isolated Organ Perfusion System Market size is estimated to grow by USD 137.63 million at a CAGR of 4.86% between 2023 and 2028.
The demand for organ transplantation continues to escalate, particularly for the kidney, heart, liver, and lungs. Unhealthy dietary habits, accidents resulting in organ damage, long-term illnesses, sedentary lifestyles, and alcohol consumption are primary contributors to organ failure. This escalating issue has necessitated advanced organ preservation techniques, such as isolated organ perfusion, to facilitate successful transplantation surgeries.
Moreover, the increasing incidence of organ failure has significant implications for cardiovascular therapeutics. Cardiovascular diseases, including heart failure, are a leading cause of organ transplantation. The development and refinement of organ preservation methods are crucial in addressing the growing need for cardiovascular transplants. These advancements not only improve patient outcomes but also contribute to the expansion of the organ transplantation market. The rising demand for organ transplantation, driven by various factors, is positively impacting the market, particularly in the context of cardiovascular therapeutics. The need for advanced organ preservation techniques, such as isolated organ perfusion, is essential in addressing the growing incidence of organ failure and ensuring successful transplantation surgeries.
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It also includes an in-depth analysis of drivers, trends, and challenges. Our report examines historic data from 2018 to 2022, besides analyzing the current market scenario.
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This market report entails segmentation by end-user (Industrial laboratories and CROs and Academic and government research institutes), type (Isolated heart perfusion systems, Isolated abdominal organ perfusion systems, Isolated lung perfusion systems, and Others), and geography (North America, Europe, Asia, and ROW).
Industrial laboratories and CROs
The industrial laboratories and CROs segment is estimated to witness significant growth during the forecast period. This segment is one of the main organizations that are involved in drug discovery, research, design, and development. In addition, these organizations have the infrastructure required to conduct preclinical and clinical studies for testing various drug candidates. The rising investment of pharmaceutical companies in drug discovery and the increase in outsourcing activities to CROs is fuelling the growth of this segment.
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The industrial laboratories and Contract Research Organization (CRO) segment was the largest segment and was valued at USD 264.88 million in 2018. Moreover, pharma and biotech companies are primarily involved in the discovery and development of drugs for a wide array of therapeutic applications. In addition, the increasing prevalence of chronic diseases, such as cardiovascular diseases and respiratory disorders, drives the demand for new drug discovery among these end-users. Furthermore, isolated organ perfusion systems are used to study the pharmacology of new drugs on isolated organs. Hence, such factors are expected to fuel the growth of this segment which in turn will drive the market growth during the forecast period.
The rising prevalence of cardiovascular diseases, technological advances, and the strong presence of key companies offering isolated heart perfusion systems are signficantly contributing to the growth of this segment. In addition, cardiovascular disease is a major cause of morbidity and mortality across the world. Therefore, the risk and prevalence of cardiovascular diseases are likely to increase owing to sedentary lifestyle and the growing elderly population. As a result, it has fueled research activities and drug discovery processes for the development of new drugs for cardiovascular diseases. Hence, isolated heart perfusion systems are used in preclinical research to study the pharmacological response of new cardiovascular drugs on isolated hearts to understand drug toxicity and dosage. Therefore, such factors fuel the growth of this segment which in turn drives the market growth.
Isolated abdominal organ perfusion systems comprise isolated liver perfusion systems and isolated kidney perfusion systems. This segment is mainly designed for pharmacological researchers investigating the liver and kidneys of small animals. In addition, these systems are used for studying the different functions of the kidneys and liver, such as kidney secretory function, renal metabolism, liver malignancies, liver fibrosis, and hepatotoxicity. Several market players in the global isolated organ perfusion system market offer different isolated abdominal organ perfusion systems. For example, ADInstruments offers an isolated perfused rodent liver foundation system, which is used to study rodent liver. Hence, such factors are expected to fuel the growth of this segment which in turn will drive the market growth during the forecast period.
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North America is estimated to contribute 36% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that will shape the market during the forecast period. Factors such as the presence of key vendors, technological advances, increasing funding and research in life science research, and the presence of established pharmaceutical companies and research institutes are significantly contributing to the growth of the market in North America. Some of the key market players include Harvard Bioscience Inc., Radnoti LLC, and Emka Technologies positively impacting the market. In addition, the growing adoption of advanced technologies and products, including isolated organ perfusion systems in preclinical research is fuelling the market growth in the region. Hence, such factors are expected to drive market growth in North America during the forecast period.
In 2020, during the COVID-19 pandemic, the growth of global preclinical isolated organ perfusion system market witnessed significant growth as several pharmaceutical and biopharmaceutical companies boosted their R&D and manufacturing processes to develop and distribute COVID-19 test kits, vaccines, and drugs against the virus in North America. However, in 2021, the initiation of large-scale vaccination drives lifted the lockdown and travel restrictions, which led to an increase in demand. Such factors are expected to drive the market during the forecast period.
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Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about 8 market companies, including:
ADInstruments Pty Ltd: The company offers preclinical isolated organ perfusion systems such as the Isolated Perfused Rodent Liver Foundation System which provides the glassware for perfusing an isolated rodent liver to maintain its hepatic function.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The preclinical isolated organ perfusion system market is experiencing significant growth, driven by several key factors and trends. One of the primary drivers is the increasing prevalence of chronic diseases, such as cancer, cardiovascular diseases, and respiratory diseases, which necessitates the need for new drugs and therapeutic interventions. Isolated organ perfusion systems are essential tools in preclinical research, enabling the study of organ-targeted drug delivery and the physiological effects of new drugs on isolated organs.
Moreover, the market is witnessing notable trends, including the increasing investment in R&D and preclinical research. Pharmaceutical companies are significant end-users of isolated organ perfusion systems, as they are utilized to investigate drug toxicity and the impact of new drug molecules on targeted organs. The rising pharmaceutical R&D investment by key market players is fueling the growth of drug discovery and preclinical research activities. Additionally, the strong pipeline of drugs in various stages of development, including the preclinical stage, coupled with investment in R&D, is expected to drive market growth. Furthermore, advancements in drug discovery informatics are expected to provide new opportunities for market expansion.
The high cost of isolated organ perfusion systems is one of the key challenges hindering the preclinical isolated organ perfusion system market growth. The growing need for isolated organ studies, mainly in preclinical research, has fuelled the adoption of isolated organ perfusion systems. However, the high cost of isolated organ perfusion systems poses a significant threat to the market. In addition, the cost of an isolated organ perfusion system varies, depending on the organ type, brand, and quality, and it ranges from USD30,000 to USD35,000.
Moreover, the price of the product also varies depending on the domestic or international market rates. In addition, the cost of an isolated organ perfusion system increases with the type of organ being studied. For example, some organs may require additional equipment to study their specialized functions, such as a ventilator for isolated perfused lungs. Hence, such factors hinder the market growth during the forecast period.
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The market report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.
Global Preclinical Isolated Organ Perfusion System Market Customer Landscape
The preclinical isolated organ perfusion system market report forecasts market growth by revenue at global, regional & country levels and provides an analysis of the latest trends and growth opportunities from 2018 to 2028.
Preclinical Isolated Organ Perfusion System Market Scope |
|
Report Coverage |
Details |
Page number |
156 |
Base year |
2023 |
Historic period |
2018-2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 4.86% |
Market growth 2024-2028 |
USD 137.63 million |
Market structure |
Concentrated |
YoY growth 2023-2024(%) |
3.8 |
Regional analysis |
North America, Europe, Asia, and the Rest of the World (ROW) |
Performing market contribution |
North America at 36% |
Key countries |
US, Canada, Germany, China, and India |
Competitive landscape |
Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks |
Key companies profiled |
ADInstruments Pty Ltd., ALA Scientific Instruments Inc., emka TECHNOLOGIES, Harvard Bioscience Inc., MDE GmbH, Radnoti LLC, World Precision Instruments, and XVIVO Perfusion AB |
Market dynamics |
Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by End-user
7 Market Segmentation by Type
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Trends
11 Vendor Landscape
12 Vendor Analysis
13 Appendix
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