Anticoagulants Market in the US 2016-2020

  • Published: May 2016
  • Pages: 89
  • SKU: IRTNTR9372

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This market research report presents a detailed segmentation of the anticoagulants market in the US by ROA (oral and injectables), by drug class (heparin, Factor Xa inhibitors, direct thrombin inhibitors, and vitamin K antagonists), and by application (DVT, PE, acute coronary syndrome, AF, hemodialysis, coronary angioplasty, and surgeries). The leading vendors in the market include Boehringer Ingelheim, BMS, Daiichi Sankyo, Johnson & Johnson, and Sanofi.

Overview of the anticoagulants market in the US

Technavio’s market research analyst predicts the anticoagulants market in the US to grow at a CAGR of more than 6% by 2020. Increase in the prevalence of deep vein thrombosis (DVT) and thrombosis along with the increased inclination shown toward surgeries which require anticoagulants administration is driving the growth of this market. Moreover, the rising number of the aged population has been adding to this market’s growth as they experience higher risks of developing cardiovascular and renal diseases, leading to thromboembolic and hemorrhagic conditions. With surging incidences of venous thromboembolism and valvular heart diseases among people over 60 years, the sales of anticoagulants in the US will accelerate over the next four years.

Several studies and investigations are being conducted to exploit the use of heparin as an anti-inflammatory and antitumor agent. Researchers are coming up with frequent innovations which have led to an increase in the development of heparin drugs as novel formulations and for the treatment of new indications. For instance, Ockham Biotech is developing inhaled heparin for the treatment of airway diseases, cystic fibrosis, and asthma either alone or in combination with other drugs under various stages of development.

Segmentation by route of administration (ROA) and analysis of the anticoagulants market in the US

  • Oral
  • Injectables

Oral anticoagulants occupied the largest segment of the market in 2015, in terms of ROA and accounted for more than 59% of the total market share. These drugs are used for several coagulation disorders, and primarily in the treatment of AF and DVT/PE. Factors such as approval of novel oral anticoagulants (NOACs), especially the class of factor Xa inhibitors and direct thrombin inhibitors, will augment the use of oral anticoagulants in the US.

Segmentation by drug class and analysis of the anticoagulants market in the US

  • Heparin
  • Factor Xa inhibitors
  • Direct thrombin inhibitors
  • Vitamin K antagonists

During 2015, the Factor Xa inhibitors accounted for the largest share of the market by holding around 42% of the total market. This segment comprises direct factor Xa inhibitors, which occupy 95% share of the market as all the NOACs are included in this class. The approval of NOACs such as rivaroxaban (Xarelto), edoxaban (Savaysa), and apixaban (Eliquis) will lead to the speedy growth of this segment in the coming years.

Competitive landscape and key vendors

The market is highly competitive with the presence of numerous small and large vendors. At present, the market is growing at a high pace because of the increased uptake of NOACs. Vendors are making investments in developing generic formulations for blood coagulation and other novel therapeutic areas. Recently, Daiichi Sankyo witnessed the approval of its oral anticoagulant, which has increased its market share considerably.

Key market vendors include -

  • Boehringer Ingelheim
  • BMS
  • Daiichi Sankyo
  • Johnson & Johnson
  • Sanofi

Other prominent vendors in the anticoagulants market in the US are Armetheon, Aspen, AstraZeneca, Bayer, Cellceutix, Cosmo Pharmaceuticals, CSL Behring, Eisai, GSK, Marathon Pharmaceuticals, Ockham Biotech, Perosphere, Portola Pharmaceuticals, Sagent Pharmaceuticals, The Medicines Company, Urigen Pharmaceuticals, and Valeant Pharmaceuticals.

Key questions answered in the report include

  • What will the market size and the growth rate be in 2020?
  • What are the key factors driving the anticoagulants market in the US?
  • What are the key market trends impacting the growth of the anticoagulants market in the US?
  • What are the challenges to market growth?
  • Who are the key vendors in the anticoagulants market in the US?
  • What are the market opportunities and threats faced by the vendors in the anticoagulants market in the US?
  • Trending factors influencing the market shares of the US region.
  • What are the key outcomes of the five forces analysis of the anticoagulants market in the US?

Technavio also offers customization on reports based on specific client requirement.

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Anticoagulants, also known as blood thinning agents, are drugs that prevent the formation of clots and helps in the free flow of blood in the body. Though they are referred to as blood thinning agents, they do not make the blood thinner, but instead interrupts the overall process of blood coagulation. In the US, vendors like BMS/Pfizer, Janssen Pharmaceutical, Janssen Pharmaceutical, Sanofi, and Aspen will be the primary players for anticoagulants.

The report, anticoagulants market in the US, is part of Technavio’s healthcare and life sciences research portfolio. This portfolio provides a comprehensive market analysis along with the market share, market sizing, and market segmentations covering areas such as cardiovascular and metabolic disorders, central nervous system, oncology, medical imaging, life science research tools, and vaccines. These market research reports provide a perspective on the various market opportunities and market threats along with the key trends that would influence the market growth during the forecast period. It presents insights into the changing competitive landscape and a detailed profiling and market analysis of the vendors. Also covered in the research are the key regions or countries that would have an impact on the market during the assessment years.

Table of Contents

PART 01: Executive summary

  • Highlights

PART 02: Scope of  the report

  • Market overview
  • Top-vendor offerings

PART 03: Market research methodology

  • Research methodology
  • Economic indicators

PART 04: Introduction

  • Key market highlights

PART 05: Anticoagulants: An overview

  • Coagulation of blood
  • Mechanism of action (MOA) of anticoagulants

PART 06: Reimbursement scenario

  • US healthcare reform
  • Reimbursement for prothrombin time/international normalized ratio (PT/INR) tests

PART 07: Anticoagulant reversal agents

PART 08: Approved anticoagulants in US

PART 09: Anticoagulants pipeline portfolio

  • Rivaroxaban
  • Tecarfarin
  • Betrixaban (LY517717)
  • ISIS-FXI antisense
  • LMW Heparin MMX
  • URG101
  • Heparin
  • FXI antibody
  • FXI inhibitor
  • Heparin plus DNAse
  • Heparin plus other inhaled drug

PART 10: Market landscape

  • Global anticoagulants market
  • Anticoagulants market in US
  • Five forces analysis

PART 11: Market segmentation by ROA

  • Oral anticoagulants
  • Injectable anticoagulants

PART 12: Market segmentation by drug class

  • Factor Xa inhibitors
  • Direct thrombin inhibitors
  • Heparin
  • Vitamin K antagonists

PART 13: Market segmentation by application

  • DVT
  • PE
  • Acute coronary syndrome
  • AF
  • Hemodialysis
  • Coronary angioplasty
  • Surgeries

PART 14: Market drivers

  • Growing prevalence of coagulation disorders
  • Increase in number of surgical procedures
  • Increased acceptance of NOACs

PART 15: Impact of drivers

PART 16: Market challenges

  • Extensive use of generic products
  • Side-effects associated with drugs
  • High cost of NOACs
  • Unmet needs for anticoagulant reversal agents

PART 17: Impact of drivers and challenges

PART 18: Market trends

  • Expected exploitation of new therapeutic use
  • Patient assistance programs
  • Declining shares of heparin market

PART 19: Vendor landscape

  • Competitive scenario
  • Market analysis 2015
  • Key vendors of anticoagulants market in US
  • Johnson & Johnson
  • Bristol-Myers Squibb
  • Boehringer Ingelheim
  • Sanofi
  • Upcoming vendors in anticoagulants market in US
  • Daiichi Sankyo
  • Other prominent vendors

PART 20: Appendix

  • List of abbreviations

PART 21: Explore Technavio

Research Framework

Technavio presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers. The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary.


Primary sources

  • Manufacturers and suppliers
  • Channel partners
  • Industry experts
  • Strategic decision makers

Secondary sources

  • Industry journals and periodicals
  • Government data
  • Financial reports of key industry players
  • Historical data
  • Press releases


Data Synthesis

  • Collation of data
  • Estimation of key figures
  • Analysis of derived insights

Data Validation

  • Triangulation with data models
  • Reference against proprietary databases
  • Corroboration with industry experts



  • Market drivers
  • Market challenges
  • Market trends
  • Five forces analysis


  • Market size and forecast
  • Market segmentation
  • Geographical insights
  • Competitive landscape
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