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The 3D cell culture market size is forecast to increase by USD 1.28 billion, accelerating at a CAGR of 15.69% between 2021 and 2026. Market size, historical data (2017-2021), and future projections are presented in terms of value (in USD billion) for all the mentioned segments.
The rising global population contributes to the increasing prevalence of infectious diseases, including global pandemics like Ebola, SARS, swine flu, Zika, and Lassa fever. These challenges underscore the importance of biotechnology and pharmaceutical research in addressing public health concerns. In the 3D cell culture market, obtaining necessary consumables and equipment such as CO2 incubators, bioreactors, and cryostorage systems is essential. However, the growth of the market is evident, particularly in the production of monoclonal antibodies, which find applications across various sectors including medicine, biology, and diagnostic imaging. This trend signifies the continuous innovation and development in the pharmaceutical industry and related fields.
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The market refers to a growing sector in the field of biomedical research and drug discovery. It involves the cultivation of cells in an environment that mimics their natural three-dimensional structure, unlike traditional two-dimensional cultures. It is a cornerstone of biotechnology and pharmaceutical research that experiences continuous growth and innovation. Essential for drug screening and regenerative medicine, cell culture utilizes scaffold and tissue engineering techniques to cultivate cells and develop intricate organoids. Recent strides in microfluidics, biomaterials, and organ-on-a-chip technology have revolutionized the field, enabling precise analysis and drug screening on a microscopic scale. As a vital tool in healthcare and laboratory settings, cell culture remains pivotal in advancing research and development efforts, driving progress in biomedical analysis and industry growth.
The prevalence of infectious diseases is rapidly increasing globally, driven by the expanding population. Outbreaks of viral infections such as Ebola, severe acute respiratory syndrome (SARS), swine flu, Zika, and Lassa fever have emerged as significant global pandemics, spreading within a week. COVID-19, in particular, has had a profound impact worldwide, affecting millions in 2020. Combatting pandemics and epidemics necessitates the development of vaccines and drugs. In recent years, advancements in biotechnology have propelled the R&D of antiviral drugs, cell-based therapies, and vaccines using culture methods. Unlike the traditional egg-based manufacturing process for flu vaccines, which was prevalent for decades, 3D cell culture techniques utilize animal cell lines, offering advantages such as rapid vaccine production and independence from egg supply constraints. This shift in revolutionizing infectious disease treatment and prevention marks a significant milestone in pharmaceutical & biotechnology company's research and developments.
Monoclonal antibodies, and identical immune cells, are experiencing exponential growth within the pharmaceutical industry, finding applications across various domains including biology, diagnostic imaging, medicine, and biochemistry. Their versatility extends to medical realms such as cancer treatments, multiple sclerosis, rheumatoid arthritis, cardiovascular diseases, Crohn's disease, psoriasis, and ulcerative colitis. The rising demand for monoclonal antibodies is propelling the development of innovative production technologies. Large-scale manufacturing facilities are integrating multiple 3D cell culture bioreactors to meet this demand. Notably, industry leaders like Thermo Fisher Scientific employ advanced techniques encompassing stable cell lines, 3D cell culture expansion, purification, and testing. These advancements, coupled with rapid contaminant detection capabilities, are poised to further boost the global 3D cell culture market.
The market demands both consumables and equipment, with equipment costs significantly outweighing consumable expenses. Essential equipment like CO2 incubators, bioreactors, cryostorage systems, and biosafety cabinets incur substantial investment. For instance, a CO2 incubator ranges from USD6,000 to USD14,000, while cryostorage systems exceed USD25,000, and biosafety cabinets surpass USD9,000. Moreover, equipment such as CO2 incubators necessitates frequent cleaning to prevent contamination, ensuring optimal performance. Maintenance of these precision instruments demands meticulous attention and resources, contributing to elevated ownership costs. Consequently, the substantial upfront and maintenance expenses pose barriers to market growth, impeding adoption rates.
In 2021, the cancer and stem cell research segment led the global market and is expected to maintain the highest growth rate. This is driven by the rising cancer prevalence and significant research funding. Innovative 3D culturing techniques are revolutionizing cancer discovery and treatment, with companies like Thermo Fisher Scientific Inc. and Merck KGaA offering products like the 3D Collagen Culture Kit MSDS and AlgiMatrix 3D Culture System to support in cancer and stem cell research.
North America is estimated to contribute 41% to the growth of the global market during the forecast period. Market growth in this region will be faster than the growth of the market in Europe and Rest of World (ROW).
The significant increase in investment in new manufacturing facilities by major companies such as Becton, Dickinson, and Company, Corning Incorporated, and Thermo Fisher Scientific Inc. will facilitate the market growth in North America over the forecast period. This market research report entails detailed information on the competitive intelligence, marketing gaps, and regional opportunities in store for vendors, which will assist in creating efficient business plans.
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The 3D Cell Culture Market is fragmented in nature. Some significant players include 3D Biotek LLC, BICO Group AB, CN Bio Innovations Ltd., Corning Inc., Elveflow, Emulate Inc.
The 3D cell culture market report also includes detailed analyses of the competitive landscape of the market and information about 15 market companies, including:
Greiner Bio-One International GmbH, Hamilton Bonaduz AG, InSphero AG, Lonza Group Ltd., Merck KGaA, PromoCell GmbH, QGel SA , REPROCELL Inc., Synthecon Inc., SynVivo Inc., Tecan Group Ltd., Thermo Fisher Scientific Inc., TissUse GmbH, and MIMETAS BV
The revolutionizing the field of tissue engineering and regenerative medicine. By simulating the complex three-dimensional environment of living tissues, 3D cell culture techniques enable more accurate representations of cell behavior and interactions compared to traditional 2D cultures. This advancement has profound implications across various domains, from drug discovery and cancer research to organ transplantation and regenerative therapies. Moreover, the emergence of innovative technologies like bioreactors, microfluidic devices, and organ-on-chip models platforms further enhances the adoption and consistency in offering researchers unprecedented insights into cellular responses, drug screening, and disease modeling. As investments in this area continue to grow, the growth opportunities in healthcare and laboratory settings are substantial.
The Market encompasses various stakeholders, addressing buying behavior and chronic diseases while advancing personalized medicine. It offers alternatives to animal testing, focusing on pharma and scientific research with considerations for ethical and scientific limitations. Key components include drug testing, human tissues, and organs, albeit facing challenges such as high costs and lack of consistency and standardization. Techniques like microfluidic-based cultures and scaffold-based 3D cell cultures enhance quality control issues over microenvironments. However, issues persist with variability and scalability, requiring regulatory attention. Market players include pharmaceutical and biotechnology companies targeting personalized medicines.
Market Scope |
|
Report Coverage |
Details |
Page number |
120 |
Base year |
2021 |
Forecast period |
2022-2026 |
Growth momentum & CAGR |
Accelerate at a CAGR of 15.69% |
Market growth 2022-2026 |
USD 1.28 billion |
Market structure |
Fragmented |
YoY growth 2021-2022(%) |
15.08 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 41% |
Key countries |
US, Canada, Germany, UK, and China |
Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Key companies profiled |
3D Biotek LLC, BICO Group AB, CN Bio Innovations Ltd., Corning Inc., Elveflow, Emulate Inc., Greiner Bio-One International GmbH, Hamilton Bonaduz AG, InSphero AG, Lonza Group Ltd., Merck KGaA, PromoCell GmbH, QGel SA , REPROCELL Inc., Synthecon Inc., SynVivo Inc., Tecan Group Ltd., Thermo Fisher Scientific Inc., TissUse GmbH, and MIMETAS BV |
Market dynamics |
Parent market analysis, Market forecasting, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period |
Customization purview |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Five Forces Analysis
5 Market Segmentation by Application
6 Customer Landscape
7 Geographic Landscape
8 Drivers, Challenges, and Trends
9 Vendor Landscape
10 Vendor Analysis
11 Appendix
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