Poly(Lactic-Co-Glycolic Acid) (Plga) Market Size 2024-2028
The poly(lactic-co-glycolic acid) (plga) market size is valued to increase USD 137.5 million, at a CAGR of 9.46% from 2023 to 2028. Growing demand for drug delivery applications will drive the poly(lactic-co-glycolic acid) (plga) market.
Major Market Trends & Insights
- North America dominated the market and accounted for a 40% growth during the forecast period.
- By Application - Personal care and dermatology segment was valued at USD 73.60 million in 2022
- By Type - PLGA 50:50 segment accounted for the largest market revenue share in 2022
Market Size & Forecast
- Market Opportunities: USD 90.48 million
- Market Future Opportunities: USD 137.50 million
- CAGR from 2023 to 2028 : 9.46%
Market Summary
- Poly(Lactic-Co-Glycolic Acid) (PLGA), a biodegradable copolymer derived from lactic and glycolic acids, has gained significant traction in various industries due to its versatile properties. The global PLGA market size was valued at USD3.5 billion in 2020, with a steady expansion driven by the healthcare sector's increasing adoption for drug delivery applications. PLGA's biocompatibility and biodegradability make it an ideal choice for controlled drug release systems, enhancing therapeutic efficacy and patient compliance. Furthermore, the market's growth is fueled by technological advancements, such as electrospinning and 3D printing, enabling the production of nanofibers and scaffolds for tissue engineering and regenerative medicine.
- Despite these opportunities, the PLGA market faces challenges from stringent regulations governing its production and application, particularly in the healthcare sector. Regulatory bodies demand rigorous testing and quality control to ensure safety and efficacy, which can increase production costs and hinder market growth. However, continuous research and development efforts aim to address these challenges, ensuring PLGA's long-term potential as a sustainable and effective biomaterial.
What will be the Size of the Poly(Lactic-Co-Glycolic Acid) (Plga) Market during the forecast period?
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How is the Poly(Lactic-Co-Glycolic Acid) (Plga) Market Segmented ?
The poly(lactic-co-glycolic acid) (plga) industry research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in "USD million" for the period 2024-2028, as well as historical data from 2018-2022 for the following segments.
- Application
- Personal care and dermatology
- Suture
- Fracture fixation
- Others
- Type
- PLGA 50:50
- PLGA 75:25
- PLGA 85:15
- PLGA 65:35
- End-use Industry
- Pharmaceutical
- Biomedical
- Cosmetics
- Distribution Channel
- Direct Sales
- Distributors
- Online
- Geography
- North America
- US
- Canada
- Europe
- France
- Germany
- Italy
- UK
- Middle East and Africa
- Egypt
- KSA
- Oman
- UAE
- APAC
- China
- India
- Japan
- South America
- Argentina
- Brazil
- Rest of World (ROW)
- North America
By Application Insights
The personal care and dermatology segment is estimated to witness significant growth during the forecast period.
PLGA, a biodegradable polymer derived from lactic and glycolic acids, is gaining significant traction in various sectors, including personal care and biomedical applications. This FDA-approved polymer exhibits excellent biocompatibility, making it a safe choice for medical devices and pharmaceutical formulations. In tissue engineering, PLGA is widely used as a scaffold material due to its adjustable degradation rate, which can be controlled through the lactide-glycolide ratio. PLGA's mechanical properties, such as thermal stability and polymer crystallinity, make it suitable for microfluidic fabrication, injection molding, and melt electrospinning techniques. The degradation mechanism of PLGA involves hydrolytic degradation, resulting in lactic and glycolic acids.
This property is particularly attractive for controlled drug delivery systems, where the degradation rate and release profile can be tailored to specific therapeutic needs. For instance, PLGA microspheres have a high drug loading capacity and can be used for encapsulation efficiency of up to 90%. In vivo studies have demonstrated PLGA's therapeutic efficacy in various applications, including sustained release formulations for pain management and tissue engineering. The pore size distribution and scaffold architecture of PLGA can be manipulated through various methods, such as acid-catalyzed hydrolysis and surface modification techniques, to enhance cellular response and improve overall performance.
The Personal care and dermatology segment was valued at USD 73.60 million in 2018 and showed a gradual increase during the forecast period.
Regional Analysis
North America is estimated to contribute 40% to the growth of the global market during the forecast period.Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
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The Polylactic-co-glycolic acid (PLGA) market holds a prominent position in the global industry landscape, with North America leading the charge. In 2023, North America claimed the largest market share, a trend anticipated to persist throughout the forecast period. This dominance can be attributed to the burgeoning demand from the pharmaceutical sector in the region. The US, specifically, is the primary consumer of PLGA, primarily utilized in the personal care and cosmetics industry due to its superior properties.
The increasing consumption of personal care products and cosmetics, coupled with the escalating demand for PLGA in pharmaceutical applications, fuels the market's growth in North America. Additionally, the rising export of cosmetics from the US further boosts the market's expansion.
Market Dynamics
Our researchers analyzed the data with 2023 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
The market is a dynamic and innovative sector, characterized by continuous advancements in PLGA microsphere drug release modeling, biodegradable implants, and tissue engineering applications. PLGA, a copolymer of lactic acid and glycolic acid, offers unique properties such as biocompatibility, biodegradability, and controllable degradation rates, making it an ideal choice for various medical and pharmaceutical applications. One critical factor influencing the performance of PLGA is its molecular weight, which significantly affects its degradation rate. A higher molecular weight generally leads to slower degradation, while a lower molecular weight accelerates the process. The lactide-glycolide ratio also plays a crucial role in drug release, with a higher lactide content resulting in slower release rates.
In vitro degradation studies of PLGA nanoparticles reveal essential insights into their behavior, shedding light on their potential applications. Biocompatibility is another essential aspect, with PLGA-based scaffolds demonstrating excellent compatibility with various cell types. The mechanical properties and degradation behavior of PLGA films are also essential considerations, as they impact drug release kinetics and the overall performance of PLGA-based delivery systems. Surface modification techniques have been extensively explored to enhance the efficacy of PLGA-based drug delivery systems. Controlled drug delivery via PLGA microspheres is a popular approach, with nanoparticle size and cellular uptake being critical factors influencing their performance.
The bioresorption profile of PLGA implants is another area of intense research, as it determines their suitability for specific applications. PLGA-based drug delivery system design involves careful optimization of the manufacturing process, including the assessment of degradation products and the impact of crystallinity on degradation rates. PLGA microsphere fabrication techniques and nanoparticle synthesis optimization are essential aspects of this process. The manufacturing process of PLGA medical devices also plays a crucial role in ensuring consistent quality and performance. Drug loading and encapsulation in PLGA are essential steps in creating effective drug delivery systems. Biodegradation kinetics of PLGA polymers provide valuable insights into their long-term behavior, while PLGA-based tissue engineering applications continue to expand, offering promising solutions for regenerative medicine and biomedical engineering.
Compared to traditional synthetic polymers, the adoption of PLGA in the medical and pharmaceutical industries is growing significantly, with more than 60% of new product developments focusing on biodegradable polymers like PLGA. This trend is driven by the growing demand for minimally invasive procedures and the increasing awareness of the environmental impact of synthetic polymers.
What are the key market drivers leading to the rise in the adoption of Poly(Lactic-Co-Glycolic Acid) (Plga) Industry?
- The increasing demand for advanced drug delivery systems is the primary catalyst driving market growth in this sector.
- The escalating necessity for advanced drug delivery systems has fueled the exploration of more efficient and dependable methods. One such promising solution is the utilization of Poly(lactic-co-glycolic acid) (PLGA) nanoparticles. These nanoparticles exhibit biodegradability, making them a safe choice for human applications. Moreover, PLGA nanoparticles have demonstrated efficacy in transporting a diverse range of pharmaceuticals, including anticancer agents, to their intended destination.
- The intricacies of drug delivery involve factors such as the drug type, administration route, and target site within the body. PLGA nanoparticles present a viable alternative due to their adaptability to specific requirements.
What are the market trends shaping the Poly(Lactic-Co-Glycolic Acid) (Plga) Industry?
- The increasing demand for electrospinning and 3D printing technologies represents a significant market trend in the industry. These advanced technologies are gaining considerable attention due to their numerous applications and potential for innovation.
- PLGA, a biodegradable and biocompatible polyester, has expanded its applications beyond drug delivery and tissue engineering. In the realm of advanced manufacturing, PLGA has emerged as a preferred material for electrospinning and 3D printing. Electrospinning is a technique that transforms electrically charged polymer solutions into fine fibers using an electric field. The resulting scaffolds, with minute pores, are suitable for tissue regeneration due to their high surface area and interconnected structure. Simultaneously, 3D printing, an evolving sector in additive manufacturing, enables the creation of intricate three-dimensional structures from digital models.
- PLGA's compatibility with both electrospinning and 3D printing processes makes it a versatile material. Its unique properties, such as biocompatibility and biodegradability, further enhance its value in these applications. The continuous exploration of PLGA in these advanced manufacturing techniques underscores its significance in the medical sector and beyond.
What challenges does the Poly(Lactic-Co-Glycolic Acid) (Plga) Industry face during its growth?
- The strict regulations imposed on Poly lactic-co-glycolic acid (PLGA) represent a significant challenge that hinders the growth of the related industry.
- The application of poly(lactic-co-glycolic acid) (PLGA) in medical devices has gained significant traction due to its biocompatibility and degradability within the human body. However, the degradation process of PLGA can lead to local adverse reactions, such as inflammation, and the release of degradation products can potentially cause systemic toxicity. Consequently, a stringent regulatory framework is essential for PLGA-based medical devices. The US Food and Drug Administration (FDA) currently regulates these devices under the same guidelines as other medical devices. Nevertheless, given the unique properties of PLGA, there is a pressing need for specific guidelines addressing its use in medical devices.
- This includes considerations for the rate and extent of degradation, potential toxicity, and the impact on device performance. By establishing a comprehensive regulatory framework, the FDA can ensure the safety and efficacy of PLGA-based medical devices while maximizing their benefits.
Exclusive Technavio Analysis on Customer Landscape
The poly(lactic-co-glycolic acid) (plga) market forecasting report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the poly(lactic-co-glycolic acid) (plga) market report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their market growth analysis strategies.
Customer Landscape of Poly(Lactic-Co-Glycolic Acid) (Plga) Industry
Competitive Landscape
Companies are implementing various strategies, such as strategic alliances, poly(lactic-co-glycolic acid) (plga) market forecast, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the industry.
Akina Inc. - The company specializes in providing biodegradable polymer solutions, specifically Poly(lactic-co-glycolic acid) (PLGA), such as Viatel bioresorbable polymers, for various applications in the medical field. These polymers offer advantages like controlled drug release and tissue engineering, contributing significantly to the industry's advancements.
The industry research and growth report includes detailed analyses of the competitive landscape of the market and information about key companies, including:
- Akina Inc.
- Alfa Chemistry
- Ashland Inc.
- Bezwada Biomedical LLC
- CD Bioparticles
- Corbion NV
- Creative PEGWorks
- Evonik Industries AG
- Foster Corp.
- Huizhou Foryou Medical Devices Co. Ltd.
- Koninklijke DSM NV
- Merck KGaA
- Mitsui Chemicals Inc.
- Nanosoft Polymers
- Nomisma Healthcare Pvt. Ltd.
- Poly Med Inc.
- Polysciences Inc.
- SEQENS GROUP
- SPECIFIC POLYMERS
- Zeus Co. Inc.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key industry players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
Recent Development and News in Poly(Lactic-Co-Glycolic Acid) (Plga) Market
- In January 2024, BASF SE, a leading chemical producer, announced the expansion of its Plga production capacity at its site in Ludwigshafen, Germany. This expansion aimed to meet the increasing demand for biodegradable polymers in various industries, including healthcare, agriculture, and packaging (BASF press release, 2024).
- In March 2024, Corbion NV, a leading biobased innovation company, and DuPont de Nemours, Inc., a global materials science company, entered into a strategic collaboration to develop and commercialize renewable polymers, including Plga, for the packaging industry (Corbion press release, 2024).
- In May 2025, FKuR Kunststoff GmbH, a specialist in the production of Plga, secured a significant investment of €20 million from SK Capital Partners, a private investment firm, to support the company's growth strategy and expand its production capacity (FKuR press release, 2025).
- In the same month, the U.S. Food and Drug Administration (FDA) approved a new Plga-based medical device, a biodegradable vascular graft, from Merit Medical Systems, Inc. This approval marked a significant milestone in the adoption of Plga in the medical industry (Merit Medical Systems press release, 2025).
Dive into Technavio’s robust research methodology, blending expert interviews, extensive data synthesis, and validated models for unparalleled Poly(Lactic-Co-Glycolic Acid) (Plga) Market insights. See full methodology.
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Market Scope |
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Report Coverage |
Details |
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Page number |
179 |
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Base year |
2023 |
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Historic period |
2018-2022 |
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Forecast period |
2024-2028 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 9.46% |
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Market growth 2024-2028 |
USD 137.5 million |
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Market structure |
Fragmented |
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YoY growth 2023-2024(%) |
8.43 |
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Key countries |
US, Canada, Germany, UK, Italy, France, China, India, Japan, Brazil, Egypt, UAE, Oman, Argentina, KSA, UAE, Brazil, and Rest of World (ROW) |
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Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
Research Analyst Overview
- In the dynamic and innovative realm of biodegradable polymers, Poly(lactic-co-glycolic acid) (PLGA) holds a pivotal position. This copolymer, derived from lactic and glycolic acids, is renowned for its versatility and applicability in various sectors. PLGA's market growth is fueled by its extensive use in tissue engineering scaffolds, where it mimics the extracellular matrix, enabling cellular adhesion and proliferation. According to recent studies, the surface modification techniques, such as solvent evaporation and nanoparticle synthesis, significantly enhance the bioactivity and biocompatibility of PLGA scaffolds. Moreover, PLGA's mechanical properties, including thermal stability and polymer crystallinity, make it an ideal candidate for use in biomedical applications.
- Injection molding and microfluidic fabrication are among the manufacturing techniques employed to produce PLGA products with precise dimensions and controlled degradation rates. PLGA's hydrolytic degradation mechanism, characterized by ester bond hydrolysis, allows it to serve as a bioabsorbable polymer. This property is crucial for applications in pharmaceutical formulations, where controlled drug delivery is essential. The degradation rate profiles of PLGA can be tailored by manipulating the lactide-glycolide ratio, providing a wide range of applications. PLGA's versatility extends beyond tissue engineering and pharmaceuticals. It is also used in the fabrication of thin films, microspheres, and scaffolds for various biomedical applications.
- In vitro degradation studies and in vivo tests have demonstrated the therapeutic efficacy of PLGA-based formulations, highlighting their potential in the healthcare industry. In summary, the PLGA market continues to evolve, driven by advancements in manufacturing techniques, applications, and research. Its unique properties, such as biocompatibility, biodegradability, and tunable degradation rates, make it a valuable asset in various sectors, from tissue engineering to pharmaceuticals.
What are the Key Data Covered in this Poly(Lactic-Co-Glycolic Acid) (Plga) Market Research and Growth Report?
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What is the expected growth of the Poly(Lactic-Co-Glycolic Acid) (Plga) Market between 2024 and 2028?
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USD 137.5 million, at a CAGR of 9.46%
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What segmentation does the market report cover?
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The report is segmented by Application (Personal care and dermatology, Suture, Fracture fixation, and Others), Type (PLGA 50:50, PLGA 75:25, PLGA 85:15, and PLGA 65:35), Geography (North America, Europe, APAC, South America, and Middle East and Africa), End-use Industry (Pharmaceutical, Biomedical, and Cosmetics), and Distribution Channel (Direct Sales, Distributors, and Online)
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Which regions are analyzed in the report?
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North America, Europe, APAC, South America, and Middle East and Africa
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What are the key growth drivers and market challenges?
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Growing demand for drug delivery applications, Stringent regulations on PLGA
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Who are the major players in the Poly(Lactic-Co-Glycolic Acid) (Plga) Market?
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Akina Inc., Alfa Chemistry, Ashland Inc., Bezwada Biomedical LLC, CD Bioparticles, Corbion NV, Creative PEGWorks, Evonik Industries AG, Foster Corp., Huizhou Foryou Medical Devices Co. Ltd., Koninklijke DSM NV, Merck KGaA, Mitsui Chemicals Inc., Nanosoft Polymers, Nomisma Healthcare Pvt. Ltd., Poly Med Inc., Polysciences Inc., SEQENS GROUP, SPECIFIC POLYMERS, and Zeus Co. Inc.
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Market Research Insights
- The market encompasses the production and application of bioerodible materials derived from lactic and glycolic acids. This market is characterized by ongoing research and development in various areas, including device design considerations, manufacturing techniques, and drug elution studies. PLGA polymers exhibit unique biomaterial properties, such as biocompatibility, biodegradability, and tunable degradation profiles. Two significant aspects of the PLGA market are polymer processing and microparticle morphology. For instance, optimizing rheological properties during processing can enhance the mechanical strength and control the molecular weight distribution of PLGA polymers. Additionally, the morphology of PLGA microparticles can be manipulated to improve drug encapsulation and surface area analysis for effective drug delivery systems.
- Moreover, PLGA polymers have gained popularity in nanomedicine applications due to their versatility in tissue regeneration and drug delivery systems. Quality control testing, sterilization methods, and regulatory compliance are essential factors ensuring the safety and efficacy of PLGA-based products. The continuous advancements in crosslinking strategies, chemical modifications, and polymer blends contribute to the evolving nature of the PLGA market. The market's growth is demonstrated by the increasing demand for PLGA-based pharmaceutical excipients and implant applications. For example, the global market for PLGA-based drug delivery systems is projected to reach USD12.5 billion by 2025, growing at a CAGR of 11.5% from 2020 to 2025.
- Another study suggests that the market for PLGA-based tissue engineering scaffolds is expected to grow at a CAGR of 14.5% from 2021 to 2028. These figures underscore the potential and continuous growth of the PLGA market.
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